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[1]李俊,陳勇,劉明,等.冰酥腫痛酊外用治療踝關(guān)節(jié)閉合性骨折早期腫痛的臨床研究[J].中醫(yī)正骨,2022,34(05):13-16.
　LI Jun,CHEN Yong,LIU Ming,et al.A clinical study of external application of Bingsu Zhongtong(冰酥腫痛)tincture for treatment of early swelling and pain resulting from closed ankle fractures[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2022,34(05):13-16.
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冰酥腫痛酊外用治療踝關(guān)節(jié)閉合性骨折早期腫痛的臨床研究()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第34卷
期數(shù):
2022年05期
頁碼:
13-16
欄目:
臨床研究
出版日期:
2022-05-20

文章信息/Info

Title:
A clinical study of external application of Bingsu Zhongtong(冰酥腫痛)tincture for treatment of early swelling and pain resulting from closed ankle fractures
作者:
李俊1; 陳勇1; 劉明1; 黃路璽1; 段超1; 鄧超1; 車國良1; 馬強2; 周細江1
(1.長沙市中醫(yī)醫(yī)院/長沙市第八醫(yī)院,湖南 長沙 410002; 2.湖南中醫(yī)藥大學(xué),湖南 長沙 410208)
Author(s):
LI Jun1; CHEN Yong1; LIU Ming1; HUANG Luxi1; DUAN Chao1; DENG Chao1; CHE Guoliang1; MA Qiang2; ZHOU Xijiang1
1.Changsha Hospital of TCM(The Eighth Hospital of Changsha),Changsha 410002,Hunan,China2.Hunan University of Chinese Medicine,Changsha 410208,Hunan,China
關(guān)鍵詞:
踝部骨折;  骨折; 閉合性;  腫脹;  疼痛;  冰酥腫痛酊;  臨床試驗
Keywords:
ankle fractures;  fractures; closed;  swelling;  pain;  Bingsu Zhongtong tincture;  clinical trial
摘要:
目的:觀察冰酥腫痛酊外用治療踝關(guān)節(jié)閉合性骨折早期腫痛的臨床療效。方法:將90例符合要求的閉合性踝關(guān)節(jié)骨折患者隨機分為3組,每組30例。冰敷組予以腫脹處冰敷、患肢石膏固定制動、患肢抬高、功能鍛煉等處理; 雪上花搽劑組在冰敷組處理的基礎(chǔ)上,在腫脹處外敷雪上花搽劑,每次5 mL,每天3次; 冰酥腫痛酊組在冰敷組處理的基礎(chǔ)上,在腫脹處外敷冰酥腫痛酊,每次3～5 mL,每天3次。3組均治療至腫脹消退。比較3組患者的腫脹持續(xù)時間、消腫速度、踝關(guān)節(jié)疼痛視覺模擬量表(visual analogue scale,VAS)評分。結(jié)果:①腫脹持續(xù)時間。3組患者的腫脹持續(xù)時間比較,差異有統(tǒng)計學(xué)意義[(10.13±0.96)d,(8.03±0.91)d,(9.70±0.66)d,F=61.967,P=0.000]; 冰敷組的腫脹持續(xù)時間比雪上花搽劑組和冰酥腫痛酊組長(P=0.000; P=0.000); 雪上花搽劑組和冰酥腫痛酊組的腫脹持續(xù)時間比較,差異無統(tǒng)計學(xué)意義(P=0.067)。②消腫速度。3組患者的消腫速度比較,差異有統(tǒng)計學(xué)意義[(0.35±0.09)cm·d-1,(0.44±0.08)cm·d-1,(0.50±0.10)cm·d-1,F=17.816,P=0.000]; 冰敷組的消腫速度比雪上花搽劑組和冰酥腫痛酊組慢(P=0.000; P=0.000); 雪上花搽劑組和冰酥腫痛酊組的消腫速度比較,差異無統(tǒng)計學(xué)意義(P=0.625)。③踝關(guān)節(jié)疼痛VAS評分。治療前3組患者的踝關(guān)節(jié)疼痛VAS評分比較,差異無統(tǒng)計學(xué)意義[(8.07±0.57)分,(8.10±0.54)分,(8.17±0.58)分,F=7.630,P=0.120]。治療結(jié)束后3組患者的踝關(guān)節(jié)疼痛VAS評分均較治療前減小(t=1.256,P=0.000; t=2.575,P=0.000; t=1.360,P=0.000)。治療結(jié)束后3組患者的踝關(guān)節(jié)疼痛VAS評分比較,差異有統(tǒng)計學(xué)意義[(1.93±0.63)分,(1.90±0.47)分,(1.80±0.48)分,F=18.714,P=0.045]; 冰敷組與雪上花搽劑組比較,差異無統(tǒng)計學(xué)意義(P=0.240); 冰敷組和雪上花搽劑組的踝關(guān)節(jié)疼痛VAS評分均高于冰酥腫痛酊組(P=0.001; P=0.000)。結(jié)論:在冰敷的基礎(chǔ)上采用冰酥腫痛酊外用治療踝關(guān)節(jié)閉合性骨折早期腫痛,療效確切,其療效優(yōu)于單純冰敷和冰敷聯(lián)合雪上花搽劑外用。
Abstract:
