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[1]鄢來軍,葛海雅,周斌,等.峽部裂性與退變性腰椎滑脫患者腰椎退變程度的影像學(xué)比較研究[J].中醫(yī)正骨,2023,35(02):15-21.
 YAN Laijun,GE Haiya,ZHOU Bin,et al.A comparative imaging study of the degree of lumbar vertebrae degeneration of isthmic spondylolisthesis versus degenerative spondylolisthesis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2023,35(02):15-21.
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峽部裂性與退變性腰椎滑脫患者腰椎退變程度的影像學(xué)比較研究()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期數(shù):
2023年02期
頁碼:
15-21
欄目:
臨床研究
出版日期:
2023-02-20

文章信息/Info

Title:
A comparative imaging study of the degree of lumbar vertebrae degeneration of isthmic spondylolisthesis versus degenerative spondylolisthesis
作者:
鄢來軍1葛海雅2周斌1袁宏杰1詹紅生2
(1.南通市中醫(yī)院,江蘇 南通 226000; 2.上海中醫(yī)藥大學(xué)附屬曙光醫(yī)院,上海 201203)
Author(s):
YAN Laijun1GE Haiya2ZHOU Bin1YUAN Hongjie1ZHAN Hongsheng2
1.Nantong Hospital of Traditional Chinese Medicine,Nantong 226000,Jiangsu,China 2.Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China
關(guān)鍵詞:
脊椎滑脫 腰椎 椎間盤退化 放射攝影術(shù) 磁共振成像
Keywords:
spondylolysis lumbar vertebrae intervertebral disc degeneration radiography magnetic resonance imaging
摘要:
目的:比較峽部裂性與退變性腰椎滑脫患者的腰椎退變程度。方法:回顧性分析2015年1月至2022年3月在南通市中醫(yī)院收治的170例腰椎滑脫患者的病例資料,其中峽部裂性滑脫85例(峽部裂組)、退變性滑脫85例(退變組)。在腰椎側(cè)位X線片上采用Meyerding分級標(biāo)準(zhǔn)評估腰椎滑脫程度; 在腰椎MRI上采用Pfirrmann分級標(biāo)準(zhǔn)評估椎間盤退變程度,采用Modic改變分級標(biāo)準(zhǔn)評估終板退變程度,采用Weishaupt分級標(biāo)準(zhǔn)評估關(guān)節(jié)突關(guān)節(jié)退變程度。比較2組患者的腰椎滑脫Meyerding分級、椎間盤Pfirrmann分級、終板Modic改變分級及關(guān)節(jié)突關(guān)節(jié)Weishaupt分級。結(jié)果:①腰椎滑脫Meyerding分級。峽部裂組腰椎滑脫MeyerdingⅠ度32例、Ⅱ度48例、Ⅲ度5例,退變組腰椎滑脫MeyerdingⅠ度59例、Ⅱ度26例; 峽部裂組腰椎滑脫程度較退變組更嚴(yán)重(Z=-4.323,P=0.000)。②椎間盤Pfirrmann分級。峽部裂組椎間盤PfirrmannⅢ級43例、Ⅳ級34例、Ⅴ級8例,退變組椎間盤PfirrmannⅢ級33例、Ⅳ級47例、Ⅴ級5例; 2組患者椎間盤退變程度比較,差異無統(tǒng)計學(xué)意義(Z=-1.121,P=0.262)。③終板Modic改變分級。峽部裂組終板Modic0級18例、Ⅰ級7例、Ⅱ級46例、Ⅲ級14例,退變組終板Modic0級27例、Ⅰ級6例、Ⅱ級47例、Ⅲ級5例; 峽部裂組終板退變程度較退變組更嚴(yán)重(Z=-2.051,P=0.040)。④關(guān)節(jié)突關(guān)節(jié)Weishaupt分級。峽部裂組關(guān)節(jié)突關(guān)節(jié)Weishaupt0級2例、Ⅰ級27例、Ⅱ級33例、Ⅲ級23例,退變組關(guān)節(jié)突關(guān)節(jié)WeishauptⅠ級25例、Ⅱ級30例、Ⅲ級30例; 2組患者關(guān)節(jié)突關(guān)節(jié)退變程度比較,差異無統(tǒng)計學(xué)意義(Z=-1.140,P=0.254)。結(jié)論:峽部裂性腰椎滑脫患者與退變性腰椎滑脫患者的椎間盤與關(guān)節(jié)突關(guān)節(jié)退變程度相似,但前者的腰椎滑脫和終板退變程度較后者更嚴(yán)重。
Abstract:
Objective:To compare the degree of lumbar vertebrae degeneration between patients with isthmic spondylolisthesis(IS)and patients with degenerative spondylolisthesis(DS).Methods:The medical data of 170 patients with spondylolisthesis admitted to Nantong Hospital of Traditional Chinese Medicine from January 2015 to March 2022 were retrospectively analyzed,including 85 cases with IS(IS group)and 85 cases with DS(DS group).The degree of lumbar spondylolisthesis was evaluated by using