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[1]龔家川.影響強(qiáng)直性脊柱炎患者髖關(guān)節(jié)受累的危險因素分析[J].中醫(yī)正骨,2017,29(06):25-27.
　GONG Jiachuan.Analysis of risk factors for affection of hip joint in patients with ankylosing spondylitis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(06):25-27.
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影響強(qiáng)直性脊柱炎患者髖關(guān)節(jié)受累的危險因素分析()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第29卷
期數(shù):
2017年06期
頁碼:
25-27
欄目:
臨床研究
出版日期:
2017-06-20

文章信息/Info

Title:
Analysis of risk factors for affection of hip joint in patients with ankylosing spondylitis
作者:
龔家川
河南省商丘市第一人民醫(yī)院,河南 商丘 476100
Author(s):
GONG Jiachuan
The First People's Hospital of Shangqiu,Shangqiu 476100,Henan,China
關(guān)鍵詞:
脊柱炎; 強(qiáng)直性;  髖關(guān)節(jié);  危險因素
Keywords:
Key words spondylitis; ankylosing;  hip joint;  risk factors
摘要:
目的:探討影響強(qiáng)直性脊柱炎(ankylosing spondylitis,AS)患者髖關(guān)節(jié)受累的危險因素,為臨床早期干預(yù)提供依據(jù)。方法:回顧性分析94例AS患者的臨床資料,根據(jù)髖關(guān)節(jié)是否受累分為髖關(guān)節(jié)受累組(36例)和髖關(guān)節(jié)未受累組(58例)。觀察受累髖關(guān)節(jié)的具體情況,并比較2組患者的發(fā)病年齡、紅細(xì)胞沉降率(erythrocyte sedimentation rate,ESR)、血清C反應(yīng)蛋白(C-reactive protein,CRP)含量、血清免疫球蛋白G(immunoglobulin G,IgG)含量、Schober試驗(yàn)值及枕墻距。結(jié)果:36例髖關(guān)節(jié)受累患者中,單側(cè)髖關(guān)節(jié)受累7例、雙側(cè)髖關(guān)節(jié)受累29例,其中37個股骨頭囊性變、26個股骨頭壞死、21個髖關(guān)節(jié)間隙變窄、8個髖關(guān)節(jié)纖維性強(qiáng)直或骨性強(qiáng)直。與髖關(guān)節(jié)未受累組相比,髖關(guān)節(jié)受累組的發(fā)病年齡低、ESR高、血清CRP含量和IgG含量高、Schober試驗(yàn)值低、枕墻距大[(21.3±2.7)歲,(31.5±5.0)歲,t=5.584,P=0.028;(47.7±29.4)mm·h-1,(31.6±12.7)mm·h-1,t=5.692,P=0.024;(52.8±31.5)mg·L-1,(33.2±23.6)mg·L-1,t=7.013,P=0.015;(29.8±10.2)g·L-1,(14.9±7.2)g·L-1,t=8.826,P=0.009;(2.4±0.9)cm,(3.2±0.7)cm,t=4.942,P=0.039;(16.3±4.4)cm,(10.2±3.8)cm,t=6.975,P=0.018]。結(jié)論:發(fā)病年齡低、ESR高、血清CRP含量和IgG含量高、Schober試驗(yàn)值低、枕墻距大,均可能是影響AS患者髖關(guān)節(jié)受累的危險因素。
Abstract:
ABSTRACT Objective:To explore the risk factors for affection of hip joint in patients with ankylosing spondylitis(AS)so as to provide evidence for early clinical intervention.Methods:The medical records of 94 patients with AS were analyzed retrospectively,and the patients were divided into affected hip joint group(36 cases)and unaffected hip joint group(58 cases).The affected hip joints were observed and the age of onset,erythrocyte sedimentation rate(ESR),the serum content of C-reactive protein(CRP)and immunoglobulin G(IgG),Schober values and pillow-wall distance were compared between the 2 groups.Results:Unilateral affected hip joint(7 cases)and bilateral affected hip joint(29 cases)were found in 36 patients.The hip joint damages included cystis degeneration of femoral head(37),femoral head necrosis(26),narrowed hip joint space(21)and fibrous ankylosis or bony ankylosis of hip joint(8).Compared with patients in unaffected hip joint group,patients in affected hip joint group had a lower onset age,higher ESR,higher serum contents of CRP and IgG,lower Schober values and longer pillow-wall distance(21.3+/-2.7 vs 31.5+/-5.0 years,t=5.584,P=0.028; 47.7+/-29.4 vs 31.6+/-12.7mm/h,t=5.692,P=0.024; 52.8+/-31.5 vs 33.2+/-23.6 mg/L,t=7.013,P=0.015; 29.8+/-10.2 vs 14.9+/-7.2g/L,t=8.826,P=0.009; 2.4+/-0.9 vs 3.2+/-0.7 cm,t=4.942,P=0.039; 16.3+/-4.4 vs 10.2+/-3.8 cm,t=6.975,P=0.018).Conclusion:Lower onset age,higher ESR,higher serum contents of CRP and IgG,lower Schober experimental values and longer pillow-wall distance may be risk factors for affection of hip joint in patients with AS.

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更新日期/Last Update: 2017-06-20