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[1]許云騰,卓俊寬,張海鳳,等.基于生物節(jié)律與骨代謝關系的研究探討絕經后骨質疏松癥的防治策略[J].中醫(yī)正骨,2023,35(02):61-65.
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基于生物節(jié)律與骨代謝關系的研究探討絕經后骨質疏松癥的防治策略()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期數:
2023年02期
頁碼:
61-65
欄目:
學術探討
出版日期:
2023-02-20

文章信息/Info

作者:
許云騰1卓俊寬1張海鳳1陳鑫雨2韓一旦1張欣1段辛威1朱在師1嚴輝2王珊珊2王曉寧2李西海2
(1.福建中醫(yī)藥大學中西醫(yī)結合研究院,福建 福州 350122; 2.福建中醫(yī)藥大學中西醫(yī)結合學院,福建 福州 350122)
關鍵詞:
骨質疏松絕經后 生物節(jié)律 骨生成 骨質吸收
摘要:
絕經后骨質疏松癥是一種以骨吸收和骨形成耦聯失衡為基本發(fā)病機制的代謝性疾病。骨代謝受到生物節(jié)律的嚴格調控,包括激素分泌的節(jié)律性、骨細胞代謝的節(jié)律性及生物鐘基因的協調表達等。對骨代謝相關生物節(jié)律調控機制的深入研究,能夠闡明節(jié)律性骨重建的生理基礎和絕經后骨質疏松癥的部分發(fā)病機制,進而為探討絕經后骨質疏松癥的防治策略提供新思路。本文概述了生物節(jié)律與骨代謝的關系,對生物節(jié)律系統與骨代謝關系分子機制的研究進展進行了綜述,并基于生物節(jié)律與骨代謝的關系探討了絕經后骨質疏松癥的防治策略。

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(收稿日期:2022-07-14 本文編輯:呂寧)

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備注/Memo

備注/Memo:
基金項目:國家自然科學基金項目(82074461) 通訊作者:李西海 E-mail:[email protected]
更新日期/Last Update: 1900-01-01