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[1]劉卓,李益亮,張志,等.Notch4受體對血管新生的影響[J].中醫(yī)正骨,2016,28(06):56-58.
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Notch4受體對血管新生的影響()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第28卷
期數(shù):
2016年06期
頁碼:
56-58
欄目:
綜述
出版日期:
2016-06-20

文章信息/Info

作者:
劉卓李益亮張志孫紹裘
湖南中醫(yī)藥大學(xué)第二附屬醫(yī)院,湖南 長沙 410005
關(guān)鍵詞:
受體Notch 信號傳導(dǎo) 血管新生 綜述
摘要:
血管新生是創(chuàng)傷修復(fù)的重要病理過程,Notch信號通路對其具有關(guān)鍵性的調(diào)控作用,而Notch4受體是Notch受體中特異性分布在血管內(nèi)皮并且是分布在毛細(xì)血管內(nèi)皮上的唯一受體。Notch4受體信號通路可促進(jìn)血管新生; Notch4受體的正常表達(dá)是血管正常發(fā)育的必備條件,過度表達(dá)則可致血管發(fā)育缺陷,表達(dá)不足時可與Notch1受體相互代償。本文對Notch4受體對血管新生的影響進(jìn)行了綜述。

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備注/Memo

備注/Memo:
基金項(xiàng)目:國家自然科學(xué)基金項(xiàng)目(81373658)
通訊作者:孫紹裘 E-mial:[email protected]
更新日期/Last Update: 2016-06-30