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[1]王嘯華,謝林.椎間盤退變的生物療法研究進(jìn)展[J].中醫(yī)正骨,2023,35(07):40-45.
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椎間盤退變的生物療法研究進(jìn)展()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期數(shù):
2023年07期
頁碼:
40-45
欄目:
綜述
出版日期:
2023-07-20

文章信息/Info

作者:
王嘯華謝林
(南京中醫(yī)藥大學(xué)附屬中西醫(yī)結(jié)合醫(yī)院,江蘇 南京 210028)
關(guān)鍵詞:
椎間盤退化 生物療法 綜述
摘要:
椎間盤退變(intervertebral disc degeneration,IDD)是造成脊柱不穩(wěn)的主要因素之一,盡管目前學(xué)術(shù)界尚未就IDD的具體機(jī)制達(dá)成共識(shí),但研究者一直在從多個(gè)角度尋求相關(guān)的治療方法。生物療法被認(rèn)為可以恢復(fù)退變椎間盤的生物力學(xué)特性,并促進(jìn)其內(nèi)源性再生,是目前研究的熱點(diǎn)。本文概述了IDD的基本機(jī)制,并對(duì)小分子療法、干細(xì)胞療法、基因療法及組織工程療法等IDD生物療法的研究進(jìn)展進(jìn)行了綜述,以期為IDD的臨床治療提供新的思路。

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備注/Memo

備注/Memo:
基金項(xiàng)目:江蘇省中醫(yī)藥科技發(fā)展計(jì)劃項(xiàng)目(ZD202008) 通訊作者:謝林 E-mail:[email protected]
更新日期/Last Update: 1900-01-01