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[1]劉偉,顏純淳,于功昌,等.寒濕痹痛方外敷聯(lián)合本體感覺神經(jīng)肌肉促進(jìn)技術(shù)治療老年膝骨關(guān)節(jié)炎寒濕痹阻證的臨床研究[J].中醫(yī)正骨,2025,37(04):41-49,54.
 LIU Wei,YAN Chunchun,YU Gongchang,et al.External application of Hanshi Bitong Fang(寒濕痹痛方)combined with proprioceptive neuromuscular facilitation for treatment of knee osteoarthritis with cold-dampness stagnation syndrome in the aged:a clinical study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2025,37(04):41-49,54.
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寒濕痹痛方外敷聯(lián)合本體感覺神經(jīng)肌肉促進(jìn)技術(shù)治療老年膝骨關(guān)節(jié)炎寒濕痹阻證的臨床研究()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第37卷
期數(shù):
2025年04期
頁碼:
41-49,54
欄目:
臨床研究
出版日期:
2025-04-20

文章信息/Info

Title:
External application of Hanshi Bitong Fang(寒濕痹痛方)combined with proprioceptive neuromuscular facilitation for treatment of knee osteoarthritis with cold-dampness stagnation syndrome in the aged:a clinical study
作者:
劉偉1顏純淳1于功昌1楊苓2翟勁草3夏銳3馬曉雪3師彬1孫晉海2
1.山東第一醫(yī)科大學(xué)附屬頸肩腰腿痛醫(yī)院,山東 濟(jì)南 250062; 2.山東大學(xué)體育學(xué)院,山東 濟(jì)南 250061; 3.曲阜師范大學(xué)體育科學(xué)學(xué)院,山東 濟(jì)寧 273100
Author(s):
LIU Wei1YAN Chunchun1YU Gongchang1YANG Ling2ZHAI Jincao3XIA Rui3MA Xiaoxue3SHI Bin1SUN Jinhai2
1.Neck-Shoulder and Lumbocrural Pain Hospital Affiliated to Shandong First Medical University,Jinan 250062,Shandong,China 2.School of Physical Education,Shandong University,Jinan 250061,Shandong,China 3.School of Physical Education and Sports Science,Qufu Normal University,Jining 273100,Shandong,China
關(guān)鍵詞:
骨關(guān)節(jié)炎 寒濕痹阻證 敷貼療法 寒濕痹痛方 本體感覺 神經(jīng)肌肉促進(jìn)技術(shù) 老年人 隨機(jī)對(duì)照試驗(yàn)專題
Keywords:
osteoarthritisknee cold dampness stagnation syndrome plastering therapy Hanshi Bitong Fang proprioception neuromuscular facilitation technique aged randomized controlled trials as topic
摘要:
目的:觀察寒濕痹痛方外敷聯(lián)合本體感覺神經(jīng)肌肉促進(jìn)技術(shù)(proprioceptive neuromuscular facilitation,PNF)治療老年膝骨關(guān)節(jié)炎(knee osteoarthritis,KOA)寒濕痹阻證的臨床療效和安全性。方法:將符合要求的78例老年KOA寒濕痹阻證患者隨機(jī)分為2組,每組39例,分別采用寒濕痹痛方外敷聯(lián)合PNF治療(聯(lián)合PNF組)和單純PNF治療(PNF組)。分別于治療前與治療結(jié)束后,記錄并比較2組患者的西安大略和麥克馬斯特大學(xué)骨關(guān)節(jié)炎指數(shù)(Western Ontario and McMaster Universities osteoarthritis index,WOMAC)疼痛、僵硬和關(guān)節(jié)功能評(píng)分,膝關(guān)節(jié)屈曲與伸展峰值力矩,膝關(guān)節(jié)屈曲角度及下樓梯步態(tài)參數(shù)。觀察并發(fā)癥發(fā)生情況。結(jié)果:①WOMAC評(píng)分。治療結(jié)束后,2組患者WOMAC疼痛評(píng)分、僵硬評(píng)分及關(guān)節(jié)功能評(píng)分均低于治療前(疼痛評(píng)分:t=16.400,P=0.000; t=11.273,P=0.000; 僵硬評(píng)分:t=9.159,P=0.000; t=4.117,P=0.000; 關(guān)節(jié)功能評(píng)分:t=10.076,P=0.000; t=7.392,P=0.000),聯(lián)合PNF組患者WOMAC疼痛評(píng)分、僵硬評(píng)分及關(guān)節(jié)功能評(píng)分均低于PNF組(t=17.577,P=0.000; t=8.354,P=0.000; t=5.753,P=0.000)。②膝關(guān)節(jié)屈曲與伸展峰值力矩。治療結(jié)束后,2組患者膝關(guān)節(jié)屈曲峰值力矩與治療前的差異均無統(tǒng)計(jì)學(xué)意義(t=1.435,P=0.156; t=0.769,P=0.445),2組患者膝關(guān)節(jié)屈曲峰值力矩的差異無統(tǒng)計(jì)學(xué)意義(t=1.229,P=0.224),2組患者膝關(guān)節(jié)伸展峰值力矩均大于治療前(t=7.317,P=0.000; t=3.286,P=0.002),聯(lián)合PNF組患者膝關(guān)節(jié)伸展峰值力矩大于PNF組(t=2.695,P=0.009)。