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[1]易林,熱米拉·艾買(mǎi)提,張文豪,等.中藥基于核因子-κB信號(hào)通路治療骨關(guān)節(jié)炎作用機(jī)制的研究進(jìn)展[J].中醫(yī)正骨,2023,35(09):49-52.
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中藥基于核因子-κB信號(hào)通路治療骨關(guān)節(jié)炎作用機(jī)制的研究進(jìn)展()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期數(shù):
2023年09期
頁(yè)碼:
49-52
欄目:
綜述
出版日期:
2023-09-20

文章信息/Info

作者:
易林熱米拉·艾買(mǎi)提張文豪向文遠(yuǎn)鄧迎杰方銳
新疆醫(yī)科大學(xué)附屬中醫(yī)醫(yī)院,新疆 烏魯木齊 830000
關(guān)鍵詞:
骨關(guān)節(jié)炎 中藥 NF-κB 信號(hào)傳導(dǎo) 綜述
摘要:
骨關(guān)節(jié)炎(osteoarthritis,OA)是一種臨床上常見(jiàn)的慢性退行性關(guān)節(jié)疾病。核因子-κB(nuclear factor-κB,NF-κB)信號(hào)通路參與機(jī)體的免疫應(yīng)答、炎癥反應(yīng)、細(xì)胞分化、細(xì)胞凋亡等多種生物過(guò)程,與OA的發(fā)生發(fā)展關(guān)系密切。中藥在改善OA癥狀方面療效顯著,而中藥治療OA的作用機(jī)制與抑制NF-κB信號(hào)通路的異常激活關(guān)系密切。本文概述了NF-κB信號(hào)通路,探討了NF-κB信號(hào)通路與OA的關(guān)系,對(duì)中藥基于NF-κB信號(hào)通路治療OA作用機(jī)制的研究進(jìn)展進(jìn)行了綜述。

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備注/Memo

備注/Memo:
基金項(xiàng)目:新疆維吾爾自治區(qū)重點(diǎn)研發(fā)計(jì)劃項(xiàng)目(2021B03006-2); 新疆維吾爾自治區(qū)自然科學(xué)基金項(xiàng)目(2022D01C170,2022D01C171)
通訊作者:方銳 E-mail:[email protected]
更新日期/Last Update: 1900-01-01