84年鼠女哪年财运最旺,857comvvv色九欧美激情|85PO_87国产精品欲av国产av资源

[1]徐道情,黃維琛,歐梁,等.基于中醫(yī)傳承輔助平臺挖掘《正體類要》中治傷內(nèi)服方劑的用藥規(guī)律[J].中醫(yī)正骨,2021,33(12):14-18.
　XU Daoqing,HUANG Weichen,OU Liang,et al.A data mining-based analysis of clinical medication rules of oral prescriptions for treatment of orthopedic and traumatic diseases in Classification and Treatment of Traumatic Diseases using traditional Chinese medicine inheritance support system[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2021,33(12):14-18.
點擊復(fù)制

基于中醫(yī)傳承輔助平臺挖掘《正體類要》中治傷內(nèi)服方劑的用藥規(guī)律()
分享到：

《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第33卷
期數(shù):
2021年12期
頁碼:
14-18
欄目:
文獻研究
出版日期:
2021-12-20

文章信息/Info

Title:
A data mining-based analysis of clinical medication rules of oral prescriptions for treatment of orthopedic and traumatic diseases in Classification and Treatment of Traumatic Diseases using traditional Chinese medicine inheritance support system
作者:
徐道情1; 黃維琛2; 歐梁2; 孔德忠1; 楊先宇1; 付興前1
(1.貴州中醫(yī)藥大學(xué)骨傷學(xué)院,貴州 貴陽 550002; 2.貴州中醫(yī)藥大學(xué)第二附屬醫(yī)院,貴州 貴陽 550003)
Author(s):
XU Daoqing1; HUANG Weichen2; OU Liang2; KONG Dezhong1; YANG Xianyu1; FU Xingqian1
1.The College of Traumatology and Orthopedics of Guizhou University of Traditional Chinese Medicine,Guiyang 550002,Guizhou,China2.The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550003,Guizhou,China
關(guān)鍵詞:
中醫(yī)藥學(xué)文獻;  數(shù)據(jù)挖掘;  方劑構(gòu)成;  組方原則;  聚類分析;  正體類要
Keywords:
medicine pharmacologic literature(TCM);  data mining;  constitution of formula;  formula composing principles;  cluster analysis;  Classification and Treatment of Traumatic Diseases
摘要:
目的:挖掘《正體類要》中治傷內(nèi)服方劑的用藥規(guī)律。方法:收集《正體類要》中的治傷內(nèi)服方劑,利用中醫(yī)傳承輔助平臺(V2.5)對數(shù)據(jù)進行統(tǒng)計分析,挖掘方劑的用藥規(guī)律。結(jié)果:共收集到57首方劑,涉及116味中藥,其中出現(xiàn)頻次≥5的中藥有19味,排在前3位的分別是當(dāng)歸、甘草、人參。57首內(nèi)服治傷方劑的組方藥物中,藥性以溫性出現(xiàn)頻次最多、其次為寒性,藥味以甘味出現(xiàn)頻次最多、其次為苦和辛味,歸經(jīng)以脾經(jīng)出現(xiàn)頻次最多、其次為肝經(jīng); 出現(xiàn)頻次≥10的藥物組合有8個,排在前3位的為人參-甘草、人參-茯苓、甘草-茯苓; 核心藥物組合10個,分別為羌活-防風(fēng)-細辛、桃仁-紅花-瓜蔞、茯苓-甘草-大棗等。經(jīng)聚類分析得到新處方5首。結(jié)論:《正體類要》中治傷內(nèi)服方劑多采用性溫、味甘、歸脾經(jīng)的藥物; 核心藥物組合以活血化瘀、解表止痛、益氣補血藥物為主; 以核心藥物組合為基礎(chǔ)聚類出的內(nèi)服治傷新方,可為臨床用藥提供參考,但其療效有待進一步研究。
Abstract:
Objective:To excavate the clinical medication rules of oral prescriptions for treatment of orthopedic and traumatic diseases in Classification and Treatment of Traumatic Diseases.Methods:The oral prescriptions aimed at treating orthopedic and traumatic diseases were extracted from the Classification and Treatment of Traumatic Diseases and were statistically analyzed by using traditional Chinese medicine inheritance support system(TCMISS)software(V2.5)for excavating the clinical medication rules.Results:Fifty-seven oral prescriptions were included in the final analysis,involving 116 Chinese herbs,among which 19 ones displayed a occurrence frequency of≥5,and the top 3 ones with high occurrence frequency included Angelica sinensis,Glycyrrhiza uralensis and Ginseng Radix et Rhizoma.Among the 57 oral prescriptions,the most frequently appeared Chinese herbs were those with a warm property,followed by the ones with a cold property; and the ones with sweet flavors were more preferred,followed by bitter and pungent flavors,and they mainly acted on the spleen meridians and liver meridians.The occurrence frequency were≥10 in 8 herb combinations,and the top 3 ones with high occurrence frequency included Ginseng Radix et Rhizoma-Glycyrrhiza uralensis,Ginseng Radix et Rhizoma-Poria(TCD)and Glycyrrhiza uralensis-Poria(TCD); The cluster analysis on all the included Chinese herbs generated 10 core herb combinations,namely Notopterygii Rhizoma et Radix-Saposhnikoviae Radix-Asari Radix et Rhizoma(TCD),Persicae Semen-Carthamus tinctorius-Trichosanthis Fructus,Poria(TCD)-Glycyrrhiza uralensis-Jujubae Fructus and so on,and 5 new prescriptions were dug out.Conclusion:The Chinese herbs are often the ones presented with warm property and sweet flavor and mainly act on spleen meridians in the oral prescriptions aimed at treating orthopedic and traumatic diseases in Classification and Treatment of Traumatic Diseases,and the core herb combinations are mainly the ones for activating blood and removing stasis,relieving exterior syndrome and alleviating pain as well as tonifying qi and nourishing blood.The new prescriptions clustered based on core herb combinations can provide references for clinical medication,while their curative effects need to be further studied.