③膝關(guān)節(jié)屈曲角度。治療結(jié)束后,2組患者膝關(guān)節(jié)屈曲角度均大于治療前(t=4.655,P=0.000; t=4.870,P=0.000),2組患者膝關(guān)節(jié)屈曲角度的差異無統(tǒng)計(jì)學(xué)意義(t=1.025,P=0.309)。④下樓梯步態(tài)參數(shù)。治療結(jié)束后,聯(lián)合PNF組患者膝關(guān)節(jié)內(nèi)收峰值力矩小于治療前(t=31.379,P=0.000),PNF組患者膝關(guān)節(jié)內(nèi)收峰值力矩與治療前的差異無統(tǒng)計(jì)學(xué)意義(t=1.493,P=0.140),聯(lián)合PNF組患者膝關(guān)節(jié)內(nèi)收峰值力矩小于PNF組(t=20.033,P=0.000)。治療結(jié)束后,2組患者內(nèi)外和前后方向動(dòng)態(tài)穩(wěn)度值小于治療前(內(nèi)外方向:t=4.994,P=0.000; t=2.402,P=0.019; 前后方向:t=5.700,P=0.000; t=2.101,P=0.040),聯(lián)合PNF組患者內(nèi)外和前后方向動(dòng)態(tài)穩(wěn)度值小于PNF組(t=2.933,P=0.005; t=2.499,P=0.015)。⑤安全性。2組患者均未發(fā)生膝關(guān)節(jié)腫脹、感染、局部皮疹或瘀斑等并發(fā)癥。結(jié)論:寒濕痹痛方外敷聯(lián)合PNF治療KOA寒濕痹阻證,可有效緩解膝關(guān)節(jié)疼痛、僵硬癥狀,增強(qiáng)伸膝肌力,促進(jìn)膝關(guān)節(jié)功能恢復(fù),提高下樓梯時(shí)的步態(tài)穩(wěn)定性,療效優(yōu)于單純采用PNF治療,但二者在膝關(guān)節(jié)屈曲角度改善及安全性方面相當(dāng)。
Abstract:
Objective:To observe the clinical outcomes and safety of external application of Hanshi Bitong Fang(寒濕痹痛方,HSBTF)combined with proprioceptive neuromuscular facilitation(PNF)in treatment of knee osteoarthritis(KOA)with cold-dampness stagnation syndrome in the aged.Methods:Seventy-eight eligible aged KOA patients with cold-dampness stagnation syndrome were enrolled in the study and were randomized into 2 groups,39 ones in each group,and they were treated with external application of HSBTF combined with PNF(combination therapy group)and PNF alone(PNF group),respectively.The Western Ontario and McMaster Universities osteoarthritis index(WOMAC)scores(including pain score,stiffness score,and joint function score),peak torque for knee flexion/extension,knee flexion angle,and down stair gait biomechanical parameters were recorded and compared between the 2 groups before the treatment and after the end of the treatment,respectively,and the complications were observed.Results:①The WOMAC scores.The pain,stiffness,and joint function scores decreased after the end of the treatment compared to pre-treatment in the 2 groups(pain score:t=16.400,P=0.000; t=11.273,P=0.000; stiffness score:t=9.159,P=0.000; t=4.117,P=0.000; joint function score:t=10.076,P=0.000; t=7.392,P=0.000),and the scores were lower in combination therapy group compared to PNF group(t=17.577,P=0.000; t=8.354,P=0.000; t=5.753,P=0.000).②The peak torque for knee flexion/extension.No significant difference was observed in the peak torque for knee flexion between post-treatment and pre-treatment in the 2 groups(t=1.435,P=0.156; t=0.769,P=0.445)and between the 2 groups after the end of the treatment(t=1.229,P=0.224).The peak torque for knee extension increased after the end of the treatment compared to pre-treatment in the 2 groups(t=7.317,P=0.000; t=3.286,P=0.002),with more improvement in combination therapy group(t=2.695,P=0.009).