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[1]黃建華,黃建武,李慧輝,等.加味左歸丸對絕經(jīng)后骨質(zhì)疏松癥肝腎不足證 患者骨密度的影響[J].中醫(yī)正骨,2013,25(11):19-21.
 Huang Jianhua*,Huang Jianwu,Li Huihui,et al.Effect of JIAWEI ZUOGUI pill on bone mineral density in postmenopausal osteoporosis patients with deficiency of liver and kidney[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(11):19-21.
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加味左歸丸對絕經(jīng)后骨質(zhì)疏松癥肝腎不足證 患者骨密度的影響()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第25卷
期數(shù):
2013年11期
頁碼:
19-21
欄目:
臨床研究
出版日期:
2013-11-30

文章信息/Info

Title:
Effect of JIAWEI ZUOGUI pill on bone mineral density in postmenopausal osteoporosis patients with deficiency of liver and kidney
作者:
黃建華黃建武李慧輝李托
溫州醫(yī)科大學(xué)附屬第三醫(yī)院,浙江 瑞安 325200
Author(s):
Huang Jianhua*Huang JianwuLi HuihuiLiTuo.*
The Third Affiliated Hospital of Wenzhou Medical College,Rui'an 325200,Zhejiang,China
關(guān)鍵詞:
骨質(zhì)疏松絕經(jīng)后 加味左歸丸 骨密度 治療臨床研究性
Keywords:
Osteoporosis postmenopausal JIAWEI ZUOGUI pill Bone density Therapiesinvestigational
摘要:
目的:觀察加味左歸丸對絕經(jīng)后骨質(zhì)疏松癥肝腎不足證患者骨密度的影響。方法:將92例絕經(jīng)后骨質(zhì)疏松癥肝腎不足證患者隨機分為2組,治療組53例,對照組39例。治療組采用加味左歸丸治療,對照組采用骨康膠囊治療。比較2組患者的骨密度,臨床療效和不良反應(yīng)發(fā)生情況。結(jié)果:①骨密度。治療前2組患者骨密度比較,差異無統(tǒng)計學(xué)意義(t=0.727,P=0.469),治療后2組患者的骨密度均增加[(-3.58±0.79),(-2.19±0.67),t=9.769,P=0.000;(-3.71±0.92),(-3.21±0.49),t=2.996,P=0.004],治療組增加更明顯[(1.57±0.74),(1.24±0.65),t=2.224,P=0.029]。②臨床療效。治療組臨床控制33例、顯著進步8例、進步7例、無效5例,對照組臨床控制13例、顯著進步7例、進步10例、無效9例。治療組臨床療效優(yōu)于對照組。③不良反應(yīng)發(fā)生率。治療期間治療組3例患者出現(xiàn)腹脹、1例發(fā)生口腔潰瘍,對照組2例出現(xiàn)惡心癥狀,經(jīng)對癥處理后均治愈。結(jié)論:加味左歸丸能明顯增加絕經(jīng)后骨質(zhì)疏松癥肝腎不足證患者的骨密度,是治療該病的有效手段。
Abstract:
Objective:To observe the effect of JIAWEI ZUOGUI pill on bone mineral density(BMD)in postmenopausal osteoporosis patients with deficiency of liver and kidney.Methods:Ninety-two postmenopausal osteoporosis patients with deficiency of liver and kidney were randomly divided into 2 groups,53 cases in treatment group,while 39 cases in control group.Patients in treatment group were treated with JIAWEI ZUOGUI pill,while patients in control group were treated with GUKANG capsule.The BMD,clinical effects and complications were compared between the 2 groups.Results:There was no statistical difference in BMD between the 2 groups before the treatment(t=0.727,P=0.469),while the BMD increased in both of the 2 groups after the treatment(-3.58+/-0.79 vs -2.19+/-0.67,t=9.769,P=0.000; -3.71+/-0.92 vs -3.21+/-0.49,t=2.996,P=0.004),and the BMD increased more significantly in the treatment group(1.57+/-0.74 vs 1.24+/-0.65,t=2.224,P=0.029).Thirty-three patients obtained an excellent clinical curative effects,8 good,7 fair,and 5 poor in treatment group,while 13 cases obtained an excellent clinical curative effects,7 good,10 fair,and 9 poor in control group.Three patients with flatulence,2 patients with oral ulcer were found in the treatment group,while 2 patients with nausea symptom were found in the control group,which were all cured after treatment.Conclusion:The BMD of postmenopausal osteoporosis patients with deficiency of liver and kidney can be obviously increased by JIAWEI ZUOGUI pill,so it is the effective therapy to this disease.

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備注/Memo

備注/Memo:
2012-03-15收稿 2013-02-10修回
更新日期/Last Update: 2013-11-30