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[1]董根榮,陳龍,何斌,等.加味桃紅四物湯對老年股骨轉(zhuǎn)子間骨折股骨近端防旋髓內(nèi)釘內(nèi)固定術(shù)圍手術(shù)期隱性失血的影響[J].中醫(yī)正骨,2017,29(09):12-14，22.
　DONG Genrong,CHEN Long,HE Bin,et al.Influence of Jiawei Taohong Siwu Tang(加味桃紅四物湯)on perioperative hidden blood loss in aged patients who received proximal femoral nail antirotation internal fixation for femoral intertrochanteric fractures[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(09):12-14，22.
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加味桃紅四物湯對老年股骨轉(zhuǎn)子間骨折股骨近端防旋髓內(nèi)釘內(nèi)固定術(shù)圍手術(shù)期隱性失血的影響()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第29卷
期數(shù):
2017年09期
頁碼:
12-14，22
欄目:
臨床研究
出版日期:
2017-09-20

文章信息/Info

Title:
Influence of Jiawei Taohong Siwu Tang(加味桃紅四物湯)on perioperative hidden blood loss in aged patients who received proximal femoral nail antirotation internal fixation for femoral intertrochanteric fractures
作者:
董根榮; 陳龍; 何斌; 堯彥青; 沈衛(wèi)東
浙江省湖州市南潯區(qū)人民醫(yī)院,浙江 湖州 313009
Author(s):
DONG Genrong; CHEN Long; HE Bin; YAO Yanqing; SHEN Weidong
Nanxun People's Hospital of Huzhou City,Huzhou 313009,Zhejiang,China
關鍵詞:
失血; 手術(shù);  隱性失血;  髖骨折;  桃紅四物湯;  骨折固定術(shù); 髓內(nèi);  股骨近端防旋髓內(nèi)釘;  靜脈血栓形成;  臨床試驗
Keywords:
Key words blood loss; surgical;  hidden blood loss;  hip fractures;  Taohong Siwu Tang;  fracture fixation; intramedullary;  proximal femoral nail antirotation;  venous thrombosis;  clinical trial
摘要:
目的:探討圍手術(shù)期應用加味桃紅四物湯對老年股骨轉(zhuǎn)子間骨折股骨近端防旋髓內(nèi)釘(proximal femoral nail antirotation,PFNA)內(nèi)固定術(shù)圍手術(shù)期隱性失血的影響及其安全性。方法:將78例老年股骨轉(zhuǎn)子間骨折患者隨機分為加味桃紅四物湯組(38例)和常規(guī)治療組(40例)。所有患者均由同一組醫(yī)生完成PFNA內(nèi)固定手術(shù),術(shù)后12 h開始皮下注射低分子量肝素注射液,每天1次,連用7 d。加味桃紅四物湯組自入院2 h后即口服加味桃紅四物湯,直至術(shù)后第7 天,手術(shù)日停服1次。常規(guī)治療組除不口服加味桃紅四物湯外,其余治療均與加味桃紅四物湯組相同。測定2組患者的失血量,術(shù)后7 d時通過超聲檢查觀察下肢靜脈血栓形成情況。結(jié)果:加味桃紅四物湯組的失血總量和術(shù)后隱性失血量均低于常規(guī)治療組[(1 240.0±297.0)mL,(1 475.0±300.0)mL,t=-124.637,P=0.000;(797.0±290.0)mL,(988.0±288.0)mL,t=-80.898,P=0.000]; 2組患者顯性失血量和術(shù)前隱性失血量比較,組間差異均無統(tǒng)計學意義[(359.0±65.0)mL,(357.0±58.0)mL,t=1.698,P=0.000;(157.0±41.3)mL,(159.0±40.4)mL,t=-1.829,P=0.068]。術(shù)后7 d時常規(guī)治療組1例患者出現(xiàn)股靜脈栓塞,加味桃紅四物湯組未發(fā)現(xiàn)下肢靜脈血栓。2組患者的下肢靜脈血栓發(fā)生率比較,差異無統(tǒng)計學意義(P=1.000)。結(jié)論:圍手術(shù)期應用加味桃紅四物湯可有效減少老年股骨轉(zhuǎn)子間骨折PFNA內(nèi)固定術(shù)圍手術(shù)期隱性失血,并且具有較高的安全性。
Abstract:
ABSTRACT Objective:To explore the influence of Jiawei Taohong Siwu Tang(加味桃紅四物湯,JWTHSWT)on perioperative hidden blood loss in aged patients who received proximal femoral nail antirotation(PFNA)internal fixation for femoral intertrochanteric fractures and its safety.Methods:Seventy-eight aged patients with femoral intertrochanteric fractures were randomly divided into JWTHSWT group(38 cases)and conventional therapy group(40 cases).All patients were treated with PFNA internal fixation by the same group of surgeons and with subcutaneous injection of low-molecular-weight heparin since the 12th hour after the surgery,once a day for consecutive 7 days.Meanwhile,the patients in JWTHSWT group were treated with oral application of JWTHSWT from the 2nd hour after hospitalization admission till postoperative day 7 except on the day of surgery.The blood loss were measured and compared between the 2 groups,and the incidences of lower limb venous thrombosis were also observed through ultrasonic examination on postoperative day 7.Results:The total blood loss and postoperative hidden blood loss were lower in JWTHSWT group compared to conventional therapy group(1 240.0+/-297.0 vs 1 475.0+/-300.0 ml,t=-124.637,P=0.000; 797.0+/-290.0 vs 988.0+/-288.0 ml,t=-80.898,P=0.000).There was no statistical difference in dominant blood loss and preoperative hidden blood loss between the 2 groups(359.0+/-65.0 vs 357.0+/-58.0 ml,t=1.698,P=0.000; 157.0+/-41.3 vs 159.0+/-40.4 ml,t=-1.829,P=0.068).The femoral venous embolism(1 case)were found on postoperative day 7 in conventional therapy group,and no lower limb venous thrombosis was found in JWTHSWT group.There was no statistical difference in the incidence rate of lower limb venous thrombosis between the 2 groups(P=1.000).Conclusion:Oral application of JWTHSWT in perioperative period can effectively reduce the perioperative hidden blood loss in aged patients who received PFNA internal fixation for femoral intertrochanteric fractures,and it has high safety.

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備注/Memo

備注/Memo:
通訊作者:董根榮 E-mail:[email protected]
更新日期/Last Update: 2018-02-23