Meyerding classification criteria on lateral radiographs of lumbar vertebrae.The Pfirrmann grading scale was used to assess the degree of intervertebral disc degeneration on lumbar magnetic resonance imaging(MRI)images.The Modic changes classification method was employed to evaluate the degree of vertebral endplate degeneration.The degree of facet joint degeneration was assessed using the Weishaupt scale.Meyerding grading of lumbar spondylolisthesis,Pfirrmann grading of intervertebral disc,Modic change grading of vertebral endplate,and Weishaupt grading of facet joint were compared between the two groups.Results:①M(fèi)eyerding grading of lumbar spondylolisthesis.In the IS group,there were 32 cases of Meyerding gradeⅠ,48 cases of gradeⅡ,and 5 cases of gradeⅢ; while in the DS group,there were 59 cases of Meyerding gradeⅠand 26 cases of gradeⅡ.The spondylolisthesis was more severe in the IS group than in the DS group(Z=-4.323,P=0.000).②Pfirrmann grading of intervertebral disc.In the IS group,there were 43 cases of Pfirrmann gradeⅢ,34 cases of gradeⅣ,and 8 cases of gradeⅤ; and there were 33 cases of Pfirrmann gradeⅢ,47 cases of gradeⅣ,and 5 cases of gradeⅤin the DS group.There was no significant difference in the degree of intervertebral disc degeneration between the two groups(Z=-1.121,P=0.262).③Modic change grading of vertebral endplate.In the IS group,there were 18 cases of Modic type-0,7 cases of type-Ⅰ,46 cases of type-Ⅱ,and 14 cases of type-Ⅲ; while in the DS group,there were 27 cases of Modic type-0,6 cases of type-Ⅰ,47 cases of type-Ⅱ,and 5 cases of type-Ⅲ.The degeneration of vertebral endplate in the IS group was more severe than that in the DS group(Z=-2.051,P=0.040).④Weishaupt grading of facet joint.There were 2 cases of Weishaupt grade 0,27 cases of gradeⅠ,33 cases of gradeⅡ,and 23 cases of gradeⅢin the IS group,and 25 cases of Weishaupt gradeⅠ,30 cases of gradeⅡ,and 30 cases of gradeⅢin the DS group.There was no significant difference in the degree of facet joint degeneration between the two groups(Z=-1.140,P=0.254).Conclusion:IS is similar to DS in the degeneration degree of intervertebral disc and facet joint,but the degree of spondylolisthesis and vertebral endplate degeneration is more severe in IS patients than in DS patients.

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(收稿日期:2022-07-01 本文編輯:時紅磊)

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備注/Memo

備注/Memo:
基金項目:詹紅生2022年全國名老中醫(yī)藥專家傳承工作室建設(shè)項目(國中醫(yī)藥人教函〔2022〕75號); 上海市2020年度“科技創(chuàng)新行動計劃”醫(yī)學(xué)創(chuàng)新研究專項項目(20MC1920600); 上海市臨床重點專科建設(shè)項目(shslczdzk03901); 南通市衛(wèi)生和計劃生育委員會科研課題(QA2021025); 上海中醫(yī)藥大學(xué)附屬曙光醫(yī)院第二輪《促進(jìn)市級醫(yī)院臨床技能與臨床創(chuàng)新三年行動計劃》重大臨床研究項目(SHDC2020CR1051B) 通訊作者:詹紅生 E-mail:[email protected]
更新日期/Last Update: 1900-01-01