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[1]忻岳軍,鄭劼.類風(fēng)濕關(guān)節(jié)炎MRI評分系統(tǒng)評價類風(fēng)濕關(guān)節(jié)炎疾病活動度的應(yīng)用價值[J].中醫(yī)正骨,2022,34(01):47-49.
　XIN Yuejun,ZHENG Jie.Application value of rheumatoid arthritis MRI scoring system in assessment of disease activity in patients with rheumatoid arthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2022,34(01):47-49.
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類風(fēng)濕關(guān)節(jié)炎MRI評分系統(tǒng)評價類風(fēng)濕關(guān)節(jié)炎疾病活動度的應(yīng)用價值()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第34卷
期數(shù):
2022年01期
頁碼:
47-49
欄目:
臨床研究
出版日期:
2022-01-20

文章信息/Info

Title:
Application value of rheumatoid arthritis MRI scoring system in assessment of disease activity in patients with rheumatoid arthritis
作者:
忻岳軍1; 鄭劼2
(1.寧波市第六醫(yī)院,浙江 寧波 315040; 2.浙江省人民醫(yī)院,浙江 杭州 310014)
Author(s):
XIN Yuejun1; ZHENG Jie2
1.Ningbo No.6 Hospital,Ningbo 315040,Zhejiang,China;2.Zhejiang Provincial People’s Hospital,Hangzhou 310014,Zhejiang,China
關(guān)鍵詞:
關(guān)節(jié)炎; 類風(fēng)濕;  腕關(guān)節(jié);  磁共振成像;  疾病活動度
Keywords:
arthritis; rheumatoid;  wrist joint;  magnetic resonance imaging;  disease activity
摘要:
目的:探討類風(fēng)濕關(guān)節(jié)炎MRI評分系統(tǒng)(rheumatoid arthritis MRI scoring system,RAMRIS)評價類風(fēng)濕關(guān)節(jié)炎(rheumatoid arthritis,RA)疾病活動度的應(yīng)用價值。方法:納入98例RA患者,從病歷系統(tǒng)中提取基于28個關(guān)節(jié)計數(shù)和C反應(yīng)蛋白血清含量的疾病活動度評分(disease activity score 28-C reactive protein,DAS28-CRP)及患者腕關(guān)節(jié)MRI檢查結(jié)果。由2名影像專業(yè)副主任醫(yī)師共同查閱患者腕關(guān)節(jié)MRI檢查結(jié)果,采用RAMRIS評價患者腕部滑膜炎、骨髓水腫及骨侵蝕情況,記錄滑膜炎評分、骨侵蝕評分、骨髓水腫評分及RAMRIS總分。分析2名醫(yī)師對RA患者腕關(guān)節(jié)評價結(jié)果的一致性及各評分與DAS28-CRP的相關(guān)性,采用受試者操作特征曲線評價RAMRIS評價RA疾病活動度的應(yīng)用價值。結(jié)果:2名醫(yī)師對RA患者腕關(guān)節(jié)的MRI評價結(jié)果(滑膜炎評分、骨髓水腫評分、骨侵蝕評分、RAMRIS總分)的一致性較好(Kappa=0.788,P=0.000; Kappa=0.852,P=0.013; Kappa=0.787,P=0.000; Kappa=0.627,P=0.001)。Pearson相關(guān)性分析結(jié)果顯示滑膜炎評分、骨髓水腫評分、骨侵蝕評分、RAMRIS總分均與DAS28-CRP呈正相關(guān)(r=0.471,P=0.024; r=0.321,P=0.041; r=0.433,P=0.000; r=0.545,P=0.038)。以DAS28-CRP為RA疾病活動度的評價標(biāo)準(zhǔn),滑膜炎評分、骨髓水腫評分、骨侵蝕評分和RAMRIS總分評價RA疾病活動度的受試者操作特征曲線下面積分別為0.786(P=0.000)、0.803(P=0.000)、0.788(P=0.000)、0.812(P=0.000)。結(jié)論:RAMRIS評價RA疾病活動度具有較高的應(yīng)用價值。
Abstract:
Objective:To explore the application value of rheumatoid arthritis magnetic resonance imaging(MRI)scoring system(RAMRIS)in assessment of disease activity in patients with rheumatoid arthritis(RA).Methods:Ninety-eight RA patients were enrolled in the study.The disease activity scores based on 28 joints and C-reactive protein(DAS28-CRP)and the wrist MRI examination outcomes were extracted from the Electronic Medical Record System(EMRS).The MRI outcomes were jointly reviewed by 2 associate chief physicians in medical imaging specialty.The wrist synovitis,bone marrow edema(BME)and bone erosion were assessed by using RAMRIS,and their scores as well as the total RAMRIS score were recorded.The consistency of wrist MRI assessment results between the 2 physicians and the correlation between the scores and DAS28-CRP were analyzed.The applied value of RAMRIS in assessing the disease activity of RA were evaluated by using receiver operating characteristic(ROC)curve.Results:The good consistency in wrist MRI assessment results(synovitis score,BME score,bone erosion score and total RAMRIS score)were found between the 2 physicians(Kappa=0.788,P=0.000; Kappa=0.852,P=0.013; Kappa=0.787,P=0.000; Kappa=0.627,P=0.001).The results of Pearson correlation analysis showed that the scores of synovitis,BME and bone erosion as well as total RAMRIS score were positively correlated with DAS28-CRP(r=0.471,P=0.024; r=0.321,P=0.041; r=0.433,P=0.000; r=0.545,P=0.038).With DAS28-CRP as the evaluation standard,the areas under the ROC curves established based on the scores of synovitis,BME and bone erosion as well as total RAMRIS score for assessing RA disease activity were 0.786(P=0.000),0.803(P=0.000),0.788(P=0.000)and 0.812(P=0.000)respectively.Conclusion:RAMRIS has a high application value in assessment of disease activity in patients with RA.