③The knee flexion angle.The knee flexion angle increased after the end of the treatment compared to pre-treatment in the 2 groups(t=4.655,P=0.000; t=4.870,P=0.000),with no significant difference between the 2 groups(t=1.025,P=0.309).④The down stair gait biomechanical parameters.The peak torque for knee adduction shortened after the end of the treatment compared to pre-treatment in the combination therapy group(t=31.379,P=0.000),while,no significant difference was observed in PNF group(t=1.493,P=0.140).The peak torque for knee adduction was smaller in combination therapy group compared to PNF group(t=20.033,P=0.000).The dynamic stability values in the medial-lateral and anterior-posterior directions decreased after the end of the treatment compared to pre-treatment in the 2 groups(medial-lateral direction:t=4.994,P=0.000; t=2.402,P=0.019; anterior-posterior direction:t=5.700,P=0.000; t=2.101,P=0.040),with more decreasement in combination therapy group(t=2.933,P=0.005; t=2.499,P=0.015).⑤Safety.No patients experienced complications such as knee swelling,infection,local rash or ecchymosis in the 2 groups.Conclusion:External application of HSBTF combined with PNF can effectively alleviate the knee pain and stiffness symptoms,enhance knee extension muscle strength,promote knee function recovery,and improve down stair gait stability in treatment of KOA with cold-dampness stagnation syndrome in the aged,and its clinical outcome outperforms that of PNF alone,while,both are comparable in the knee flexion angle improvement and safety.

參考文獻(xiàn)/References:

[1] TANG X,WANG S,ZHAN S,et al.The prevalence of symptomatic knee osteoarthritis in China:results from the china health and retirement longitudinal study[J].Arthritis Rheumatol,2016,68(3):648-653.
[2] F?RMETZ J,SASS J,FERREIRA T,et al.Three-dimensional assessment of lower limb alignment:accuracy and reliability[J].Knee,2019,26(1):185-193.
[3] 黃銘汝,陳俊,陳世益,等.膝關(guān)節(jié)骨性關(guān)節(jié)炎運(yùn)動(dòng)療法研究進(jìn)展[J].中國運(yùn)動(dòng)醫(yī)學(xué)雜志,2022,41(4):320-329.
[4] 劉偉,于功昌,王從安,等.基于生物力學(xué)的膝骨關(guān)節(jié)炎運(yùn)動(dòng)療法與療效評(píng)價(jià)的研究進(jìn)展[J].中醫(yī)正骨,2023,35(2):46-50.
[5] 李輝萍,宋濤,鄧景貴,等.本體感覺神經(jīng)肌肉促進(jìn)技術(shù)對(duì)膝骨關(guān)節(jié)炎患者本體感覺及平衡能力的影響[J].中華物理醫(yī)學(xué)與康復(fù)雜志,2017,39(6):456-459.
[6] FRANSEN M,MCCONNELL S,HARMER A R,et al.Exercise for osteoarthritis of the knee:a cochrane systematic review[J].Br J Sports Med,2015,49(24):1554-1557.
[7] 王虎,陳順喜,陳益丹.溫針灸配合中藥外敷治療膝關(guān)節(jié)骨性關(guān)節(jié)炎對(duì)炎癥反應(yīng)及膝關(guān)節(jié)功能的影響[J].中華中醫(yī)藥學(xué)刊,2022,40(7):63-66.
[8] 鄭安平,鄭曉紅.經(jīng)典名方桂枝芍藥知母湯沿革演變與方證信息分析[J].中國實(shí)驗(yàn)方劑學(xué)雜志,2023,29(17):174-184.
[9] HOCHBERG M C,ALTMAN R D,BRANDT K D,et al.Guidelines for the medical management of osteoarthritis.Part Ⅱ.Osteoarthritis of the knee.American College of Rheumatology[J].Arthritis Rheum,1995,38(11):1541-1546.
