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[1]倪力剛,胡勁濤.關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸與單純關(guān)節(jié)鏡清理術(shù)治療 早期膝骨關(guān)節(jié)炎的對比研究[J].中醫(yī)正骨,2015,27(12):41-45.
 NI Ligang,HU Jintao.A retrospective trial of arthroscopic debridement integrated and nonintegrated with Chinese herbal steaming for treatment of early knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(12):41-45.
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關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸與單純關(guān)節(jié)鏡清理術(shù)治療 早期膝骨關(guān)節(jié)炎的對比研究()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第27卷
期數(shù):
2015年12期
頁碼:
41-45
欄目:
臨床研究
出版日期:
2015-12-30

文章信息/Info

Title:
A retrospective trial of arthroscopic debridement integrated and nonintegrated with Chinese herbal steaming for treatment of early knee osteoarthritis
作者:
倪力剛1胡勁濤2
1.浙江省杭州市余杭區(qū)第五人民醫(yī)院,浙江 杭州 311100;
2.浙江省紹興市柯橋區(qū)中醫(yī)醫(yī)院,浙江 紹興 312030
Author(s):
NI Ligang1HU Jintao2
1.The Fifth People's Hospital of Yuhang district in Hangzhou City,Hangzhou 311100,Zhejiang,China
2.Keqiao Hospital of Traditional Chinese Medicine in Shaoxing City,Shaoxing 312030,Zhejiang,China
關(guān)鍵詞:
骨關(guān)節(jié)炎 關(guān)節(jié)鏡檢查 薰洗 治療臨床研究性
Keywords:
osteoarthritisknee arthroscopy steaming washing therapy therapiesinvestigational
摘要:
目的:比較關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸與單純關(guān)節(jié)鏡清理術(shù)治療早期膝骨關(guān)節(jié)炎的臨床療效。方法:回顧性分析64例早期膝骨關(guān)節(jié)炎患者的病例資料,其中采用單純關(guān)節(jié)鏡清理術(shù)治療35例,采用關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸治療29例。男26例,女38例。年齡53~67歲,中位數(shù)59歲。按照骨關(guān)節(jié)炎Kellgren-Lawrence影像學(xué)分級,Ⅰ級22例、Ⅱ級42例。分別比較術(shù)前、術(shù)后6個月及術(shù)后12個月時2組患者的膝關(guān)節(jié)疼痛視覺模擬量表(visual analogue scale,VAS)評分、健康調(diào)查簡表(36-item short form health survey,SF-36)評分及Lysholm膝關(guān)節(jié)評分。結(jié)果:手術(shù)前后不同時間點(diǎn)膝關(guān)節(jié)疼痛VAS評分比較,差異有統(tǒng)計學(xué)意義,存在時間效應(yīng)(F=1032.375,P=0.000); 2組患者膝關(guān)節(jié)疼痛VAS評分比較,組間差異有統(tǒng)計學(xué)意義,存在分組效應(yīng)(F=6.772,P=0.012); 術(shù)前2組患者膝關(guān)節(jié)疼痛VAS評分比較,差異無統(tǒng)計學(xué)意義[(8.2±0.8)分,(8.3±0.7)分,t=0.354,P=0.554]; 術(shù)后6個月和術(shù)后12個月,關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸組的膝關(guān)節(jié)疼痛VAS評分均低于單純關(guān)節(jié)鏡清理術(shù)組[(1.2±1.0)分,(1.9±1.0)分,t=7.512,P=0.008;(2.0±1.0)分,(2.6±1.0)分,t=4.326,P=0.042]; 時間因素和分組因素存在交互效應(yīng)(F=3.567,P=0.031)。手術(shù)前后不同時間點(diǎn)SF-36評分比較,差異有統(tǒng)計學(xué)意義,存在時間效應(yīng)(F=2501.188,P=0.000); 2組患者SF-36評分比較,組間差異有統(tǒng)計學(xué)意義,存在分組效應(yīng)(F=40.308,P=0.000); 術(shù)前2組患者SF-36評分比較,差異無統(tǒng)計學(xué)意義[(55.5±3.6)分,(56.0±3.7)分,t=0.363,P=0.549]; 術(shù)后6個月和術(shù)后12個月,關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸組的SF-36評分均高于單純關(guān)節(jié)鏡清理術(shù)組[(91.7±3.0)分,(87.9±2.9)分,t=25.938,P=0.000;(88.8±2.6)分,(83.7±3.2)分,t=55.254,P=0.000]; 時間因素和分組因素存在交互效應(yīng)(F=9.868,P=0.000)。手術(shù)前后不同時間點(diǎn)Lysholm膝關(guān)節(jié)評分比較,差異有統(tǒng)計學(xué)意義,存在時間效應(yīng)(F=1980.728,P=0.000); 2組患者Lysholm膝關(guān)節(jié)評分比較,組間差異有統(tǒng)計學(xué)意義,存在分組效應(yīng)(F=39.257,P=0.000); 術(shù)前2組患者Lysholm膝關(guān)節(jié)評分比較,差異無統(tǒng)計學(xué)意義[(52.3±3.8)分,(52.3±3.7)分,t=0.004,P=0.950]; 術(shù)后6個月和術(shù)后12個月,關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸組的Lysholm膝關(guān)節(jié)評分均高于單純關(guān)節(jié)鏡清理術(shù)組[(90.5±2.8)分,(87.0±3.2)分,t=20.987,P=0.000;(88.5±3.1)分,(82.8±4.3)分,t=35.725,P=0.000]; 時間因素和分組因素存在交互效應(yīng)(F=9.744,P=0.000)。結(jié)論:關(guān)節(jié)鏡清理術(shù)聯(lián)合中藥薰蒸治療早期KOA,能夠緩解或消除膝關(guān)節(jié)疼痛,改善膝關(guān)節(jié)功能,提高患者生活質(zhì)量,其療效優(yōu)于單純關(guān)節(jié)鏡清理術(shù),值得臨床推廣應(yīng)用。
Abstract:
