84年鼠女哪年财运最旺,857comvvv色九欧美激情|85PO_87国产精品欲av国产av资源

[1]王煜東,汪利合,孫明帥,等.不同藥物關(guān)節(jié)內(nèi)注射治療膝骨關(guān)節(jié)炎療效的網(wǎng)狀Meta分析[J].中醫(yī)正骨,2022,34(09):24-23.
　WANG Yudong,WANG Lihe,SUN Mingshuai,et al.Clinical efficacy of knee intra-articular injection of different drugs for treatment of knee osteoarthritis:a network meta-analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2022,34(09):24-23.
點擊復(fù)制

不同藥物關(guān)節(jié)內(nèi)注射治療膝骨關(guān)節(jié)炎療效的網(wǎng)狀Meta分析()
分享到：

《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第34卷
期數(shù):
2022年09期
頁碼:
24-23
欄目:
文獻(xiàn)研究
出版日期:
2022-09-20

文章信息/Info

Title:
Clinical efficacy of knee intra-articular injection of different drugs for treatment of knee osteoarthritis:a network meta-analysis
作者:
王煜東; 汪利合; 孫明帥; 李藝鳴; 高瑞永
(河南中醫(yī)藥大學(xué)第一附屬醫(yī)院,河南鄭州450000)
Author(s):
WANG Yudong; WANG Lihe; SUN Mingshuai; LI Yiming; GAO Ruiyong
The First Affiliated Hospital of Henan University of CM,Zhengzhou 450000,Henan,China
關(guān)鍵詞:
骨關(guān)節(jié)炎; 膝;  注射; 關(guān)節(jié)內(nèi);  網(wǎng)狀Meta分析
Keywords:
osteoarthritis; knee;  injections; intra-articular;  network meta-analysis
摘要:
目的:評價不同藥物關(guān)節(jié)內(nèi)注射治療膝骨關(guān)節(jié)炎(knee osteoarthritis,KOA)的療效。方法:應(yīng)用計算機(jī)檢索中國知網(wǎng)、萬方數(shù)據(jù)庫、維普網(wǎng)、PubMed、Cochrane Library,搜集關(guān)于關(guān)節(jié)內(nèi)注射治療KOA的隨機(jī)對照試驗文獻(xiàn),檢索時間范圍均為2016年1月至2021年1月。經(jīng)過文獻(xiàn)篩選、數(shù)據(jù)提取及偏倚風(fēng)險評價后,采用Stata14軟件繪制網(wǎng)狀關(guān)系圖和比較-校正漏斗圖,采用ADDIS1.16.6軟件對治療有效率、膝關(guān)節(jié)疼痛視覺模擬量表(visual analogue scale,VAS)評分、西安大略和麥克馬斯特大學(xué)骨關(guān)節(jié)炎指數(shù)(Western Ontario and McMaster Universities osteoarthritis index,WOMAC)評分進(jìn)行網(wǎng)狀Meta分析,并按照每個干預(yù)措施成為最佳干預(yù)措施的概率(Rank1概率)進(jìn)行療效排序。結(jié)果:共檢索到3123篇文獻(xiàn),經(jīng)過逐層篩選,最終納入40項隨機(jī)對照試驗,涉及糖皮質(zhì)激素(glucocorticoid,GC)、臭氧(ozone,O3)、玻璃酸鈉(sodium hyaluronate,SH)、富血小板血漿(platelet rich plasma,PRP)、間充質(zhì)干細(xì)胞(mesenchymal stem cell,MSC)、PRP+SH、O3+SH、SH+GC、酮咯酸氨丁三醇(ketorolac tromethamine,KT)+SH、MSC+PRP共10種關(guān)節(jié)內(nèi)注射藥物和藥物組合,以及作為安慰劑的生理鹽水(normal saline,NS)。在治療有效率方面,各種關(guān)節(jié)內(nèi)注射藥物的療效排序為PRP+SH(Rank1概率=0.38)>O3+SH(Rank1概率=0.34)>SH+GC(Rank1概率=0.18)>MSC+PRP(Rank1概率=0.05)>KT+SH(Rank1概率=0.03)>PRP(Rank1概率=0.02)>SH(Rank1概率=0.00)=O3(Rank1概率=0.00)=GC(Rank1概率=0.00); 在改善膝關(guān)節(jié)疼痛VAS評分方面,各種關(guān)節(jié)內(nèi)注射藥物的療效排序為PRP+SH(Rank1概率=0.43)>O3+SH(Rank1概率=0.25)>O3(Rank1概率=0.12)>KT+SH(Rank1概率=0.07)>MSC(Rank1概率=0.06)>MSC+PRP(Rank1概率=0.04)>SH+GC(Rank1概率=0.02)>GC(Rank1概率=0.01)>PRP(Rank1概率=0.00)=SH(Rank1概率=0.00); 在改善WOMAC評分方面,各種關(guān)節(jié)內(nèi)注射藥物的療效排序為PRP+SH(Rank1概率=0.42)>O3+SH(Rank1概率=0.20)>MSC+PRP(Rank1概率=0.18)>MSC(Rank1概率=0.12)>KT+SH(Rank1概率=0.04)>生理鹽水(Rank1概率=0.03)>PRP(Rank1概率=0.00)=SH(Rank1概率=0.00)=GC(Rank1概率=0.00)。結(jié)論:現(xiàn)有的證據(jù)表明,采用關(guān)節(jié)內(nèi)注射治療KOA時應(yīng)優(yōu)先選擇聯(lián)合用藥,其中SH聯(lián)合PRP或O3療效較好。
Abstract:
