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[1]張?jiān)?張玉良,羅程,等.經(jīng)皮椎體成形術(shù)與非手術(shù)療法治療骨質(zhì)疏松性椎體壓縮骨折療效比較的Meta分析[J].中醫(yī)正骨,2023,35(07):34-39,45.
　ZHANG Yuanbin,ZHANG Yuliang,LUO Cheng,et al.Clinical outcomes of percutaneous vertebroplasty versus non-operative therapies for treatment of osteoporotic vertebral compression fracture:a meta-analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2023,35(07):34-39,45.
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經(jīng)皮椎體成形術(shù)與非手術(shù)療法治療骨質(zhì)疏松性椎體壓縮骨折療效比較的Meta分析()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期數(shù):
2023年07期
頁碼:
34-39,45
欄目:
文獻(xiàn)研究
出版日期:
2023-07-20

文章信息/Info

Title:
Clinical outcomes of percutaneous vertebroplasty versus non-operative therapies for treatment of osteoporotic vertebral compression fracture:a meta-analysis
作者:
張玉良1; 羅程1; 趙瑛1; 施華萍1; 郎永2; 孫奇2
(1.杭州市富陽中醫(yī)骨傷醫(yī)院,浙江 杭州 311400; 2.張紹富中醫(yī)骨傷學(xué)術(shù)研究所,浙江 杭州 311400)
Author(s):
ZHANG Yuanbin1; ZHANG Yuliang1; LUO Cheng1; ZHAO Ying1; SHI Huaping1; LANG Yong2; SUN Qi2
1.Hangzhou Fuyang Hospital of Orthopedics of Traditional Chinese Medicine,Hangzhou 311400,Zhejiang,China 2.Academic Research Institute of TCM Orthopedics of ZHANG Shaofu,Hangzhou 311400,Zhejiang,China
關(guān)鍵詞:
骨質(zhì)疏松性骨折;  脊柱骨折;  椎體成形術(shù);  非手術(shù)療法;  專題Meta分析
Keywords:
osteoporotic fractures;  spinal fractures;  vertebroplasty;  nonoperative therapy;  meta-analysis as topic
摘要:
目的:系統(tǒng)評(píng)價(jià)經(jīng)皮椎體成形術(shù)(percutaneous vertebroplasty,PVP)和非手術(shù)療法治療骨質(zhì)疏松性椎體壓縮骨折(osteoporotic vertebral compression fracture,OVCF)的臨床療效。方法:應(yīng)用計(jì)算機(jī)檢索中國知網(wǎng)、萬方數(shù)據(jù)庫、維普網(wǎng)、PubMed、Embase、Cochrane Library、Medline中比較PVP和非手術(shù)療法治療OVCF臨床療效的隨機(jī)對(duì)照試驗(yàn),檢索時(shí)限均為建庫至2022年1月。同時(shí)通過人工檢索納入文獻(xiàn)的
Abstract:
Objective:To systematically review the clinical outcomes of percutaneous vertebroplasty(PVP)versus non-operative therapies in treatment of osteoporotic vertebral compression fracture(OVCF).Methods:All the randomized controlled trial(RCT)articles about the clinical outcomes of PVP(operation group)versus non-operative therapies(non-operation group)in treatment of OVCF included from database establishing to January 2022 were retrieved from the China National Knowledge Internet,Wanfang Database,Vip Database,PubMed,Embase,Cochrane Library and Medline through computer,meanwhile,the references of the included articles were manually retrieved for supplementing.The patients in operation group were treated with PVP,while the ones in non-operation group with non-operative therapies such as fixing and braking,physicotherapeutics and oral application of analgesics.The articles were screened and the information was extracted independently by two researchers according to the inclusion and exclusion criteria.The methodological quality of research in the articles was evaluated respectively independently by the same two researchers,and if any disagreement was found between them,discussion was conducted or another researcher was invited for making a final decision,and then a Meta-analysis was conducted by using RevMan5.3 software.Results:Eight RCT articles(748 patients)were included in the final analysis,380 patients in operation group and 368 ones in non-operation group.The results of Meta-analysis revealed that the posttreatment low back pain visual analogue scale(VAS)score and the posttreatment quality of life questionnaire of the European Foundation for Osteoporosis(QUALEFFO)score were lower in operation group compared to non-operation group(MD=-1.62,95%CI(-1.91,-1.32),P=0.000; MD=-5.62,95%CI(-8.94,-2.30),P=0.001).The results of subgroup analysis showed that the low back pain VAS scores were all lower in operation group compared to non-operation group within 1 month after the treatment,at 1-3 months after the treatment and over 3 months after the treatment respectively(MD=-1.78,95%CI(-2.63,-0.93),P=0.000; MD=-1.71,95%CI(-2.11,-1.31),P=0.000; MD=-1.29,95%CI(-1.69,-0.88),P=0.000).The QUALEFFO score was lower in operation group compared to non-operation group within 1 month after the treatment(MD=-6.25,95%CI(-11.69,-0.81),P=0.000),while,at 1-3 months after the treatment and over 3 months after the treatment,there was no statistical difference between the 2 groups(MD=-6.49,95%CI(-15.32,2.33),P=0.150; MD=-3.48,95%CI(-9.64,2.68),P=0.270).Publication bias was analyzed based on the posttreatment pain VAS scores,and the results of Egger's test showed that there was no publication bias in the included articles(within 1 month after the treatment:P=0.452; at 1-3 months after the treatment:P=0.633; over 3 months after the treatment:P=0.532).Conclusion:PVP is better than non-operative therapies in clinical outcomes in treatment of OVCF.

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中醫(yī)正骨2023年7月第35卷第7期 J Trad Chin Orthop Trauma,2023,Vol.35,No.7(總519)
(總520)中醫(yī)正骨2023年7月第35卷第7期 J Trad Chin Orthop Trauma,2023,Vol.35,No.7
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備注/Memo

備注/Memo:
基金項(xiàng)目:浙江省醫(yī)藥衛(wèi)生科技計(jì)劃項(xiàng)目(2020KY806) 通訊作者:張玉良 E-mail:[email protected]
更新日期/Last Update: 1900-01-01