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[1]王平,盧啟貴,黃東紅,等.桃紅四妙湯結合低分子肝素鈣防治全膝關節(jié)置換術后深靜脈血栓形成的臨床觀察[J].中醫(yī)正骨,2012,24(01):27-31.
　WANG Ping*,LU Qi-gui,HUANG Dong-hong,et al.Clinical observation on the curative effect of TAOHONG SIMIAO DECOCTION combined with low molecular weight heparin calcium in the preventive treatment of deep vein thrombosis after total knee arthroplasty[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2012,24(01):27-31.
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桃紅四妙湯結合低分子肝素鈣防治全膝關節(jié)置換術后深靜脈 血栓形成的臨床觀察()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期數(shù):
2012年01期
頁碼:
27-31
欄目:
臨床研究
出版日期:
2012-01-31

文章信息/Info

Title:
Clinical observation on the curative effect of TAOHONG SIMIAO DECOCTION combined with low molecular weight heparin calcium in the preventive treatment of deep vein thrombosis after total knee arthroplasty
作者:
王平; 盧啟貴; 黃東紅; 孫克民; 李政; 裴代平; 高迪; 徐展
廣東省深圳平樂骨傷科醫(yī)院,廣東 深圳 518010
Author(s):
WANG Ping*; LU Qi-gui; HUANG Dong-hong; SUN Ke-min; LI Zheng; PEI Dai-ping; GAO Di; XU Zhan.
*Shenzhen Pingle Orthopedic Hospital,Shenzhen 518010,Guangdong,China
關鍵詞:
靜脈血栓形成 關節(jié)成形術; 置換; 膝 桃紅四妙湯 肝素; 低分子量 治療; 臨床研究性
Keywords:
Venous thrombosis;  Arthroplasty; replacement; knee;  TAOHONG SIMIAO DECOCTION;  Heparin; low-molecular-weight;  Therapies; investigational
摘要:
目的:探討桃紅四妙湯配合低分子肝素鈣防治全膝關節(jié)置換術后深靜脈血栓形成的臨床療效及安全性。方法:將符合要求的40例患者隨機分為治療組和對照組,每組20例。治療組采用桃紅四妙湯加低分子肝素鈣治療,對照組僅采用低分子肝素鈣治療。術后測定2組患者的患肢腫脹情況、凝血指標、血小板計數(shù)、切口引流量、血腫瘀斑及深靜脈血栓發(fā)生情況。結果:①患肢腫脹情況。大腿周徑:不同時間點周徑不全相同(F=25.320,P=0.000); 2組間周徑總體有差別(F=5.530,P=0.024),進一步比較顯示術后第6天治療組周徑小于對照組(F=175.303,P=0.000); 治療方法與時間因素之間存在交互作用(F=14.214,P=0.000)。小腿周徑:不同時間點周徑不全相同(F=67.520,P=0.000); 2組間周徑總體有差別(F=5.348,P=0.026),進一步比較顯示術后第2天、第6天、第10天治療組周徑小于對照組(F=13.960,P=0.001; F=42.183,P=0.000; F=7.678,P=0.009); 治療方法與時間因素之間存在交互作用(F=22.428,P=0.000)。②凝血指標。2組患者術后第2天凝血酶原時間及活化部分凝血活酶時間比較,差異無統(tǒng)計學意義(t=1.480,P=0.147; t=0.821,P=0.417); 治療組術后第14天與術后第2天凝血酶原時間及活化部分凝血活酶時間差值均大于對照組(t=2.117,P=0.041; t=2.104,P=0.042)。③血小板計數(shù)。不同時點血小板計數(shù)不全相同(F=67.155,P=0.000); 2組間血小板計數(shù)未見不同(F=0.716,P=0.403); 治療方法與時間因素之間不存在交互效應(F=0.318,P=0.591)。④切口引流量。術后治療組切口引流量小于對照組(t=1.520,P=0.137)。⑤血腫瘀斑發(fā)生情況。術后2組患者血腫、瘀斑發(fā)生情況比較,差異無統(tǒng)計學意義(P=0.244; χ2=2.667,P=0.102)。⑥深靜脈血栓發(fā)生情況。治療期間僅對照組2例發(fā)生深靜脈血栓,2組患者深靜脈血栓發(fā)生情況比較,差異無統(tǒng)計學意義(P=0.244)。結論:桃紅四妙湯結合低分子肝素鈣能明顯延長凝血酶原時間及活化部分凝血活酶時間,明顯減輕全膝關節(jié)置換術后患肢腫脹,減少術后出血,有效防治全膝關節(jié)置換術后深靜脈血栓形成,并且具有較高的安全性。
Abstract:
Objective:To explore the clinical curative effect and safety of TAOHONG SIMIAO DECOCTION combined with low molecular weight heparin calcium(LMWHC)in the preventive treatment of deep vein thrombosis(DVT)after total knee arthroplasty(TKA).Methods:Forty patients met the requirements were randomly divided into treatment group and control group,20 cases in each group.Patients in the treatment group were administrated with TAOHONG SIMIAO DECOCTION combined with LMWHC,while the others in the control group were administrated with LMWHC only.The swelling situations of the affected limbs,coagulation indexes,platelet count,incision drainage,hematoncus ecchymosis and DVT occurrences of the patients in the 2 groups were measured after TKA.Results:①The swelling situations of the affected limbs:On the aspect of thigh circumference:not all of the circumferences were same at the different time points(F=25.320,P=0.000); there was difference in circumference between the 2 groups totally(F=5.530,P=0.024),the circumference of treatment group was less than that of control group at the 6th day after TKA through the further comparison(F=175.303,P=0.000); there was an interaction between treatment method and time factor(F=14.214,P=0.000).On the aspect of calf circumference:not all of the circumferences were same at the different time points(F=67.520,P=0.000); there was difference in circumference between the 2 groups totally(F=5.348,P=0.026),the circumference of treatment group was less than that of control group at the 2nd,6th,10th day after TKA through the further comparison(F=13.960,P=0.001; F=42.183,P=0.000; F=7.678,P=0.009); there was an interaction between treatment method and time factor(F=22.428,P=0.000).②Coagulation indexes:There was no statistical difference in prothrombin time(PT)and activated partial thromboplastin time(APTT)between the 2 groups at the 2nd day after TKA(t=1.480,P=0.147; t=0.821,P=0.417); The difference in PT and APTT between the 14th postoperative day value and the 2nd postoperative day value of the treatment group were all larger than those of the control group(t=2.117,P=0.041; t=2.104,P=0.042).③Platelet count:not all of the platelet counts were same at the different time points(F=67.155,P=0.000); there was no difference in platelet count between the 2 groups(F=0.716,P=0.403); there was not an interaction between treatment method and time factor(F=0.318,P=0.591).④Incision drainage of treatment group was less than that of the control group after TKA(t=1.520,P=0.137).⑤There was no statistical difference in incidence of hematoncus and ecchymosis between the 2 groups(P=0.244; χ2=2.667,P=0.102).⑥D(zhuǎn)VT occurrences:Only 2 cases with DVT were found in the control group during the treatment period; there was no statistical difference in incidence of DVT between the 2 groups(P=0.244).Conclusion:The therapy of TAOHONG SIMIAO DECOCTION combined with LMWHC of higher safety can effectively prevent DVT through obviously extension of PT and APTT,obviously relieving of the affected limb swelling situations after TKA and reduction of postoperative bleeding.

