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[1]喻秋萍,唐萌芽,王崢峰,等.身痛逐瘀湯治療腰椎間盤突出癥的系統(tǒng)評(píng)價(jià)[J].中醫(yī)正骨,2016,28(06):24-27.
　YU Qiuping,TANG Mengya,WANG Zhengfeng,et al.Efficacy of Shentong Zhuyu Tang(身痛逐瘀湯)for treatment of lumbar disc herniation:a systematic review[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2016,28(06):24-27.
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身痛逐瘀湯治療腰椎間盤突出癥的系統(tǒng)評(píng)價(jià)()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第28卷
期數(shù):
2016年06期
頁碼:
24-27
欄目:
文獻(xiàn)研究
出版日期:
2016-06-20

文章信息/Info

Title:
Efficacy of Shentong Zhuyu Tang(身痛逐瘀湯)for treatment of lumbar disc herniation:a systematic review
作者:
喻秋萍; 唐萌芽; 王崢峰; 王勇
浙江省杭州市富陽中醫(yī)骨傷醫(yī)院,浙江 杭州 311400
Author(s):
YU Qiuping; TANG Mengya; WANG Zhengfeng; WANG Yong
Fuyang TCM Orthopedic-Traumatological Hospital,Hangzhou 311400,Zhejiang,China
關(guān)鍵詞:
身痛逐瘀湯;  椎間盤移位;  腰痛;  腰腿痛;  臨床試驗(yàn);  Meta分析;  綜述
Keywords:
Shentong Zhuyu Tang;  intervertebral disc displacement;  low back pain;  lumbago-leg pain;  clinical trail;  meta-analysis;  review
摘要:
目的:系統(tǒng)評(píng)價(jià)身痛逐瘀湯治療腰椎間盤突出癥(lumbar disc herniation,LDH)的臨床療效。方法:分別以“腰椎間盤突出”“腰椎間盤膨出”“腰椎間盤脫出”“腰椎間盤移位”“腰痛”“腰腿痛”“LDH”與“身痛逐瘀湯”的布爾邏輯搭配結(jié)果作為檢索詞,運(yùn)用計(jì)算機(jī)檢索中國(guó)知網(wǎng)、萬方學(xué)術(shù)期刊數(shù)據(jù)庫和維普中文期刊數(shù)據(jù)庫2000年1月至2016年3月收錄的所有相關(guān)文獻(xiàn)。篩選文獻(xiàn),提取數(shù)據(jù),利用Revman5.1軟件進(jìn)行數(shù)據(jù)統(tǒng)計(jì)分析。結(jié)果:共檢索出116篇文獻(xiàn),經(jīng)篩選最終納入17篇,共涉及1929例患者。所納入文獻(xiàn)質(zhì)量偏低,僅3篇文獻(xiàn)說明采用隨機(jī)數(shù)字表進(jìn)行分組,2篇文獻(xiàn)說明了隨訪情況和安全性評(píng)價(jià)結(jié)果,所有文獻(xiàn)均未描述隨機(jī)分配方案的隱藏方法、是否采用盲法、樣本量估算方法及病例脫落情況,Jadad評(píng)分≤2分。納入的17篇文獻(xiàn)均進(jìn)行了2組間臨床療效有效率的比較,各研究結(jié)果之間具有同質(zhì)性(I2=0%,P=0.900)。治療組的有效率高于對(duì)照組[Z=8.320,P=0.000; OR=2.300,95%CI(1.89,2.79)]。漏斗圖顯示試驗(yàn)研究分布在豎線的兩邊,分布較為均勻,不存在發(fā)表偏倚。結(jié)論:身痛逐瘀湯單獨(dú)使用或聯(lián)合其他療法均能有效緩解LDH患者的臨床癥狀,療效優(yōu)于西藥、推拿、牽引等治療。但由于納入的文獻(xiàn)在方法學(xué)上存在不足,該結(jié)論尚有一定的局限性,有待于更多的高質(zhì)量的臨床隨機(jī)對(duì)照試驗(yàn)進(jìn)一步證實(shí)。
Abstract:
Objective:To systematically review the clinical curative effect of Shentong Zhuyu Tang(身痛逐瘀湯,STJYT)in the treatment of lumbar disc herniation(LDH).Methods:The Boolean logical combination of lumbar disc herniation,lumbar disc bulging,lumbar disc prolapse,lumbar disc displacement,low back pain,lumbago-leg pain,LDH and STJYT were used as index terms respectively to retrieve all the literatures included from January 2000 to March 2016 from China national knowledge internet,Wanfang Database and Vip Database of Chinese journal through computer.The literatures were screened and the data were extracted.Statistical analysis was conducted by using Revman 5.1 software.Results:One hundred and sixteen literatures were searched out.After screening,17 literatures(1929 patients)were included in the final analysis,however,the quality of these literatures was poor.The random digits table was used for grouping only in 3 literatures,and only 2 literatures showed the results of follow-up and safety evaluation.The included literatures failed to report the method for random allocation concealment,the blind method,method for sample size estimation and information about case drop-out.The Jadad scores of included literatures were less than or equal to 2 points.The effective rate of clinical curative effect was compared between the 2 groups in all of the 17 literatures and there was homogeneity within the results of different trials(I2=0%,P=0.900).The effective rate of treatment group was higher than that of control group(Z=8.320,P=0.000; OR=2.300,95%CI(1.89,2.79)).The symmetrical funnel plot demonstrated that there was no publication bias.Conclusion:Both STJYT alone and combination of STJYT with other therapies can effectively relieve the clinical symptoms in patients with LDH,and they surpass western medicine,lumbar manipulation and lumbar traction in the clinical curative effect.However,the included literatures have shortcomings in methodology,so our conclusion has some limitations and need to be further verified by more high-quality clinical randomized controlled trials.

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通訊作者:喻秋萍 E-mail:[email protected]
更新日期/Last Update: 2016-06-30