Objective:To evaluate the clinical efficacy of knee intra-articular injection of different drugs for treatment of knee osteoarthritis(KOA).Methods:All the randomized controlled trial(RCT)articles about knee intra-articular injection of different drugs for treatment of KOA included from January 2016 to January 2021 were retrieved from the China National Knowledge Internet,Wanfang Database,Vip Database,PubMed and Cochrane Library through computer.The articles were screened and the information was extracted according to the inclusion and exclusion criteria,and the bias risk of the research in the articles was evaluated using Cochrane bias risk assessment tools independently by two researchers.If any disagreement was found between them,they would ask for another researcher for making a final decision.The network relationship diagrams and comparison-correction funnel plots were drawn by using Stata14.0 software,and then a network meta-analysis on clinical effective rate,knee pain visual analogue scale(VAS)score and Western Ontario and McMaster Universities osteoarthritis index(WOMAC)score was conducted by using ADDIS1.16.6 software,furthermore,the efficacies of the interventions were ranked in accordance with the probability of being the best intervention(Rank1 probability).Results:Three thousand one hundred and twenty-three articles were searched out.After screening,40 articles were included in the final analysis,involving glucocorticoid(GC),ozone(O3),sodium hyaluronate(SH),platelet rich plasma(PRP),mesenchymal stem cell(MSC),PRP+SH,O3+SH,SH+GC,ketorolac tromethamine(KT)+SH,MSC+PRP and normal saline(NS)that used as placebo.The clinical effective rate was reported in 22 researches,involving 9 interventions.Their efficacies for treatment of KOA were ranked from best to worst in accordance with the clinical effective rate,and the results of ranking revealed that the PRP+SH(Rank1 probability=0.38)behaved best in treatment of KOA,followed by O3+SH(Rank1 probability=0.34),SH+GC(Rank1 probability=0.18),MSC+PRP(Rank1 probability=0.05),KT+SH(Rank1 probability=0.03),PRP(Rank1 probability=0.02),SH(Rank1 probability=0.00),O3(Rank1 probability=0.00)and GC(Rank1 probability=0.00)(in no particular order for the last three).The knee pain VAS score was reported in 29 researches,involving 10 interventions.Their efficacies for treatment of KOA were ranked from best to worst in accordance with the knee pain VAS scores,and the results of ranking revealed that the PRP+SH(Rank1 probability=0.43)behaved best in treatment of KOA,followed by O3+SH(Rank1 probability=0.25),O3(Rank1 probability=0.12),KT+SH(Rank1 probability=0.07),MSC(Rank1 probability=0.06),MSC+PRP(Rank1 probability=0.04),SH+GC(Rank1 probability=0.02),GC(Rank1 probability=0.01),PRP(Rank1 probability=0.00)and SH(Rank1 probability=0.00)(in no particular order for the last two).The WOMAC score was reported in 16 researches,involving 9 interventions.Their efficacies for treatment of KOA were ranked from best to worst in accordance with the WOMAC scores,and the results of ranking revealed that the PRP+SH(Rank1 probability=0.42)behaved best in treatment of KOA,followed by O3+SH(Rank1 probability=0.20),MSC+PRP(Rank1 probability=0.18),MSC(Rank1 probability=0.12),KT+SH(Rank1 probability=0.04),NS(Rank1 probability=0.03),PRP(Rank1 probability=0.00),SH(Rank1 probability=0.00)and GC(Rank1 probability=0.00)(in no particular order for the last three).Conclusion:Available evidences suggest that the combined drugs should be used firstly for knee intra-articular injection in treatment of KOA,and SH combined with PRP or O3 behaves better in efficacy.