Objective:To observe the clinical outcome of external application of Bingsu Zhongtong(冰酥腫痛,BSZT)tincture in treatment of early swelling and pain resulting from closed ankle fractures.Methods:Ninety patients with closed ankle fractures were enrolled in the study and were randomly divided into ice compress group,Xueshanghua(雪上花,XSH)liniment group and BSZT tincture group,30 cases in each group.All patients in the 3 groups were treated with the conventional treatments such as ice compress at the swelling parts,plaster fixing,braking and raising the injured limbs and functional exercises.Moreover,the patients in XSH liniment group were further treated with external application of XSH liniment at the swelling parts,3 times a day,5 mL at a time; and the ones in BSZT tincture group with external application of BSZT tincture at the swelling parts,3 times a day,3-5 mL at a time.All patients in the 3 groups were treated till the swelling was subsided and skin folds appeared in ankle.The ankle swelling duration,detumescence speed and ankle pain visual analogue scale(VAS)score were compared between the 3 groups.Results:①There was statistical difference in ankle swelling duration between the 3 groups(10.13±0.96,8.03±0.91,9.70±0.66 days,F=61.967,P=0.000).The ankle swelling duration was longer in ice compress group compared to XSH liniment group and BSZT tincture group(P=0.000,P=0.000),while there was no statistical difference between XSH liniment group and BSZT tincture group(P=0.067).②There was statistical difference in detumescence speed between the 3 groups(0.35±0.09,0.44±0.08,0.50±0.10 cm/d,F=17.816,P=0.000).The detumescence speed was slower in ice compress group compared to XSH liniment group and BSZT tincture group(P=0.000; P=0.000),while there was no statistical difference between XSH liniment group and BSZT tincture group(P=0.625).③There was no statistical difference in ankle pain VAS score between the 3 groups before the treatment(8.07±0.57,8.10±0.54,8.17±0.58 points,F=7.630,P=0.120).The ankle pain VAS scores decreased in the 3 groups after the end of the treatment compared to pre-treatment(t=1.256,P=0.000; t=2.575,P=0.000; t=1.360,P=0.000).There was statistical difference in ankle pain VAS score between the 3 groups after the end of the treatment(1.93±0.63,1.90±0.47,1.80±0.48 points,F=18.714,P=0.045).The ankle pain VAS scores were not significantly different from each other between ice compress group and XSH liniment group(P=0.240),whereas it was lower in BSZT tincture group compared to compress group and XSH liniment group(P=0.001; P=0.000).Conclusion:Combination of ice compress with external application of BSZT tincture has reliable curative effects in treatment of early swelling and pain resulting from closed ankle fractures,and it surpasses the monotherapy of ice compress and the combination therapy of ice compress and external application of XSH liniment in curative effects.

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(收稿日期:2021-08-12 本文編輯:李曉樂)

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備注/Memo

備注/Memo:
基金項目:湖南省中醫(yī)藥科研計劃項目(2019136) 通訊作者:周細江 E-mail:[email protected]
更新日期/Last Update: 1900-01-01