參考文獻/References:

[1] 牛永濤,謝林,席志鵬,等.《正體類要》氣血臟腑辨證論治思想初探[J].中醫(yī)正骨,2019,31(7):75-76.
[2] 樓毅杰,黃宇丹,陳凌菲.《正體類要》治瘀法探析[J].中醫(yī)文獻雜志,2018,36(4):15-17.
[3] 張錫純.醫(yī)學(xué)衷中參西錄[M].北京:化學(xué)工業(yè)出版社,2018:224-225.
[4] 黃紅泓,覃日宏,柳賢福.中藥當(dāng)歸的化學(xué)成分分析與藥理作用探究[J].世界最新醫(yī)學(xué)信息文摘,2019,19(58):127.
[5] WEI W L,ZENG R,GU C M,et al.Angelica sinensis in China-a review of botanical profile,ethnopharmacology,phytochemistry and chemical analysis[J].J Ethnopharmacol,2016,190:116-141.
[6] 張介賓.景岳全書[M].北京:人民衛(wèi)生出版社,2007:1198-1201.
[7] HOSSEINZADEH H,NASSIRI-ASL M.Pharmacological effects of glycyrrhiza spp and its bioactive constituents:update and review[J].Phytother Res,2015,29(12):1868-1886.
[8] GUO J,YANG C,YANG J,et al.Glycyrrhizic acid ameliorates cognitive impairment in a rat model of vascular dementia associated with oxidative damage and inhibition of voltage-gated sodium channels[J].CNS Neurol Disord Drug Targets,2016,15(8):1001-1008.
[9] HAN S,SUN L,HE F,et al.Anti-allergic activity of glycyrrhizic acid on IgE-mediated allergic reaction by regulation of allergy-related immune cells[J].Sci Rep,2017,7(1):7222.
[10] 李曉紅,齊云,蔡潤蘭,等.甘草總皂苷抗炎作用機制研究[J].中國實驗方劑學(xué)雜志,2010,16(5):110-113.
[11] KUDO T,OKAMURA S,ZHANG Y,et al.Topical application of glycyrrhizin preparation ameliorates experimentally induced colitis in rats[J].World J Gastroenterol,2011,17(17):2223-2228.
[12] 陳士鐸.本草新編[M].北京:中國中醫(yī)藥出版社,2008:61-64.
[13] 孫睿,張建文,梁輝,等.人參皂苷Rg1對大鼠Ⅲ型前列腺炎血清細胞免疫因子的影響[J].四川中醫(yī),2017,35(2):54-56.
[14] 凌露,楊萍,蓋盛坤,等.人參皂苷Rg1通過自噬抑制Raw264.7巨噬細胞凋亡[J].解剖學(xué)報,2016,47(5):599-606.
[15] 王歡,侯殿東,陳文娜,等.人參多糖對NK92-MI細胞殺傷活性的影響及機制[J].中國民族民間醫(yī)藥,2017,26(9):37-39.
[16] 佟彤,董文茜,梁曉雨,等.人參多糖免疫調(diào)節(jié)作用的實驗研究[J].北京中醫(yī)藥,2016,35(1):41-45.
[17] 賈立云,潘曉華,劉晶,等.人參皂苷Rb1、Re對Aβ_(25-35)誘導(dǎo)SK-N-SH細胞損傷的保護作用[J].山東大學(xué)學(xué)報(醫(yī)學(xué)版),2011,49(4):33-37.
[18] 羅浩銘,王穎,陳英紅,等.人參糖蛋白對Aβ_(25～35)誘導(dǎo)SH-SY5Y細胞凋亡的影響[J].中國老年學(xué)雜志,2016,36(24):6077-6080.
[19] 王擁軍,梁倩倩,崔學(xué)軍,等.調(diào)和氣血法防治慢性筋骨病的應(yīng)用與發(fā)展[J].上海中醫(yī)藥雜志,2017,51(6):1-4.
[20] 李曉鋒,王擁軍,莫文,等.耕耘杏林濟世春秋——施杞教授與石筱山傷科學(xué)術(shù)經(jīng)驗繼承創(chuàng)新[J].上海中醫(yī)藥雜志,2017,51(1):1-4.
[21] 李梴.醫(yī)學(xué)入門[M].北京:人民衛(wèi)生出版社,2006:766-772.
[22] 胡勁松.理傷宜從氣血津精論治[J].中醫(yī)正骨,2005,17(3):49-50.
[23] 高櫻,楊龍飛,翟陽,等.具有活血化瘀功效的中藥藥理作用及機制研究進展[J].中華中醫(yī)藥雜志,2018,33(11):5053-5056.
[24] 陳晨,劉倩,高華.活血化瘀藥藥理作用研究進展[J].中國藥事,2011,25(6):603-605.
[25] 倪強,陳宏偉,姜宏森.活血化瘀方聯(lián)合PFNA內(nèi)固定對股骨粗隆間骨折患者髖關(guān)節(jié)功能和血流變學(xué)的影響[J].長春中醫(yī)藥大學(xué)學(xué)報,2017,33(6):951-954.
[26] 方振林,戴燚,劉軍.活血化瘀湯聯(lián)合VSD負壓引流治療對SandersⅡ型跟骨骨折患者術(shù)后切口愈合及術(shù)后并發(fā)癥的影響[J].四川中醫(yī),2020,38(1):146-149.
[27] 吳鵬飛,王培民,范競.傷科古籍中熏洗方的關(guān)聯(lián)規(guī)則分析[J].吉林中醫(yī)藥,2012,32(3):288-290.
[28] 張立軍.活血化瘀結(jié)合解表發(fā)散法治療急性軟組織損傷療效觀察[J].廣西中醫(yī)藥,2015,38(3):26-27.