參考文獻(xiàn)/References:

[1] 中華醫(yī)學(xué)會骨科學(xué)分會關(guān)節(jié)外科學(xué)組,中國醫(yī)師協(xié)會骨科醫(yī)師分會骨關(guān)節(jié)炎學(xué)組,國家老年疾病臨床醫(yī)學(xué)研究中心(湘雅醫(yī)院),等.中國骨關(guān)節(jié)炎診療指南(2021年版)[J].中華骨科雜志,2021,41(18):1291-1314.
[2] 趙曉明,張銀剛,李艷艷.膝骨關(guān)節(jié)炎的階梯化治療研究進(jìn)展[J].現(xiàn)代中西醫(yī)結(jié)合雜志,2021,30(30):3410-3415.
[3] JÜNI P,HARI R,RUTJES A W,et al.Intra-articular corticosteroid for knee osteoarthritis[J].Cochrane Database Syst Rev,2015(10):5328.
[4] FELLER J.Platelet-rich plasma injections were not better than hyaluronic acid injections for knee joint degeneration[J].J Bone Joint Surg Am,2016,98(4):315.
[5] PAS H I,WINTERS M,HAISMA H J,et al.Stem cell injections in knee osteoarthritis:a systematic review of the literature[J].Br J Sports Med,2017,51(15):1125-1133.
[6] 杜一峰,楊永菊,關(guān)雪峰.膝骨性關(guān)節(jié)炎關(guān)節(jié)腔內(nèi)注射治療研究進(jìn)展[J].遼寧中醫(yī)藥大學(xué)學(xué)報,2020,22(6):133-136.
[7] 陳蔚,郭燕梅,李曉英,等.西安大略和麥克馬斯特大學(xué)骨關(guān)節(jié)炎指數(shù)的重測信度[J].中國康復(fù)理論與實踐,2010,16(1):23-24.
[8] HIGGINS J,GREEN S.Cochrane handbook for systematic reviews of interventions:version 5.1.0[EB/OL].(2011-03-01)[2022-01-01].https://handbook-5-1.cochrane.org.
[9] SMITH T C,SPIEGELHALTER D J,THOMAS A.Bayesian approaches to random-effects meta-analysis:a comparative study[J].Stat Med,1995,14(24):2685-2699.
[10] LIN K Y,YANG C C,HSU C J,et al.Intra-articular injection of platelet-rich plasma is superior to hyaluronic acid or saline solution in the treatment of mild to moderate knee osteoarthritis:a randomized,double-blind,triple-parallel,placebo-controlled clinical trial[J].Arthroscopy,2019,35(1):106-117.
[11] LOUIS M L,MAGALON J,JOUVE E,et al.Growth factors levels determine efficacy of platelets rich plasma injection in knee osteoarthritis:a randomized double blind noninferiority trial compared with viscosupplementation[J].Arthroscopy,2018,34(5):1530-1540.
[12] LU L,DAI C,ZHANG Z,et al.Treatment of knee osteoarthritis with intra-articular injection of autologous adipose-derived mesenchymal progenitor cells:a prospective, randomized,double-blind,active-controlled,phase IIb clinical trial[J].Stem Cell Res Ther,2019,10(1):143.
[13] SU K,BAI Y,WANG J,et al.Comparison of hyaluronic acid and PRP intra-articular injection with combined intra-articular and intraosseous PRP injections to treat patients with knee osteoarthritis[J].Clin Rheumatol,2018,37(5):1341-1350.
[14] 曾佳森,張亞勤,周亮,等.富血小板血漿對膝骨關(guān)節(jié)炎相關(guān)細(xì)胞因子的影響[J].中華關(guān)節(jié)外科雜志(電子版),2020,14(2):137-143.
