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[1]鞠昌軍,嚴(yán)偉,姜紅江,等.自體細(xì)胞生長(zhǎng)因子關(guān)節(jié)腔注射聯(lián)合佩戴人工膝關(guān)節(jié)支具治療膝骨關(guān)節(jié)炎[J].中醫(yī)正骨,2016,28(09):46-48.
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自體細(xì)胞生長(zhǎng)因子關(guān)節(jié)腔注射聯(lián)合佩戴人工膝關(guān)節(jié)支具治療膝骨關(guān)節(jié)炎()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第28卷
期數(shù):
2016年09期
頁(yè)碼:
46-48
欄目:
膝骨關(guān)節(jié)炎
出版日期:
2016-09-20

文章信息/Info

作者:
鞠昌軍嚴(yán)偉姜紅江高廣凌宋修剛秦立武
山東省文登整骨醫(yī)院,山東 文登 264400
關(guān)鍵詞:
骨關(guān)節(jié)炎 注射關(guān)節(jié)內(nèi) 自體細(xì)胞生長(zhǎng)因子 體外人工膝關(guān)節(jié)
摘要:
目的:觀察自體細(xì)胞生長(zhǎng)因子關(guān)節(jié)腔注射聯(lián)合佩戴人工膝關(guān)節(jié)支具治療膝骨關(guān)節(jié)炎的臨床療效及安全性。方法:2014年6月至2015年3月,采用自體細(xì)胞生長(zhǎng)因子關(guān)節(jié)腔注射聯(lián)合佩戴人工膝關(guān)節(jié)支具治療膝骨關(guān)節(jié)炎患者36例,男8例、女28例。年齡49~67歲,中位數(shù)55歲。病程4~24個(gè)月,中位數(shù)15.5個(gè)月。分別于治療前及治療開始后1 d、1個(gè)月、3個(gè)月、6個(gè)月測(cè)定患者的西安大略和麥克馬斯特大學(xué)(Western Ontario and McMaster Universities,WOMAC)骨關(guān)節(jié)炎指數(shù)評(píng)分,比較治療前及治療開始后6個(gè)月的膝關(guān)節(jié)內(nèi)側(cè)脛股關(guān)節(jié)間隙寬度,觀察不良反應(yīng)和并發(fā)癥發(fā)生情況。結(jié)果:所有患者均獲隨訪,隨訪時(shí)間6~12個(gè)月,中位數(shù)8個(gè)月。治療及隨訪過(guò)程中均未出現(xiàn)任何不良反應(yīng)和并發(fā)癥。WOMAC骨關(guān)節(jié)炎指數(shù)評(píng)分,治療前(46.5±7.3)分,治療開始后1 d(40.4±6.5)分、1個(gè)月(32.2±4.7)分、3個(gè)月(30.5±5.1)分、6個(gè)月(27.8±4.6)分。治療開始后6個(gè)月膝關(guān)節(jié)內(nèi)側(cè)脛股關(guān)節(jié)間隙寬度大于治療前[(2.2±0.6)mm,(3.3±0.5)mm,t=8.450,P=0.000]。結(jié)論:自體細(xì)胞生長(zhǎng)因子關(guān)節(jié)腔注射聯(lián)合佩戴人工膝關(guān)節(jié)支具治療膝骨關(guān)節(jié)炎,能夠有效改善膝關(guān)節(jié)功能、增大內(nèi)側(cè)脛股關(guān)節(jié)間隙,且安全性好,值得臨床推廣應(yīng)用。

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備注/Memo

備注/Memo:
2016-05-04收稿 2016-07-16修回
基金項(xiàng)目:山東省威海市科技發(fā)展計(jì)劃項(xiàng)目(2015GNS048)
姜紅江 E-mail:[email protected]

更新日期/Last Update: 1900-01-01