相似文獻/References:

[1]李剛,程春生.股骨頭壞死血瘀證癥狀與平樂郭氏正骨方藥藥物組成 最大頻繁關(guān)聯(lián)模式挖掘[J].中醫(yī)正骨,2015,27(04):21.
　LI Gang,CHENG Chunsheng.Maximal frequent association pattern mining for studying the relationship between BLOOD STASIS syndrome in patients with osteonecrosis of femoral head and drug components of Pingle Guo's orthopedics prescription[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(12):21.
[2]林潔,范展彪,劉獻祥.基于數(shù)據(jù)挖掘技術(shù)探討陳可冀《清宮配方集成》中治療骨關(guān)節(jié)炎組方的用藥規(guī)律[J].中醫(yī)正骨,2017,29(11):15.
　LIN Jie,FAN Zhanbiao,LIU Xianxiang.Study on medication rule extracted from prescription for treatment of osteoarthritis in Royal Formulary of Qing Dynasty written by Chen Keji based on data mining techniques[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(12):15.
[3]楊波,袁普衛(wèi),康武林,等.基于數(shù)據(jù)挖掘法探討李堪印教授治療強直性脊柱炎的用藥規(guī)律[J].中醫(yī)正骨,2020,32(11):74.
[4]李文浩,牛逸群,譚明生.基于數(shù)據(jù)挖掘法探討中醫(yī)藥治療脊髓型頸椎病的用藥規(guī)律[J].中醫(yī)正骨,2021,33(01):22.
　LI Wenhao,NIU Yiqun,TAN Mingsheng.A study of medication rule of Traditional Chinese Medicine for treatment of cervical spondylotic myelopathy based on data mining approach[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2021,33(12):22.
[5]顧勇,趙艷明,童培建,等.基于數(shù)據(jù)挖掘法探討中藥復(fù)方治療股骨頭壞死的組方規(guī)律[J].中醫(yī)正骨,2021,33(06):49.
　GU Yong,ZHAO Yanming,TONG Peijian,et al.A study of medication rule of Traditional Chinese Medicine compounds for treatment of osteonecrosis of femoral head based on data mining approach[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2021,33(12):49.
[6]張亞運,許金海,莫文.基于數(shù)據(jù)挖掘法分析腰椎椎管狹窄癥中藥外用方的用藥規(guī)律[J].中醫(yī)正骨,2021,33(08):28.
　ZHANG Yayun,XU Jinhai,MO Wen.Medication rules of external-applied Chinese herbal medicine prescriptions for treatment of lumbar spinal stenosis:a data mining-based analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2021,33(12):28.
[7]趙睿晞,王人彥.張玉柱教授治療腰椎間盤突出癥的用藥規(guī)律分析[J].中醫(yī)正骨,2021,33(08):39.
　ZHAO Ruixi,WANG Renyan.An analysis of clinical medication rules of Professor ZHANG Yuzhu in treatment of lumbar disc herniation[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2021,33(12):39.
[8]張杰,丁權(quán)威,張玉柱,等.基于數(shù)據(jù)挖掘法探討張玉柱教授治療神經(jīng)根型頸椎病的辨證用藥規(guī)律[J].中醫(yī)正骨,2021,33(11):41.