[15] 劉步云,孫育良,何本祥,等.關(guān)節(jié)腔注射富血小板血漿與玻璃酸鈉治療膝關(guān)節(jié)骨關(guān)節(jié)炎的療效比較[J].實用骨科雜志,2017,23(1):71-73.
[16] 楊茂修.玻璃酸鈉關(guān)節(jié)腔注射治療膝骨性關(guān)節(jié)炎探討[J].實用臨床醫(yī)藥雜志,2018,22(19):46-49.
[17] 孟濤,蘇晨.玻璃酸鈉聯(lián)合臭氧治療膝關(guān)節(jié)骨性關(guān)節(jié)炎的近期臨床療效觀察[J].重慶醫(yī)學(xué),2018,47(24):3184-3187.
[18] 譚志韻.玻璃酸鈉關(guān)節(jié)腔注射對膝關(guān)節(jié)骨性關(guān)節(jié)炎患者預(yù)后的影響[J].數(shù)理醫(yī)藥學(xué)雜志,2016,29(7):976-977.
[19] 藺偉,李瑞欣,宋振,等.PRP與玻璃酸鈉注射治療膝骨性關(guān)節(jié)炎的對比研究[J].雙足與保健,2018,27(19):131-132.
[20] 魏軍營.玻璃酸鈉聯(lián)合酮咯酸氨丁三醇關(guān)節(jié)腔內(nèi)注射對膝骨性關(guān)節(jié)炎的療效[J].河南醫(yī)學(xué)研究,2020,29(7):1274-1275.
[21] 賴子云,李廣海,黃浩.玻璃酸鈉與復(fù)方倍他米松關(guān)節(jié)腔內(nèi)給藥對膝關(guān)節(jié)骨性關(guān)節(jié)炎患者的療效及其對膝關(guān)節(jié)功能的影響[J].抗感染藥學(xué),2017,14(1):230-232.
[22] 張言言,李夢霞,楊春燕.玻璃酸鈉聯(lián)合復(fù)方倍他米松注射液治療膝關(guān)節(jié)骨性關(guān)節(jié)炎的臨床效果觀察[J].臨床合理用藥雜志,2019,12(17):85-86.
[23] 梁本高.玻璃酸鈉聯(lián)合復(fù)方倍他米松對膝關(guān)節(jié)骨性關(guān)節(jié)炎患者膝關(guān)節(jié)功能的影響[J].慢性病學(xué)雜志,2017,18(4):463-465.
[24] 柯陳榮,張睿,薛繼鑫.富血小板血漿聯(lián)合透明質(zhì)酸關(guān)節(jié)腔內(nèi)注射治療膝骨關(guān)節(jié)炎療效分析[J].中華全科醫(yī)學(xué),2016,14(11):1810-1812.
[25] 袁林,郭燕慶,于洪波,等.富血小板血漿治療Ⅱ-Ⅲ期膝骨關(guān)節(jié)炎的療效評價[J].中華關(guān)節(jié)外科雜志(電子版),2016,10(4):386-392.
[26] 岳石鎖.關(guān)節(jié)腔注射療法治療膝骨性關(guān)節(jié)炎的臨床療效比照觀察[J].中國醫(yī)藥指南,2016,14(23):166-167.
[27] 陸斌,李建武,楊艷,等.臭氧聯(lián)合玻璃酸鈉對膝關(guān)節(jié)骨性關(guān)節(jié)炎患者膝關(guān)節(jié)功能及疼痛癥狀的改善效果觀察[J].臨床和實驗醫(yī)學(xué)雜志,2018,17(11):1186-1189.
[28] 李明,倪建龍.臭氧聯(lián)合玻璃酸鈉關(guān)節(jié)腔注射治療膝骨關(guān)節(jié)炎療效研究[J].陜西醫(yī)學(xué)雜志,2019,48(9):1216-1219.
[29] 劉大輝.復(fù)方倍他米松注射液聯(lián)合玻璃酸鈉關(guān)節(jié)腔內(nèi)注射治療膝骨性關(guān)節(jié)炎患者的療效分析[J].醫(yī)學(xué)理論與實踐,2020,33(10):1630-1631.
