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[1]劉銳,龔德飛,班正濤,等.經(jīng)皮椎體成形術(shù)治療骨質(zhì)疏松性椎體壓縮骨折術(shù)中骨水泥滲漏的危險(xiǎn)因素分析[J].中醫(yī)正骨,2022,34(11):14-17，26.
　LIU Rui,GONG Defei,BAN Zhengtao,et al.Risk factors for bone cement leakage during percutaneous vertebroplasty treatment of osteoporotic vertebral compression fractures[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2022,34(11):14-17，26.
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經(jīng)皮椎體成形術(shù)治療骨質(zhì)疏松性椎體壓縮骨折術(shù)中骨水泥滲漏的危險(xiǎn)因素分析()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第34卷
期數(shù):
2022年11期
頁碼:
14-17，26
欄目:
臨床研究
出版日期:
2022-11-11

文章信息/Info

Title:
Risk factors for bone cement leakage during percutaneous vertebroplasty treatment of osteoporotic vertebral compression fractures
作者:
劉銳1; 龔德飛1; 班正濤1; 劉汝專1; 黃民鋒1; 魏紀(jì)湖2; 李沛楨2; 周華亮2
(1.廣西中醫(yī)藥大學(xué)附屬瑞康醫(yī)院,廣西 南寧 530011; 2.廣西中醫(yī)藥大學(xué)研究生院,廣西 南寧 530001)
Author(s):
LIU Rui1; GONG Defei1; BAN Zhengtao1; LIU Ruzhuan1; HUANG Minfeng1; WEI Jihu2; LI Peizhen2; ZHOU Hualiang2
1.Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine,Nanning 530011,Guangxi,China 2.Graduate School of Guangxi University of Traditional Chinese Medicine,Nanning 530001,Guangxi,China
關(guān)鍵詞:
骨質(zhì)疏松性骨折;  脊柱骨折;  骨折; 壓縮性;  椎體成形術(shù);  手術(shù)中并發(fā)癥;  骨粘合劑;  危險(xiǎn)因素;  Logistic模型
Keywords:
osteoporotic fractures;  spinal fractures;  fractures; compression;  vertebroplasty;  intraoperative complications;  bone cements;  risk factors;  logistic models
摘要:
目的:分析經(jīng)皮椎體成形術(shù)(percutaneous vertebroplasty,PVP)治療骨質(zhì)疏松性椎體壓縮骨折(osteoporotic vertebral compression fracture,OVCF)術(shù)中骨水泥滲漏的危險(xiǎn)因素。方法:選擇2017年6月至2021年6月采用PVP治療的307例OVCF患者,從病歷系統(tǒng)中收集患者的年齡、性別、病程、外傷史、基礎(chǔ)疾病(高血壓、糖尿病)、骨折節(jié)段、椎體骨折類型、椎體壓縮程度、椎體后緣骨質(zhì)是否突入椎管、椎體裂隙征、單側(cè)或雙側(cè)穿刺、一次治療椎體數(shù)量、單個椎體骨水泥注射量、骨水泥彌散類型、手術(shù)時間、骨水泥是否滲漏等信息。先進(jìn)行單因素Logistic回歸分析,再將單因素分析結(jié)果中P<0.150的變量作為自變量進(jìn)行多因素Logistic回歸分析。結(jié)果:307例OVCF患者共涉及371椎,其中195椎發(fā)生骨水泥滲漏、176椎未發(fā)生骨水泥滲漏。單因素Logistic回歸分析結(jié)果顯示,年齡(P=0.118)、基礎(chǔ)疾病(高血壓、糖尿病)(P=0.109)、骨水泥彌散類型(P=0.003)、手術(shù)時間(P=0.005)、椎體壓縮程度(P=0.012)可作為多因素分析的自變量。多因素Logistic回歸分析結(jié)果顯示,骨水泥彌散類型為彌散型、手術(shù)時間<40 min是PVP治療OVCF術(shù)中骨水泥滲漏的獨(dú)立危險(xiǎn)因素[B=0.636,P=0.009,OR=1.899,95%CI(1.171,3.047); B=0.574,P=0.015,OR=1.776,95%CI(1.118,2.820)]。結(jié)論:手術(shù)時間<40 min、骨水泥呈彌散型分布是PVP治療OVCF術(shù)中骨水泥滲漏的獨(dú)立危險(xiǎn)因素。
Abstract:
Objective:To investigate the risk factors for bone cement leakage during percutaneous vertebroplasty(PVP)for treatment of osteoporotic vertebral compression fractures(OVCF).Methods:Three hundred and seven OVCF patients treated with PVP from June 2017 to June 2021 were included retrospectively.Through the medical records systems,the information of age,gender,disease course,trauma history,underlying disease(hypertension and diabetes),fracture segment,vertebral fracture type,vertebral compression degree,osteophyte protruding into vertebral canal,intravertebral cleft,puncture method(unilateral or bilateral),number of vertebral body treated at one time,amount of bone cement for single vertebral body,cement distribution type,duration of surgery,and cement leakage were collected.Univariate logistic regression analysis was performed first,and variables with a P value of<0.150 were further regarded as independent variables for multivariate logistic regression analysis.Results:The 307 OVCF cases involved 371 vertebral bodies,in which 195 vertebral bodies presented cement leakage and 176 did not.The results of univariate logistic regression showed that age(P=0.118),underlying disease(hypertension and diabetes)(P=0.109),bone cement distribution type(P=0.003),duration of surgery(P=0.005),and vertebral compression degree(P=0.012)met the requirements of being the independent variables for multivariate logistic regression analysis.The results of multivariate logistic regression analysis showed that diffuse distribution of bone cement and shortened duration of surgery(less than 40 min)were independent risk factors for bone cement leakage during PVP treatment of OVCF(B=0.636,P=0.009,OR=1.899,95%CI(1.171,3.047); B=0.574,P=0.015,OR=1.776,95%CI(1.118,2.820)).Conclusion:Shortened duration of surgery(less than 40 min)and diffuse distribution of bone cement are independent risk factors for bone cement leakage during PVP treatment of OVCF.

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備注/Memo

備注/Memo:
基金項(xiàng)目:廣西壯族自治區(qū)中醫(yī)藥管理局自籌經(jīng)費(fèi)科研課題(GXZYZ20210157) 通訊作者:龔德飛 E-mail:[email protected]
更新日期/Last Update: 1900-01-01