　ZHANG Jie,DING Quanwei,ZHANG Yuzhu,et al.Clinical medication rules of Professor ZHANG Yuzhu in treatment of nerve-root type cervical spondylosis based on syndrome differentiation principles:a data mining-based study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2021,33(12):41.
[9]左世國,李姣姣,向昱陽.《醫(yī)宗金鑒·正骨心法要旨》中骨傷外治處方的用藥規(guī)律分析[J].中醫(yī)正骨,2022,34(02):40.
　ZUO Shiguo,LI Jiaojiao,XIANG Yuyang.Clinical medication rules of the prescriptions for external treatment of orthopedic and traumatic diseases in Yizong Jinjian,Essentials of Bone Orthopedics[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2022,34(12):40.
[10]祁建華,明洪,張會擇,等.基于數(shù)據(jù)挖掘法探討《世醫(yī)得效方》中治傷方劑的用藥規(guī)律[J].中醫(yī)正骨,2022,34(03):20.
　QI Jianhua,MING Hong,ZHANG Huize,et al.A data mining-based analysis of clinical medication rules of prescriptions for treatment of orthopedic and traumatic diseases in Shiyi Dexiao Fang[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2022,34(12):20.
[11]王笑青,張麗麗,沙莎,等.基于中醫(yī)傳承輔助平臺挖掘《辨證錄》中痹病內(nèi)服方劑的組方配伍規(guī)律[J].中醫(yī)正骨,2023,35(06):44.
　WANG Xiaoqing,ZHANG Lili,SHA Sha,et al.A data mining-based analysis of clinical medication rules of oral prescriptions for treatment of Bi-diseases in Syndrome Differentiation Record using traditional Chinese medicine inheritance support system[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2023,35(12):44.
[12]黃明翥,周紅海,何心愉,等.《醫(yī)宗金鑒·正骨心法要旨》中治療傷科瘀腫疼痛方劑的用藥規(guī)律分析[J].中醫(yī)正骨,2023,35(10):37.
　HUANG Mingzhu,ZHOU Honghai,HE Xinyu,et al.A data mining-based analysis of clinical medication rules of traumatologic prescriptions for treatment of blood stasis,swelling and pain in Yizong Jinjian,Essentials of Bone Orthopedics[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2023,35(12):37.
[13]李琰,尹煜輝,劉寧,等.《永類鈐方》中骨傷內(nèi)服藥方的用藥規(guī)律分析[J].中醫(yī)正骨,2024,36(04):47.
　LI Yan,YIN Yuhui,LIU Ning,et al.Clinical medication rules of the oral prescriptions for treatment of orthopedic traumatologic diseases(TCM)in Yonglei Qianfang[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2024,36(12):47.

備注/Memo

備注/Memo:
通訊作者:黃維琛 E-mail:[email protected]
更新日期/Last Update: 1900-01-01