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[1]楊煥瑩,王想福,趙道洲,等.口服獨活寄生湯治療經(jīng)皮內(nèi)窺鏡下腰椎間盤切除術(shù)后殘余癥狀的Meta分析[J].中醫(yī)正骨,2022,34(07):34-39.
　YANG Huanying,WANG Xiangfu,ZHAO Daozhou,et al.Oral application of Duhuo Jisheng Tang(獨活寄生湯)for treatment of residual symptoms following percutaneous endoscopic lumbar discectomy:a meta-analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2022,34(07):34-39.
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口服獨活寄生湯治療經(jīng)皮內(nèi)窺鏡下腰椎間盤切除術(shù)后殘余癥狀的Meta分析()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第34卷
期數(shù):
2022年07期
頁碼:
34-39
欄目:
文獻(xiàn)研究
出版日期:
2022-07-20

文章信息/Info

Title:
Oral application of Duhuo Jisheng Tang(獨活寄生湯)for treatment of residual symptoms following percutaneous endoscopic lumbar discectomy:a meta-analysis
作者:
楊煥瑩1; 王想福2; 趙道洲2; 李晨旭2; 張萬乾1; 陳偉國2; 桑廷瑞1; 張超1; 丁艷芳1; 張晶博1
(1.甘肅中醫(yī)藥大學(xué),甘肅 蘭州 730000; 2.甘肅省中醫(yī)院,甘肅 蘭州 730050)
Author(s):
YANG Huanying1; WANG Xiangfu2; ZHAO Daozhou2; LI Chenxu2; ZHANG Wanqian1; CHEN Weiguo2; SANG Tingrui1; ZHANG Chao1; DING Yanfang1; ZHANG Jingbo1
1.Gansu University of Chinese Medicine,Lanzhou 730000,Gansu,China 2.Gansu Provincial Hospital of TCM,Lanzhou 730050,Gansu,China
關(guān)鍵詞:
椎間盤移位;  腰椎;  獨活寄生湯;  椎間盤切除術(shù); 經(jīng)皮;  術(shù)后殘余癥狀;  專題Meta分析
Keywords:
intervertebral disc displacement;  lumbar vertebrae;  Duhuo Jisheng decoction;  diskectomy; percutaneous;  postoperative residual symptoms;  meta-analysis as topic
摘要:
目的:評價口服獨活寄生湯治療經(jīng)皮內(nèi)窺鏡下腰椎間盤切除術(shù)(percutaneous endoscopic lumbar discectomy,PELD)后殘余癥狀的臨床療效。方法:應(yīng)用計算機檢索中國知網(wǎng)、維普網(wǎng)、萬方數(shù)據(jù)庫、中國生物醫(yī)學(xué)文獻(xiàn)服務(wù)系統(tǒng)、PubMed、Embase、Cochrane Library和Web of Science中關(guān)于口服獨活寄生湯治療PELD術(shù)后殘余癥狀的隨機對照試驗文獻(xiàn),檢索時限為建庫至2021年7月1日。試驗組采用口服獨活寄生湯治療,也可聯(lián)合口服抗生素、口服甲鈷胺或常規(guī)康復(fù)治療; 對照組采用口服抗生素、口服甲鈷胺或常規(guī)康復(fù)治療。由2名研究者獨立檢索、篩選文獻(xiàn),提取資料,并采用Cochrane偏倚風(fēng)險評估工具對納入文獻(xiàn)的質(zhì)量及偏倚風(fēng)險進行評估。采用RevMan5.3軟件進行Meta分析。結(jié)果:共檢索出49篇相關(guān)文獻(xiàn),通過逐層篩選,最終納入8篇文獻(xiàn),均為中文文獻(xiàn),共涉及700例患者,其中試驗組351例、對照組349例。Meta分析結(jié)果顯示,試驗組患者腰腿部疼痛視覺模擬量表評分、腰椎Oswestry功能障礙指數(shù)評分均低于對照組[MD=-0.77,95%CI(-0.94,-0.59),P =0.000; MD=-7.98,95%CI(-9.10,-6.86),P=0.000],試驗組患者日本骨科協(xié)會腰痛疾患療效評分、尼龍繩試驗評分均高于對照組[MD=3.51,95%CI(2.74,4.28),P=0.000; MD=1.96,95%CI(1.64,2.28),P=0.000]。結(jié)論:現(xiàn)有的證據(jù)表明,口服獨活寄生湯可以緩解PELD術(shù)后的腰腿部疼痛及下肢麻木、無力等癥狀,改善腰椎功能。
Abstract:
Objective:To evaluate the clinical outcomes of oral application of Duhuo Jisheng Tang(獨活寄生湯,DHJST)for treatment of residual symptoms emerged after percutaneous endoscopic lumbar discectomy(PELD).Methods:All the randomized controlled trial(RCT)articles about oral application of DHJST for treatment of residual symptoms emerged after PELD included from database establishing to July 1,2021 were retrieved from the China National Knowledge Internet,Vip Database,Wanfang Database,Chinese Biomedical Literature Service System,PubMed,Embase,Cochrane Library and Web of Science through computer.The patients in experimental group were treated with oral application of DHJST,or combined with oral application of antibiotics,oral application of mecobalamine or conventional rehabilitation therapy; while the ones in control group with oral application of antibiotics,oral application of mecobalamine or conventional rehabilitation therapy alone.The articles were retrieved and screened and the information was extracted independently by two researchers according to the inclusion and exclusion criteria,and if any disagreement was found between them,discussion was conducted or asked for another researcher for making a final decision.The methodological quality and bias risk of research in the articles was evaluated by using Cochrane bias risk assessment tools,and then a Meta-analysis was conducted by using RevMan5.3 software.Results:Forty-nine articles were searched out.After screening,8 Chinese articles(700 patients)were included in the final analysis,351 patients in experimental group and 349 ones in control group.The results of Meta-analysis revealed that the lumbago-leg pain visual analogue scale(VAS)scores and lumbar Oswestry disability index(ODI)scores were lower,while the Japanese Orthopaedic Association(JOA)low back pain efficacy scores and Nylon rope test scores were higher in experimental group compared to control group(MD=-0.77,95%CI(-0.94,-0.59),P =0.000; MD=-7.98,95%CI(-9.10,-6.86),P=0.000; MD=3.51,95%CI(2.74,4.28),P=0.000; MD=1.96,95%CI(1.64,2.28),P=0.000).Conclusion:Available evidences suggest that oral application of DHJST can relieve the residual symptoms such as lumbar-leg pain,lower limbs numbness-weakness and improve the lumbar function in patients who undergo PELD.

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備注/Memo

備注/Memo:
基金項目:甘肅省科技計劃項目(21JR1RA058); 蘭州市人才創(chuàng)新創(chuàng)業(yè)項目(2020-RC-54) 通訊作者:王想福 E-mail:[email protected]
更新日期/Last Update: 1900-01-01