Objective:To compare the clinical curative effects of combination therapy of arthroscopic debridement and Chinese herbal steaming versus monotherapy of arthroscopic debridement in the treatment of early knee osteoarthritis(KOA).Methods:The medical records of 64 patients with early KOA were analyzed retrospectively.Thirty-five patients were treated with monotherapy of arthroscopic debridement(monotherapy group)while the others were treated with combination therapy of arthroscopic debridement and Chinese herbal steaming(combination therapy group).The patients consisted of 26 males and 38 females,and ranged in age from 53 to 67 years(Median=59 yrs).According to Kellgren-Lawrence imaging classification,the KOA belonged to typesⅠ(22)andⅡ(42).The visual analogue scale (VAS)scores,36-item short form health survey(SF-36)scores and Lysholm knee scores were compared between the 2 groups before the surgery and at 6 and 12 months after the surgery respectively.Results:There was statistical difference in the knee pain VAS scores between different time points,in other words,there was time effect(F=1032.375,P=0.000).There was statistical difference in the knee pain VAS scores between the two groups,in other words,there was group effect(F=6.772,P=0.012).There was no statistical difference in preoperative knee pain VAS scores between the 2 groups(8.2+/-0.8 vs 8.3+/-0.7 points,t=0.354,P=0.554).The knee pain VAS scores were lower in combination therapy group compared to monotherapy group at 6 and 12 months after the surgery(1.2+/-1.0 vs 1.9+/-1.0 points,t=7.512,P=0.008; 2.0+/-1.0 vs 2.6+/-1.0 points,t=4.326,P=0.042).There was interaction between time factor and group factor(F=3.567,P=0.031).There was statistical difference in the SF-36 scores between different time points,in other words,there was time effect(F=2501.188,P=0.000).There was statistical difference in the SF-36 scores between the two groups,in other words,there was group effect(F=40.308,P=0.000).There was no statistical difference in preoperative SF-36 scores between the 2 groups(55.5+/-3.6 vs 56.0+/-3.7 points,t=0.363,P=0.549).The SF-36 scores were higher in combination therapy group compared to monotherapy group at 6 and 12 months after the surgery(91.7+/-3.0 vs 87.9+/-2.9 points,t=25.938,P=0.000; 88.8±2.6 vs 83.7±3.2 points,t=55.254,P=0.000).There was interaction between time factor and group factor(F=9.868,P=0.000).There was statistical difference in the Lysholm knee scores between different time points,in other words,there was time effect(F=1980.728,P=0.000).There was statistical difference in the Lysholm knee scores between the two groups,in other words,there was group effect(F=39.257,P=0.000).There was no statistical difference in preoperative Lysholm knee scores between the 2 groups(52.3+/-3.8 vs 52.3+/-3.7 points,t=0.004,P=0.950).The Lysholm knee scores were higher in combination therapy group compared to monotherapy group at 6 and 12 months after the surgery(90.5+/-2.8 vs 87.0+/-3.2 points,t=20.987,P=0.000; 88.5+/-3.1 vs 82.8+/-4.3 points,t=35.725,P=0.000).There was interaction between time factor and group factor(F=9.744,P=0.000).Conclusion:The combination therapy of arthroscopic debridement and Chinese herbal steaming can relieve or eliminate the knee pain and improve the knee function and the quality of live of patients with early KOA,and it surpasses the monotherapy of arthroscopic debridement in curative effect,so it is worthy of popularizing in clinic.

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備注/Memo

備注/Memo:
2015-10-07收稿 2015-11-18修回
通訊作者:倪力剛 E-mail:[email protected]
更新日期/Last Update: 2015-12-30