[30] 姜波.富血小板血漿聯(lián)合玻璃酸鈉關(guān)節(jié)內(nèi)注射對膝骨關(guān)節(jié)炎膝關(guān)節(jié)功能及疼痛的影響[J].內(nèi)蒙古醫(yī)學(xué)雜志,2020,52(7):841-842.
[31] 哈承志,李偉,任少達(dá),等.富血小板血漿聯(lián)合間充質(zhì)干細(xì)胞治療膝骨關(guān)節(jié)炎的療效[J].中華關(guān)節(jié)外科雜志(電子版),2018,12(5):644-652.
[32] 馮方,孫育良.關(guān)節(jié)內(nèi)注射富血小板血漿治療膝關(guān)節(jié)骨關(guān)節(jié)炎25例[J].中國臨床研究,2017,30(10):1378-1380.
[33] 馬馳蛟.關(guān)節(jié)腔內(nèi)注射富血小板血漿與透明質(zhì)酸治療膝骨關(guān)節(jié)炎療效觀察[J].山西醫(yī)藥雜志,2018,47(17):2083-2085.
[34] 賀承偉.關(guān)節(jié)腔注射富血小板血漿對膝關(guān)節(jié)骨性關(guān)節(jié)炎的治療效果[J].特別健康,2019(19):231.
[35] 宋雪,楊大偉,畢春強(qiáng),等.酮咯酸氨丁三醇關(guān)節(jié)腔內(nèi)注射對膝骨性關(guān)節(jié)炎患者鎮(zhèn)痛作用研究[J].世界中西醫(yī)結(jié)合雜志,2017,12(11):1528-1531.
[36] 呼宏莉.酮咯酸氨丁三醇聯(lián)合透明質(zhì)酸鈉關(guān)節(jié)腔內(nèi)注射治療膝骨性關(guān)節(jié)炎患者的臨床研究[J].首都食品與醫(yī)藥,2019,26(21):64.
[37] 程文丹,徐生林,吳小三,等.自體骨髓間充質(zhì)干細(xì)胞復(fù)合富血小板血漿治療早期膝關(guān)節(jié)骨關(guān)節(jié)炎療效觀察[J].中華全科醫(yī)學(xué),2019,17(10):1652-1655.
[38] 王建剛.玻璃酸鈉與曲安奈德腔內(nèi)注射對骨性關(guān)節(jié)炎患者功能康復(fù)的影響觀察[J].中外醫(yī)學(xué)研究,2018,16(30):162-163.
[39] 鄭安祥,黃林升.臭氧灌注聯(lián)合透明質(zhì)酸鈉注射對膝骨關(guān)節(jié)炎患者疼痛程度及關(guān)節(jié)液中相關(guān)介質(zhì)的影響[J].臨床合理用藥雜志,2016,9(35):61-62.
[40] 孫曉飛,田軍濤,王世臣.臭氧聯(lián)合玻璃酸鈉關(guān)節(jié)腔注射治療膝骨性關(guān)節(jié)炎的療效評估[J].罕少疾病雜志,2020,27(4):52-53.
[41] 吳迪,蘇云,邱士超,等.臭氧配合玻璃酸鈉關(guān)節(jié)腔注射治療對膝骨關(guān)節(jié)炎患者關(guān)節(jié)功能、疼痛程度及前列腺素E2、白細(xì)胞介素-1β、腫瘤壞死因子-α的影響[J].中國藥物經(jīng)濟(jì)學(xué),2019,14(3):90-92.
[42] 周強(qiáng),劉凱凱,李娜.富血小板血漿、透明質(zhì)酸鈉或曲安奈德治療膝骨關(guān)節(jié)炎的療效分析[J].心理月刊,2020,15(17):210-211.
[43] 孫曉輝,閆宏林,任浩,等.關(guān)節(jié)腔內(nèi)注射倍他米松和玻璃酸鈉治療老年膝關(guān)節(jié)炎的臨床療效[J].臨床醫(yī)學(xué)研究與實踐,2018,3(33):74-75.
[44] 張忠良,林俊宏.關(guān)節(jié)腔內(nèi)注射自體富血小板血漿治療膝骨性關(guān)節(jié)炎療效觀察[J].浙江中西醫(yī)結(jié)合雜志,2017,27(11):951-954.