參考文獻/References:

[1] DE THURAH A,STENGAARD-PEDERSEN K,AXELSEN M,et al.Tele-health followup strategy for tight control of disease activity in rheumatoid arthritis:results of a randomized controlled trial[J].Arthritis Care Res(Hoboken),2018,70(3):353-360.
[2] NACHVAK S M,ALIPOUR B,MAHDAVI A M,et al.Effects of coenzyme Q10 supplementation on matrix metalloproteinases and DAS-28 in patients with rheumatoid arthritis:a randomized,double-blind,placebo-controlled clinical trial[J].Clin Rheumatol,2019,38(12):3367-3374.
[3] M?LLER-BISGAARD S,H?RSLEV-PETERSEN K,EJBJERG B,et al.Effect of magnetic resonance imaging vs conventional treat-to-target strategies on disease activity remission and radiographic progression in rheumatoid arthritis:the IMAGINE-RA randomized clinical trial[J].JAMA,2019,321(5):461-472.
[4] BABAOGLU H,BAYTAROGLU A,TORGUTALP M,et al.Abnormal retinal microvasculature found in active rheumatoid arthritis:a different perspective of microvascular health[J].Turk J Med Sci,2019,49(1):20-26.
[5] AHMAD H A,BAKER J F,?STERGAARD M,et al.Baseline objective inflammation by magnetic resonance imaging as a predictor of therapeutic benefit in early rheumatoid arthritis with poor prognosis[J].Arthritis Care Res(Hoboken),2020,72(7):959-964.
[6] SUNDIN U,AGA A B,SKARE ?,et al.Conventional versus ultrasound treat to target:no difference in magnetic resonance imaging inflammation or joint damage over 2 years in early rheumatoid arthritis[J].Rheumatology(Oxford),2020,59(9):2550-2555.
[7] SEWERIN P,BUCHBENDER C,VORDENB?MEN S,et al.Advantages of a combined rheumatoid arthritis magnetic resonance imaging score(RAMRIS)for hand and feet:does the RAMRIS of the hand alone underestimate disease activity and progression?[J].BMC Musculoskeletal Disorders,2014,15:104.
[8] 中華醫(yī)學(xué)會風(fēng)濕病學(xué)分會.2018中國類風(fēng)濕關(guān)節(jié)炎診療指南[J].中華內(nèi)科雜志,2018,57(4):242-251.
[9] 龐琳烜,鄭朝暉,李治琴,等.超聲及MRI對手及腕部類風(fēng)濕關(guān)節(jié)炎活動性的評估價值[J].中國CT和MRI雜志,2020,18(6):140-142.
[10] BEALS C,BAUMGARTNER R,PETERFY C,et al.Magnetic resonance imaging of the hand and wrist in a randomized,double-blind,multicenter,placebo-controlled trial of infliximab for rheumatoid arthritis:comparison of dynamic contrast enhanced assessments with semi-quantitative scoring[J/OL].PLoS One,2017,12(12)[2021-04-15].https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728526/.
[11] 劉元君.動態(tài)增強MRI和肌骨超聲對類風(fēng)濕關(guān)節(jié)炎活動性的診斷價值比較[J].中國CT和MRI雜志,2021,19(5):173-176.
[12] DALBETH N,SAAG K G,PALMER W E,et al.Effects of Febuxostat in early gout:a randomized,double-blind,placebo-controlled study[J].Arthritis Rheumatol,2017,69(12):2386-2395.
[13] GLINATSI D,BAKER J F,HETLAND M L,et al.Magnetic resonance imaging assessed inflammation in the wrist is associated with patient-reported physical impairment,global assessment of disease activity and pain in early rheumatoid arthritis:longitudinal results from two randomised controlled trials[J].Ann Rheum Dis,2017,76(10):1707-1715.
[14] BAKER J F,CONAGHAN P G,SMOLEN J S,et al.Development and validation of modified disease activity scores in rheumatoid arthritis:superior correlation with magnetic resonance imaging-detected synovitis and radiographic progression[J].Arthritis Rheumatol,2014,66(4):794-802.
[15] M?LLER-BISGAARD S,H?RSLEV-PETERSEN K,EJBJERG B J,et al.Impact of a magnetic resonance imaging-guided treat-to-target strategy on disease activity and progression in patients with rheumatoid arthritis(the IMAGINE-RA trial):study protocol for a randomized controlled trial[J].Trials,2015,16:178.
[16] PLEIN S,ERHAYIEM B,FENT G,et al.Cardiovascular effects of biological versus conventional synthetic disease-modifying antirheumatic drug therapy in treatment-na?e,early rheumatoid arthritis[J].Ann Rheum Dis,2020,79(11):1414-1422.

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更新日期/Last Update: 1900-01-01