[10] 中國中醫(yī)藥研究促進(jìn)會(huì)骨傷科分會(huì).膝骨關(guān)節(jié)炎中醫(yī)診療指南(2020年版)[J].中醫(yī)正骨,2020,32(10):1-14.
[11] 中華醫(yī)學(xué)會(huì)骨科學(xué)分會(huì)關(guān)節(jié)外科學(xué)組.骨關(guān)節(jié)炎診療指南(2018年版)[J].中華骨科雜志,2018,38(12):705-715.
[12] SHEN P,LI L,SONG Q,et al.Proprioceptive neuromuscular facilitation improves symptoms among older adults with knee osteoarthritis during stair ascending:a randomized controlled trial[J].Am J Phys Med Rehabil,2022,101(8):753-760.
[13] SONG Q,SHEN P,MAO M,et al.Proprioceptive neuromuscular facilitation improves pain and descending mechanics among elderly with knee osteoarthritis[J].Scand J Med Sci Sports,2020,30(9):1655-1663.
[14] 紀(jì)樹榮.運(yùn)動(dòng)療法技術(shù)學(xué)[M].2版.北京:華夏出版社,2011.
[15] 陳蔚,郭燕梅,李曉英,等.西安大略和麥克馬斯特大學(xué)骨關(guān)節(jié)炎指數(shù)的重測(cè)信度[J].中國康復(fù)理論與實(shí)踐,2010,16(1):23-24.
[16] BR?GIDO-FERN?NDEZ I,GARC?A-MURO SAN JOS? F,CHARNECO-SALGUERO G,et al.Knee isokinetic profiles and reference values of professional female soccer players[J].Sports(Basel),2022,10(12):204.
[17] 張琦,梁媛,張冉,等.運(yùn)動(dòng)學(xué)對(duì)線技術(shù)對(duì)全膝關(guān)節(jié)置換術(shù)后關(guān)節(jié)活動(dòng)度的效果[J].中國康復(fù)理論與實(shí)踐,2022,28(7):764-769.
[18] 郝鑫,于瀅,喬虎軍.膝關(guān)節(jié)炎的病因診斷及運(yùn)動(dòng)療法[J].當(dāng)代體育科技,2021,11(9):23-25.
[19] 張帥攀,朱清廣,孔令軍,等.膝痹的“筋骨力失衡”與現(xiàn)代生物力學(xué)的相關(guān)性探討[J].時(shí)珍國醫(yī)國藥,2021,32(6):1425-1428.
[20] 董亞煒,李述文,賈雁,等.《中國骨關(guān)節(jié)炎診療指南(2021版)》中醫(yī)藥相關(guān)內(nèi)容解讀[J].世界中醫(yī)藥,2023,18(16):2377-2381.
[21] 丁天送.基于“筋骨同治”理論DTT-HTO保膝治療對(duì)髕股關(guān)節(jié)影響的臨床研究[D].北京:北京中醫(yī)藥大學(xué),2023.
[22] WANG S,CAO M,XU S,et al.Luteolin alters macrophage polarization to inhibit inflammation[J].Inflammation,2020,43(1):95-108.
[23] HUNT M A,KEEFE F J,BRYANT C,et al.A physiotherapist-delivered,combined exercise and pain coping skills training intervention for individuals with knee osteoarthritis:a pilot study[J].Knee,2013,20(2):106-112.
[24] 章曉云,李華南,陳鋒,等.網(wǎng)絡(luò)藥理學(xué)結(jié)合分子對(duì)接技術(shù)揭示桂枝芍藥知母湯治療痛風(fēng)性關(guān)節(jié)炎的潛在分子機(jī)制[J].中國組織工程研究,2022,26(2):245-252.
[25] PACHRUDDIN I,RUSLY H,NASARUDDIN F.Effect of proprioceptive neuromuscular facilitation(PNF)on standing balance control among post stroke patients[J].J Phys Conf Ser,2020,1529:032033.
[26] CHO M,GONG W.The effects of dynamic exercise using the proprioceptive neuromuscular facilitation pattern on posture in healthy adults[J].J Phys Ther Sc,2017,29(6):1070-1073.
[27] 王靜文,劉偉,高博,等.中藥熱敷結(jié)合運(yùn)動(dòng)療法對(duì)老年膝骨關(guān)節(jié)炎患者跨越障礙物時(shí)疼痛、關(guān)節(jié)力矩和動(dòng)態(tài)穩(wěn)度的作用[J].中國老年學(xué)雜志,2024,44(5):1091-1096.