[45] 謝磊,劉佳,王華軍,等.關(guān)節(jié)腔注射透明質(zhì)酸及富血小板血漿對老年膝骨關(guān)節(jié)炎的治療作用比較[J].中國老年學(xué)雜志,2018,38(5):1129-1131.
[46] 閆亞璞.酮咯酸氨丁三醇聯(lián)合透明質(zhì)酸鈉關(guān)節(jié)腔內(nèi)注射對膝骨性關(guān)節(jié)炎患者VAS評分及生活質(zhì)量的影響[J].現(xiàn)代診斷與治療,2019,30(9):1439-1440.
[47] 葉曉歌,尤良軍.酮咯酸氨丁三醇聯(lián)合透明質(zhì)酸鈉關(guān)節(jié)腔內(nèi)注射治療膝骨性關(guān)節(jié)炎的效果[J].河南醫(yī)學(xué)研究,2019,28(3):473-474.
[48] 趙新亮.透明質(zhì)酸鈉注射配合自體富血小板血漿注射治療膝骨關(guān)節(jié)炎的臨床效果[J].臨床醫(yī)學(xué)研究與實踐,2018,3(25):37-38.
[49] 張雷.自體富血小板血漿(PRP)聯(lián)合玻璃酸鈉關(guān)節(jié)腔注射治療膝關(guān)節(jié)骨性關(guān)節(jié)的臨床療效分析[J].中國合理用藥探索,2019,16(9):47-49.
[50] 中國中醫(yī)藥研究促進(jìn)會骨傷科分會.膝骨關(guān)節(jié)炎中醫(yī)診療指南(2020年版)[J].中醫(yī)正骨,2020,32(10):1-14.
[51] 中華醫(yī)學(xué)會骨科學(xué)分會關(guān)節(jié)外科學(xué)組.骨關(guān)節(jié)炎診療指南(2018年版)[J].中華骨科雜志,2018,38(12):705-715.

相似文獻(xiàn)/References:

[1]樊慶陽,任凱晶.定制3D打印切模輔助全膝關(guān)節(jié)置換術(shù)治療 膝骨關(guān)節(jié)炎合并股骨干骨折畸形愈合[J].中醫(yī)正骨,2015,27(11):37.
[2]劉曉雅,孫永強(qiáng),劉國杰.主動快速康復(fù)鍛煉對全膝關(guān)節(jié)置換術(shù)后關(guān)節(jié)活動度的影響[J].中醫(yī)正骨,2015,27(09):73.
[3]鄭春松,葉蕻芝,李西海,等.透骨消痛膠囊中補(bǔ)腎柔肝藥和活血祛風(fēng)藥治療 骨關(guān)節(jié)炎作用方式的計算機(jī)模擬比較[J].中醫(yī)正骨,2015,27(07):6.
　ZHENG Chunsong,YE Hongzhi,LI Xihai,et al.Comparison of the mode of action of Bushen Rougan(補(bǔ)腎柔肝)drugs versus Huoxue Qufeng(活血祛風(fēng))drugs contained in Tougu Xiaotong Jiaonang(透骨消痛膠囊)for the treatment of osteoarthritis:A computer simulation study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):6.
[4]宋兵華,孫俊英,倪增良,等.全膝關(guān)節(jié)置換術(shù)前CT測量股骨后髁角的臨床意義[J].中醫(yī)正骨,2015,27(07):38.
[5]鄭春松,葉蕻芝,李西海,等.獨活寄生湯含藥血清對白細(xì)胞介素1β誘導(dǎo)的 退變關(guān)節(jié)軟骨細(xì)胞中基質(zhì)金屬蛋白酶 和環(huán)氧化酶2表達(dá)的影響[J].中醫(yī)正骨,2015,27(12):1.
　ZHENG Chunsong,YE Hongzhi,LI Xihai,et al.Impact of Duhuo Jisheng Tang(獨活寄生湯)medicated serum on expression of matrix metalloproteinase and cyclooxygenase 2 in degenerative articular chondrocytes induced by interleukin-1 beta[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):1.
[6]王金良,孫京濤,李玲,等.骨水泥聯(lián)合螺釘修復(fù)全膝關(guān)節(jié)置換術(shù)中 脛骨平臺內(nèi)側(cè)骨缺損[J].中醫(yī)正骨,2015,27(12):55.
