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[1]洪海平,王韜,謝燕,等.石氏針刺療法配合口服益腎蠲痹丸治療膝骨關(guān)節(jié)炎[J].中醫(yī)正骨,2015,27(05):5-8.
　HONG Haiping,WANG Tao,XIE Yan,et al.Combination therapy of Shi's acupuncture therapy and oral application of Yishen Juanbi Wan(益腎蠲痹丸)for the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(05):5-8.
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石氏針刺療法配合口服益腎蠲痹丸治療膝骨關(guān)節(jié)炎()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第27卷
期數(shù):
2015年05期
頁碼:
5-8
欄目:
臨床研究
出版日期:
2015-05-30

文章信息/Info

Title:
Combination therapy of Shi's acupuncture therapy and oral application of Yishen Juanbi Wan(益腎蠲痹丸)for the treatment of knee osteoarthritis
作者:
洪海平1; 王韜1; 謝燕1; 衛(wèi)曉恩2; 王俊龍2; 曹月龍2; 詹紅生2
1.上海中醫(yī)藥大學附屬曙光醫(yī)院松江分院,上海 201600;
2.上海中醫(yī)藥大學附屬曙光醫(yī)院,上海 200021
Author(s):
HONG Haiping1; WANG Tao1; XIE Yan1; WEI Xiaoen2; WANG Junlong2; CAO Yuelong2; ZHAN Hongsheng2
1.Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Songjiang branch,Shanghai 201600,China 2.Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China
關(guān)鍵詞:
骨關(guān)節(jié)炎; 膝;  針刺;  痹證;  中藥療法;  治療; 臨床研究性
Keywords:
osteoarthritis; knee;  acupuncture;  arthralgia syndrome;  drug therapy(TCD);  therapies; investigational
摘要:
目的:觀察石氏針刺療法配合口服益腎蠲痹丸治療膝骨關(guān)節(jié)炎的臨床療效和安全性。方法:將120例膝骨關(guān)節(jié)炎患者隨機分為2組,每組60例,分別采用石氏針刺療法配合口服益腎蠲痹丸和傳統(tǒng)針刺療法治療。于治療前和治療3周后,分別記錄并比較2組患者膝關(guān)節(jié)疼痛視覺模擬評分(vsual analogue score,VAS)及西安大略和麥克馬斯特大學(Western Ontario and McMaster Universities,WOMAC)量表積分; 并在治療期間觀察有無與治療相關(guān)的不良反應(yīng)。結(jié)果:治療3周后,3例患者脫落,其中石氏針刺療法配合口服益腎蠲痹丸組脫落1例,傳統(tǒng)針刺療法組脫落2例。治療前2組患者膝關(guān)節(jié)疼痛VAS評分及WOMAC量表積分比較,差異均無統(tǒng)計學意義[(7.14±1.14)分,(7.20±1.15)分,t=-0.180,P=0.858;(57.26±8.49)分,(56.36±8.76)分,t=0.404,P=0.688]。治療3周后,2組患者膝關(guān)節(jié)疼痛VAS評分[(2.90±1.47)分,(3.83±1.51)分]及WOMAC量表積分[(25.69±5.31)分,(34.90±4.75)分]均較治療前下降(t=11.559,P=0.000; t=9.505,P=0.000; t=13.319,P=0.000; t=9.627,P=0.000); 2組患者膝關(guān)節(jié)疼痛VAS評分下降幅度比較,差異無統(tǒng)計學意義[(4.18±1.95)分,(3.34±1.89)分,t=1.537,P=0.121]; 石氏針刺療法配合口服益腎蠲痹丸組膝關(guān)節(jié)WOMAC量表積分下降幅度大于傳統(tǒng)針刺療法組[(31.65±12.79)分,(21.86±12.22)分,t=2.830,P=0.006]。2組患者在治療期間均未出現(xiàn)不良反應(yīng)。結(jié)論:采用石氏針刺療法配合口服益腎蠲痹丸和傳統(tǒng)針刺療法治療KOA,均能緩解膝關(guān)節(jié)疼痛,不良反應(yīng)小; 但在改善膝關(guān)節(jié)功能方面,石氏針刺配合口服益腎蠲痹丸優(yōu)于傳統(tǒng)針刺療法,值得臨床推廣應(yīng)用。
Abstract:
Objective:To observe the clinical curative effect and safety of Shi's acupuncture therapy combined with oral application of Yishen Juanbi Wan(益腎蠲痹丸,YSJBW)for the treatment of knee osteoarthritis(KOA).Methods:One hundred and twenty patients with KOA were randomly divided into 2 groups,60 cases in each group.The patients were treated with Shi's acupuncture therapy combined with oral application of YSJBW(group A)and traditional acupuncture therapy(group B)respectively.The vsual analogue scores(VAS)and Western Ontario and McMaster Universities(WOMAC)scores were recorded and compared between the 2 groups before the treatment and after 3-week treatment respectively.The treatment-related adverse reactions were observed during the treatment.Results:Three patients(1 case in group A and 2 cases in group B)dropped out after 3-week treatment.There was no statistical difference in knee pain VAS scores and WOMAC scores between the 2 groups before the treatment(7.14+/-1.14 vs 7.20+/-1.15 points,t=-0.180,P=0.858; 57.26+/-8.49 vs 56.36+/-8.76 points,t=0.404,P=0.688).The knee pain VAS scores(2.90+/-1.47,3.83+/-1.51 points)and WOMAC scores(25.69+/-5.31,34.90+/-4.75 points)decreased in the 2 groups after 3-week treatment(t=11.559,P=0.000; t=9.505,P=0.000; t=13.319,P=0.000; t=9.627,P=0.000).There was no statistical difference in the descent degree of knee pain VAS scores----------------------------------------------- 基金項目:上海市衛(wèi)生局中醫(yī)藥科研基金項目(2012QL004A,2012L027B); 上海市松江區(qū)衛(wèi)生局醫(yī)學科研課題項目(2012-Ⅲ-36); 上海市松江區(qū)醫(yī)學特色專科建設(shè)項目(2013ZK01) 通訊作者:衛(wèi)曉恩 E-mail:[email protected] between the 2 groups(4.18+/-1.95 vs 3.34+/-1.89 points,t=1.537,P=0.121),while the knee-joint WOMAC scores decreased more significantly in group A compared to group B(31.65+/-12.79 vs 21.86+/-12.22 points,t=2.830,P=0.006).No adverse reactions were found in the 2 groups during the treatment period.Conclusion:Either Shi's acupuncture therapy combined with oral application of YSJBW or the traditional acupuncture therapy can relieve knee pain with less adverse reactions in the treatment of KOA.However,the former surpasses the latter in improving knee function,so it is worthy of popularizing in clinic.

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備注/Memo

備注/Memo:
2014-12-22收稿 2015-01-19修回
更新日期/Last Update: 2015-05-30