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[1]黃明翥,周紅海,何心愉,等.《醫(yī)宗金鑒·正骨心法要旨》中治療傷科瘀腫疼痛方劑的用藥規(guī)律分析[J].中醫(yī)正骨,2023,35(10):37-41.
　HUANG Mingzhu,ZHOU Honghai,HE Xinyu,et al.A data mining-based analysis of clinical medication rules of traumatologic prescriptions for treatment of blood stasis,swelling and pain in Yizong Jinjian,Essentials of Bone Orthopedics[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2023,35(10):37-41.
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《醫(yī)宗金鑒·正骨心法要旨》中治療傷科瘀腫疼痛方劑的用藥規(guī)律分析()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期數(shù):
2023年10期
頁碼:
37-41
欄目:
文獻(xiàn)研究
出版日期:
2023-10-20

文章信息/Info

Title:
A data mining-based analysis of clinical medication rules of traumatologic prescriptions for treatment of blood stasis,swelling and pain in Yizong Jinjian,Essentials of Bone Orthopedics
作者:
黃明翥; 周紅海; 何心愉; 徐濤; 吳周統(tǒng)
廣西中醫(yī)藥大學(xué)骨傷學(xué)院,廣西 南寧 530001
Author(s):
HUANG Mingzhu; ZHOU Honghai; HE Xinyu; XU Tao; WU Zhoutong
College of Orthopaedics and Traumatology of Guangxi University of Chinese Medicine,Nanning 530001,Guangxi,China
關(guān)鍵詞:
中醫(yī)藥學(xué)文獻(xiàn);  《醫(yī)宗金鑒》;  中醫(yī)骨傷科疾病;  方劑構(gòu)成;  數(shù)據(jù)挖掘;  聚類分析
Keywords:
med pharmacol literature TCM;  Yi Zong Jin Jian;  orthopedic traumatologic diseases(TCM);  constitution of formula;  data mining;  cluster analysis
摘要:
目的:分析《醫(yī)宗金鑒·正骨心法要旨》中治療傷科瘀腫疼痛方劑的用藥規(guī)律。方法:收集《醫(yī)宗金鑒·正骨心法要旨》中治療傷科瘀腫疼痛的方劑,對組方中藥物的出現(xiàn)頻次及藥性、藥味、歸經(jīng)、功效進(jìn)行統(tǒng)計(jì),分析用藥規(guī)律。結(jié)果:共收集到《醫(yī)宗金鑒·正骨心法要旨》中治療瘀腫疼痛的內(nèi)服、外用方劑57首,涉及中藥179味。出現(xiàn)頻次≥5的藥物有35味,當(dāng)歸出現(xiàn)頻次最多。藥性出現(xiàn)頻次較高的為溫、寒、平,藥味出現(xiàn)頻次較高的為辛、苦、甘,歸經(jīng)主要?dú)w肝經(jīng)、脾經(jīng)、心經(jīng),藥物功效主要為補(bǔ)虛、活血、清熱。關(guān)聯(lián)藥物數(shù)最多的藥物是當(dāng)歸,規(guī)則支持度最高的藥物組合為川芎-當(dāng)歸; 增益最高的藥物組合為生姜-人參、甘草。核心藥物組合有4組,分別為人參-生姜-大棗-茯苓-白術(shù)、柴胡-梔子-半夏-黃芩、當(dāng)歸-川芎-熟地黃-白芍、血竭-木香-酒。結(jié)論:《醫(yī)宗金鑒·正骨心法要旨》中治療傷科瘀腫疼痛的方劑多采用性溫、味辛、歸肝經(jīng)的藥物,核心藥物組合以健脾益氣、疏肝清火、補(bǔ)血活血、活血止痛藥物為主,用藥規(guī)律符合其專從血論、氣血并重、消補(bǔ)并用的治傷思想。
Abstract:
Objective:To analyze the clinical medication rules of traumatologic prescriptions for treatment of blood stasis,swelling and pain in Yizong Jinjian,Essentials of Bone Orthopedics.Methods:The traumatologic prescriptions aimed at treating blood stasis,swelling and pain were extracted from Yizong Jinjian,Essentials of Bone Orthopedics,and the occurrence frequency,medicinal property,medicinal flavor,meridian tropism and efficacy of each Chinese herbs(CHs)contained in the extracted prescriptions were statistically analyzed for excavating the clinical medication rules.Results:Fifty-seven oral and external-applied prescriptions for treatment of blood stasis,swelling and pain in Yizong Jinjian,Essentials of Bone Orthopedics were included in the final analysis,involving 179 CHs,among which 35 ones displayed a occurrence frequency of≥5,and the most frequently used CH was Angelica Sinensis.The results of statistics showed that,among the 57 oral and external-applied prescriptions,the CHs were often the ones for reinforcing deficiency,activating blood and clearing heat,which were often warm,cold and neutral in property and pungent,bitter and sweet in flavor and mainly acted on the liver meridians,spleen meridians and heart meridians in turn.The results of association rule analysis revealed that the CH with the highest correlation was Angelica Sinensis; the herb combination with the highest support was Chuanxiong Rhizoma-Angelica Sinensis; and the herb combination with the highest gain was Zingiberis Rhizoma Recens-Ginseng Radix et Rhizoma,Glycyrrhiza Uralensis.The results of cluster analysis on the 35 high occurrence frequency herbs generated 4 core herb combinations,namely Ginseng Radix et Rhizoma-Zingiberis Rhizoma Recens-Jujubae Fructus-Poria Cocos-Atractmlodis Macrocephalae Rhizoma,Bupleuri Radix-Gardeniae Fructus-Pinelliae Rhizoma-Scutellaria Baicalensis,Angelica Sinensis-Chuanxiong Rhizoma-Rehmanniae Radix Praeparata-Paeoniae Radix Alba and Draconis Sanguis-Aucklandiae Radix-Medicinal Wine.Conclusion:The CHs are often the ones presented with warm property and pungent flavor and mainly act on liver meridians in the traumatologic prescriptions aimed at treating blood stasis,swelling and pain in Yizong Jinjian,Essentials of Bone Orthopedics,and the core herb combinations are mainly the ones for strengthening spleen and reinforcing Qi,soothing liver and clearing internal heat,nourishing blood and activating blood as well as activating blood for relieving pain.The medication rules conform to the thoughts of focusing on blood,paying equal attention to Qi and blood,and stressing on the combination of elimination and tonification in treatment of orthopaedic and traumatic diseases.