[7]馮榮,王平,李炳奇,等.鈹針刺絡(luò)拔罐結(jié)合中藥口服治療膝骨關(guān)節(jié)炎合并 原發(fā)性血小板增多癥1例[J].中醫(yī)正骨,2015,27(12):73.
[8]蔡云仙.圍手術(shù)期耳穴按壓聯(lián)合平衡針療法 在全膝關(guān)節(jié)置換術(shù)后鎮(zhèn)痛中的應(yīng)用[J].中醫(yī)正骨,2015,27(06):41.
[9]張榮,王健.人工全膝關(guān)節(jié)置換術(shù)的圍手術(shù)期心理護(hù)理[J].中醫(yī)正骨,2015,27(05):77.
[10]喻長純,楊明路,王戰(zhàn)朝.不同手術(shù)方式治療脛骨平臺骨折畸形愈合的體會[J].中醫(yī)正骨,2015,27(03):37.
[11]孟維娜,明立功,王新德,等.關(guān)節(jié)鏡下清理聯(lián)合腓骨近1/3段截骨治療膝骨關(guān)節(jié)炎[J].中醫(yī)正骨,2015,27(11):40.
[12]明立功,孟維娜,王新德,等.腓骨近端截骨治療內(nèi)側(cè)間室膝骨關(guān)節(jié)炎的近期療效觀察[J].中醫(yī)正骨,2015,27(10):25.
[13]張杰,王人彥,張玉柱.膝骨關(guān)節(jié)炎的治療進(jìn)展[J].中醫(yī)正骨,2015,27(10):68.
[14]梁朝,蔡靜怡,閆立,等.針刀療法改善膝骨關(guān)節(jié)炎早期疼痛癥狀的療效評價[J].中醫(yī)正骨,2015,27(09):9.
　LIANG Zhao,CAI Jingyi,YAN Li,et al.Evaluation of the curative effect of needle-knife therapy for relieving knee pain in patients with early knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):9.
[15]王建武,黨建軍,李強(qiáng),等.四聯(lián)療法治療膝骨關(guān)節(jié)炎[J].中醫(yī)正骨,2015,27(08):44.
[16]劉紅娟,郭會利,郭樹農(nóng).云克聯(lián)合中藥治療膝骨關(guān)節(jié)炎的護(hù)理[J].中醫(yī)正骨,2015,27(08):75.
[17]陳衛(wèi)衡.探索建立系統(tǒng)的膝骨關(guān)節(jié)炎中醫(yī)臨床科研范式 和理論體系[J].中醫(yī)正骨,2015,27(07):1.
[18]帥波,沈霖,楊艷萍,等.加味青娥丸治療膝骨關(guān)節(jié)炎的作用機(jī)制研究[J].中醫(yī)正骨,2015,27(07):15.
　SHUAI Bo,SHEN Lin,YANG Yanping,et al.Study on the mechanism of action of Jiawei Qing'e Wan(加味青娥丸)for the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):15.
[19]梅其杰,袁長深,段戡,等.壯藥骨痹方燙熨聯(lián)合運(yùn)動療法治療膝骨關(guān)節(jié)炎的臨床研究[J].中醫(yī)正骨,2015,27(07):27.
　MEI Qijie,YUAN Changshen,DUAN Kan,et al.Clinical study of the curative effect of hot compressing and rubbing with packet of Gubi Fang(骨痹方)combined with exercise therapy in the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):27.
[20]王丹輝,張燕,劉麗娟,等.重組人Ⅱ型腫瘤壞死因子受體-抗體融合蛋白 關(guān)節(jié)腔注射聯(lián)合中藥薰洗治療膝骨關(guān)節(jié)炎的臨床研究[J].中醫(yī)正骨,2015,27(07):31.
　WANG Danhui,ZHANG Yan,LIU Lijuan,et al.Clinical study on intra-articular injection of TypeⅡrecombinant human tumor necrosis factor receptor-Fc fusion protein combined with Chinese herbal steaming and washing therapy for treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):31.

備注/Memo

備注/Memo:
基金項目:河南省中醫(yī)藥科學(xué)研究專項課題(2017ZY2044,2019ZYBJ06) 通訊作者:汪利合 E-mail:wanglihe0222@sina.com
更新日期/Last Update: 1900-01-01