參考文獻/References:

[1] Canale ST.坎貝爾骨科手術學[M].盧世壁,譯.9版.濟南:山東科學技術出版社,2000:266.
[2] 呂厚山,徐斌.人工關節(jié)置換術后下肢深靜脈血栓形成[J].中華骨科雜志,1999,19(1):155-160.
[3] 池明宇.中西醫(yī)結合血栓病學[M].北京:人民衛(wèi)生出版社,2004:443-444.
[4] 劉北南.傷科術后湯改善骨科術后高凝狀態(tài)及防治深靜脈血栓形成的臨床療效研究[D].山東:山東中醫(yī)藥大學,2001.
[5] 路世勇,李光磊,李福東.人工膝關節(jié)置換術后深靜脈血預防及治療[J].中國矯形外科雜志,2008,16(7):553-554.
[6] 曲洪雪,劉云鵬.骨科深靜脈血栓形成危險因素及發(fā)病機制的研究進展[J].中國矯形外科雜志,2009,17(2):110-112.
[7] 劉迅,童培建,章建華.活血通脈湯防治全膝關節(jié)置換術后深靜脈血栓33例[J].浙江中醫(yī)藥大學學報,2006,30(5):495-496.
[8] 陳靈敏,周海星.骨折患者手術前凝血功能檢測臨床意義[J].治療與檢驗醫(yī)學,2009,27(1):86.
[9] 王月梅,呂占清,陸彩云.凝血常規(guī)檢測在腦血管疾病抗血栓和溶血栓治療中的應用及評價[J].吉林醫(yī)學,2008,29(15):1268-1269.
[10] 莫霄云,錢海凌,李麗.活血化瘀利水中藥復方對老齡大鼠自由基和血液流變學的影響[J].遼寧中醫(yī)雜志,2004,31(5):436-437.

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備注/Memo

備注/Memo:
基金項目:廣東省中醫(yī)藥局建設中醫(yī)藥強省科研資助基金(粵中醫(yī)藥局2009036)
更新日期/Last Update: 2012-01-20