參考文獻(xiàn)/References:

[1] 秦嵩雯.《醫(yī)宗金鑒·正骨心法要旨》中骨骼名詞的考證[J].中醫(yī)正骨,2021,33(12):46-47.
[2] 左世國,李姣姣,向昱陽.《醫(yī)宗金鑒·正骨心法要旨》中骨傷外治處方的用藥規(guī)律分析[J].中醫(yī)正骨,2022,34(2):40-43.
[3] 吳謙.御纂醫(yī)宗金鑒(下冊)[M].鄭金生,整理.北京:人民衛(wèi)生出版社,2006:1933-1994.
[4] 國家藥典委員會.中華人民共和國藥典(2020年版 一部)[M].北京:中國醫(yī)藥科技出版社,2020.
[5] 鐘贛生,楊柏燦.中藥學(xué)[M].11版.北京:中國中醫(yī)藥出版社,2021:55-439.
[6] 國家中醫(yī)藥管理局《中華本草》編委會.《中華本草》[M].上海:上海科學(xué)技術(shù)出版社,1999.
[7] YANG C,NIU S,YU L,et al.The aqueous extract of Angelica sinensis,a popular Chinese herb,inhibits wear debris-induced inflammatory osteolysis in mice[J].J Surg Res,2012,176(2):476-483.
[8] 吳宏,姜蓉,鄭敏,等.人參多糖和當(dāng)歸多糖誘導(dǎo)人內(nèi)皮細(xì)胞表達(dá)造血生長因子的實(shí)驗(yàn)研究[J].中國中西醫(yī)結(jié)合雜志,2002,22(9):687-690.
[9] 董培良,李慧,韓華.當(dāng)歸及其藥對的研究進(jìn)展[J].中醫(yī)藥信息,2019,36(2):127-130.
[10] 王鳳龍,劉員,張來賓,等.當(dāng)歸抗炎鎮(zhèn)痛作用研究進(jìn)展[J].中國實(shí)驗(yàn)方劑學(xué)雜志,2021,27(15):197-209.
[11] 鄒秀娟,郭玉芹,欒正麗,等.川芎—當(dāng)歸藥對治療類風(fēng)濕關(guān)節(jié)炎作用機(jī)制的網(wǎng)絡(luò)藥理學(xué)分析[J].中醫(yī)臨床研究,2023,15(19):31-36.
[12] 張瑩瑩,張科,宋崟,等.“川芎-當(dāng)歸”藥對主要活性成分的網(wǎng)絡(luò)藥理學(xué)研究[J].安徽醫(yī)藥,2023,27(1):19-24.
[13] 趙達(dá)安,劉肖.張仲景用姜方法探析[J].甘肅中醫(yī),2009,22(1):65.
[14] 許小雪,郭盛,尚爾鑫,等.基于R語言數(shù)據(jù)挖掘的姜-棗藥對配伍特點(diǎn)及組方規(guī)律分析[J].中草藥,2023,54(11):3594-3607.
[15] 蔡可珍,鄭琴,魏韶鋒,等.四君子湯的研究進(jìn)展及質(zhì)量標(biāo)志物的預(yù)測[J/OL].中華中醫(yī)藥學(xué)刊:1-13[2023-04-01].http://kns.cnki.net/kcms/detail/21.1546.R.20230602.1444.002.html.
[16] 劉甜甜,姚魁武,段錦龍,等.經(jīng)方小柴胡湯論治冠心病證驗(yàn)[J].時(shí)珍國醫(yī)國藥,2019,30(9):2216-2218.
[17] 徐玉婷,李若照,陳剛.小柴胡湯加減對腦卒中后眩暈血液流變學(xué)指標(biāo)的影響[J].中華中醫(yī)藥學(xué)刊,2020,38(1):233-236.
[18] 戴縉,楊天仁.試述藥物歸經(jīng)、引經(jīng)藥、藥引、方劑歸經(jīng)的起源與關(guān)系[J].中醫(yī)藥學(xué)報(bào),2018,46(1):101-103.
[19] 蘭昀羲,胡宇,黃巍,等.引經(jīng)藥研究現(xiàn)狀及展望[J].中華中醫(yī)藥雜志,2022,37(9):5270-5272.
[20] 李華鵬,桑立紅,侯準(zhǔn),等.中藥酒制的研究概況[J].中藥材,2011,34(3):478-481.
[21] 劉慧敏,劉雪梅,江雨柔,等.酒在中藥制藥與用藥過程中的古今研究進(jìn)展[J].中草藥,2022,53(11):3538-3549.

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備注/Memo

備注/Memo:
基金項(xiàng)目:廣西壯族自治區(qū)中醫(yī)藥局科研課題(GXZYA20220117,20210068)
通訊作者:周紅海 E-mail:[email protected]
更新日期/Last Update: 1900-01-01