[28] HINDLE K B,WHITCOMB T J,BRIGGS W O,et al.Proprioceptive neuromuscular facilitation(PNF):its mechanisms and effects on range of motion and muscular function[J].J Hum Kinet,2012,31:105-113.
[29] LI Y,LUO R,LUO S,et al.Influencing factors analysis of asymmetry in knee adduction moment among patients with unilateral knee osteoarthritis[J].BMC Musculoskelet Disord,2024,25(1):832.
[30] 楊珺,盛揚(yáng),趙玥,等.等速肌力訓(xùn)練聯(lián)合肌內(nèi)效貼對(duì)骨關(guān)節(jié)炎患者膝關(guān)節(jié)穩(wěn)定性的影響[J].風(fēng)濕病與關(guān)節(jié)炎,2021,10(3):20-23.
[31] 沈培鑫,羅心,車欣恒,等.本體感覺神經(jīng)肌肉促進(jìn)技術(shù)對(duì)老年膝骨關(guān)節(jié)炎患者步行時(shí)關(guān)節(jié)負(fù)荷效果的隨機(jī)對(duì)照試驗(yàn)[J].中國康復(fù)理論與實(shí)踐,2024,30(7):854-860.
[32] CHANG A H,ALMAGOR O,LEE J J,et al.The natural history of knee osteoarthritis pain experience and risk profiles[J].J Pain,2023,24(12):2175-2185.
[33] UNVER B, ERTEKIN Ö,KARATOSUN V.Pain,fear of falling and stair climbing ability in patients with knee osteoarthritis before and after knee replacement:6 month follow-up study[J].J Back Musculoskelet Rehabil,2014,27(1):77-84.
[34] DUFFELL L D,SOUTHGATE D F,GULATI V,et al.Ba-lance and gait adaptations in patients with early knee osteoarthritis[J].Gait Posture,2014,39(4):1057-1061.

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[1]樊慶陽,任凱晶.定制3D打印切模輔助全膝關(guān)節(jié)置換術(shù)治療 膝骨關(guān)節(jié)炎合并股骨干骨折畸形愈合[J].中醫(yī)正骨,2015,27(11):37.
[2]劉曉雅,孫永強(qiáng),劉國杰.主動(dòng)快速康復(fù)鍛煉對(duì)全膝關(guān)節(jié)置換術(shù)后關(guān)節(jié)活動(dòng)度的影響[J].中醫(yī)正骨,2015,27(09):73.
[3]鄭春松,葉蕻芝,李西海,等.透骨消痛膠囊中補(bǔ)腎柔肝藥和活血祛風(fēng)藥治療 骨關(guān)節(jié)炎作用方式的計(jì)算機(jī)模擬比較[J].中醫(yī)正骨,2015,27(07):6.
 ZHENG Chunsong,YE Hongzhi,LI Xihai,et al.Comparison of the mode of action of Bushen Rougan(補(bǔ)腎柔肝)drugs versus Huoxue Qufeng(活血祛風(fēng))drugs contained in Tougu Xiaotong Jiaonang(透骨消痛膠囊)for the treatment of osteoarthritis:A computer simulation study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(04):6.
[4]宋兵華,孫俊英,倪增良,等.全膝關(guān)節(jié)置換術(shù)前CT測(cè)量股骨后髁角的臨床意義[J].中醫(yī)正骨,2015,27(07):38.
[5]鄭春松,葉蕻芝,李西海,等.獨(dú)活寄生湯含藥血清對(duì)白細(xì)胞介素1β誘導(dǎo)的 退變關(guān)節(jié)軟骨細(xì)胞中基質(zhì)金屬蛋白酶 和環(huán)氧化酶2表達(dá)的影響[J].中醫(yī)正骨,2015,27(12):1.
 ZHENG Chunsong,YE Hongzhi,LI Xihai,et al.Impact of Duhuo Jisheng Tang(獨(dú)活寄生湯)medicated serum on expression of matrix metalloproteinase and cyclooxygenase 2 in degenerative articular chondrocytes induced by interleukin-1 beta[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(04):1.
[6]王金良,孫京濤,李玲,等.骨水泥聯(lián)合螺釘修復(fù)全膝關(guān)節(jié)置換術(shù)中 脛骨平臺(tái)內(nèi)側(cè)骨缺損[J].中醫(yī)正骨,2015,27(12):55.
