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[1]張維新,童培建.干細(xì)胞移植治療股骨頭壞死的研究進(jìn)展[J].中醫(yī)正骨,2019,31(05):28-30.
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干細(xì)胞移植治療股骨頭壞死的研究進(jìn)展()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第31卷
期數(shù):
2019年05期
頁(yè)碼:
28-30
欄目:
綜 述
出版日期:
2019-05-20

文章信息/Info

作者:
張維新1; 童培建2
(1.浙江中醫(yī)藥大學(xué)第一臨床醫(yī)學(xué)院,浙江 杭州 310006; 2.浙江省中醫(yī)院,浙江 杭州 310006)
關(guān)鍵詞:
股骨頭壞死;  干細(xì)胞移植;  骨髓間充質(zhì)干細(xì)胞;  脂肪干細(xì)胞;  綜述
摘要:
股骨頭壞死的發(fā)病目前呈現(xiàn)出年輕化的趨勢(shì),包括干細(xì)胞移植在內(nèi)的各種保髖療法成為了研究的熱點(diǎn)。骨髓間充質(zhì)干細(xì)胞和脂肪干細(xì)胞在股骨頭壞死的治療中應(yīng)用最為廣泛,常用的治療方式包括經(jīng)血管灌注、經(jīng)皮置管灌注及髓芯減壓灌注。干細(xì)胞移植主要是通過(guò)其旁分泌作用、增殖能力、分化能力,促進(jìn)壞死區(qū)骨組織再生、血管再生,從而緩解髖關(guān)節(jié)癥狀、延緩股骨頭壞死進(jìn)程。對(duì)于干細(xì)胞移植治療股骨頭壞死作用機(jī)制、細(xì)胞種類(lèi)、細(xì)胞濃度及療程的研究,將有助于進(jìn)一步提高該療法的療效和安全性。

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更新日期/Last Update: 2019-05-20