[7]馮榮,王平,李炳奇,等.鈹針刺絡(luò)拔罐結(jié)合中藥口服治療膝骨關(guān)節(jié)炎合并 原發(fā)性血小板增多癥1例[J].中醫(yī)正骨,2015,27(12):73.
[8]蔡云仙.圍手術(shù)期耳穴按壓聯(lián)合平衡針療法 在全膝關(guān)節(jié)置換術(shù)后鎮(zhèn)痛中的應(yīng)用[J].中醫(yī)正骨,2015,27(06):41.
[9]張榮,王健.人工全膝關(guān)節(jié)置換術(shù)的圍手術(shù)期心理護(hù)理[J].中醫(yī)正骨,2015,27(05):77.
[10]喻長(zhǎng)純,楊明路,王戰(zhàn)朝.不同手術(shù)方式治療脛骨平臺(tái)骨折畸形愈合的體會(huì)[J].中醫(yī)正骨,2015,27(03):37.
[11]孟維娜,明立功,王新德,等.關(guān)節(jié)鏡下清理聯(lián)合腓骨近1/3段截骨治療膝骨關(guān)節(jié)炎[J].中醫(yī)正骨,2015,27(11):40.
[12]明立功,孟維娜,王新德,等.腓骨近端截骨治療內(nèi)側(cè)間室膝骨關(guān)節(jié)炎的近期療效觀察[J].中醫(yī)正骨,2015,27(10):25.
[13]張杰,王人彥,張玉柱.膝骨關(guān)節(jié)炎的治療進(jìn)展[J].中醫(yī)正骨,2015,27(10):68.
[14]梁朝,蔡靜怡,閆立,等.針刀療法改善膝骨關(guān)節(jié)炎早期疼痛癥狀的療效評(píng)價(jià)[J].中醫(yī)正骨,2015,27(09):9.
 LIANG Zhao,CAI Jingyi,YAN Li,et al.Evaluation of the curative effect of needle-knife therapy for relieving knee pain in patients with early knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(04):9.
[15]王建武,黨建軍,李強(qiáng),等.四聯(lián)療法治療膝骨關(guān)節(jié)炎[J].中醫(yī)正骨,2015,27(08):44.
[16]劉紅娟,郭會(huì)利,郭樹農(nóng).云克聯(lián)合中藥治療膝骨關(guān)節(jié)炎的護(hù)理[J].中醫(yī)正骨,2015,27(08):75.
[17]陳衛(wèi)衡.探索建立系統(tǒng)的膝骨關(guān)節(jié)炎中醫(yī)臨床科研范式 和理論體系[J].中醫(yī)正骨,2015,27(07):1.
[18]帥波,沈霖,楊艷萍,等.加味青娥丸治療膝骨關(guān)節(jié)炎的作用機(jī)制研究[J].中醫(yī)正骨,2015,27(07):15.
 SHUAI Bo,SHEN Lin,YANG Yanping,et al.Study on the mechanism of action of Jiawei Qing'e Wan(加味青娥丸)for the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(04):15.
[19]梅其杰,袁長(zhǎng)深,段戡,等.壯藥骨痹方燙熨聯(lián)合運(yùn)動(dòng)療法治療膝骨關(guān)節(jié)炎的臨床研究[J].中醫(yī)正骨,2015,27(07):27.
 MEI Qijie,YUAN Changshen,DUAN Kan,et al.Clinical study of the curative effect of hot compressing and rubbing with packet of Gubi Fang(骨痹方)combined with exercise therapy in the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(04):27.
[20]王丹輝,張燕,劉麗娟,等.重組人Ⅱ型腫瘤壞死因子受體-抗體融合蛋白 關(guān)節(jié)腔注射聯(lián)合中藥薰洗治療膝骨關(guān)節(jié)炎的臨床研究[J].中醫(yī)正骨,2015,27(07):31.
 WANG Danhui,ZHANG Yan,LIU Lijuan,et al.Clinical study on intra-articular injection of TypeⅡrecombinant human tumor necrosis factor receptor-Fc fusion protein combined with Chinese herbal steaming and washing therapy for treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(04):31.

備注/Memo

備注/Memo:
基金項(xiàng)目:國家自然科學(xué)基金項(xiàng)目(82374615); 山東省中醫(yī)藥科技項(xiàng)目(2021M149,M-2022253)
通訊作者:孫晉海 E-mail:[email protected]
更新日期/Last Update: 1900-01-01