參考文獻(xiàn)/References:
[1] 胡炯,王博,吳鵬,等.CKIP-1與骨質(zhì)疏松的最新研究進(jìn)展[J].中國(guó)骨質(zhì)疏松雜志,2016,22(8):1053-1057.
[2] NIE J,LIU L,XING G,et al.CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation[J].Oncogene,2014,33(28):3677-3687.
[3] TOKUDA E,FUJITA N,OH-HARA T,et al.Casein kinase 2-interacting protein-1,a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo[J].Cancer Res,2007,67(20):9666-9676.
[4] FLORENCIO-SILVA R,DA SILVA SASSO GR,SIMOES MJ,et al.Biology of bone tissue:structure,function,and factors that influence bone cells[J].Biomed Res Int,2015,10(1155):421746-421763.
[5] HOSOKAWA N,HARA T,KAIZUKA T,et al.Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy[J].Mol Biol Cell,2009,20(7):1981-1991.
[6] DIBBLE CC,MANNING BD.Signal integration by mTORC1 coordinates nutrient input with biosynthetic output[J].Nat Cell Biol,2013,15(6):555-564.
[7] HE C,KLIONSKY DJ.Regulation mechanisms and signaling pathways of autophagy[J].Annu Rev Genet,2009,43:67-93.
[8] GANLEY IG,LAM DU H,WANG J,et al.ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy[J].J Biol Chem,2009,284(18):12297-12305.
[9] HOSOKAWA N,SASAKI T,IEMURA SI,et al.Atg101,a novel mammalian autophagy protein interacting with Atg13[J].Autophagy,2009,5(7):973-979.
[10] JUNG HS,CHUNG KW,WON KIM J,et al.Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia[J].Cell Metab,2008,8(4):318-324.
[11] LIU F,FANG F,YUAN H,et al.Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation[J].J Bone Miner Res,2013,28(11):2414-2430.
[12] NOLLET M,SANTUCCI-DARMANIN S,BREUIL V,et al.Autophagy in osteoblasts is involved in mineralization and bone homeostasis[J].Autophagy,2014,10(11):1965-1977.
[13] NIE J,LIU L,HE FC,et al.CKIP-1: A scaffold protein and potential therapeutic target integrating multiple signaling pathways and physiological functions[J].Ageing Res Rev,2013,12(1,213):276-281.
[14] ZAHM AM,BOHENSKY J,ADAMS CS,et al.Bone cell autophagy is regulated by environmental factors[J].Cells Tissues Organs,2011,194(2/4):274-278.
[15] KING JS,VELTMAN DM,INSALL RH.The induction of autophagy by mechanical stress[J].Autophagy,2011,7(12):1490-1499.
[16] JIA J,YAO W,GUAN M,et al.Glucocorticoid dose determines osteocyte cell fate[J].FASEB J,2011,25(10):3366-3376.
[17] DESELM CJ,MILLER BC,ZOU W,et al.Autophagy proteins regulate the secretory component of osteoclastic bone resorption[J].Dev Cell,2011,21(5):966-974.
[18] CEJKA D,HAYER S,NIEDERREITER B,et al.Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis[J].Arthritis Rheum,2010,62(8):2294-2302.
[19] ZHAO Y,CHEN G,ZHANG W,et al.Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1α/BNIP3 signaling pathway[J].J Cell Physiol,2012,227(2):639-648.
[20] SAMBANDAM Y,TOWNSEND MT,PIERCE JJ,et al.Microgravity control of autophagy modulates osteoclastogenesis[J].Bone,2014,61:125-131.
[21] SHI J,WANG L,ZHANG H,et al.Glucocorticoids: dose-related effects on osteoclast formation and function via reactive Oxygen species and autophagy[J].Bone,2015,79:222-232.
[22] GLANTSCHNIG H,FISHER JE,WESOLOWSKI G,et al.M-CSF,TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase[J].Cell Death Differ,2003,10(10):1165–1177.
[23] ERNST M,HEATH JK,SCHMID C,et al.Evidence for a direct effect of estrogen on bone cells in vitro[J].J Steroid Biochem,1989,34(1-6):279-284.
[24] YANG YH,CHEN K,LI B,et al.Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER-ERK-mTOR pathway[J].Apoptosis,2013,18(11):1363-1375.
[25] TCHETINA EV,MASLOVA KA,KRYLOV MY,et al.Association of bone loss with the upregulation of survival-related genes and concomitant downregulation of Mammalian target of rapamycin and osteoblast differentiation-related genes in the peripheral blood of late postmenopausal osteoporotic women[J].J Osteoporos,2015
[2017-10-11].https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338391.
[26] KNEISSEL M,LUONG-NGUYEN NH,BAPTIST M,et al.Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts[J].Bone,2004,35(5):1144-1156.
[27] CHUNG YH,YOON SY,CHOI B,et al.Microtubule-associated protein light chain 3 regulates Cdc42-dependent actin ring formation in osteoclast[J].Int J Biochem Cell Biol,2012,44(6):989-997.
[28] PRIETO-DOMÍNGUEZ N,ORDÓÑEZ R,FERNNDEZ A,et al.Modulation of autophagy by sorafenib:effects on treatment response[J].Front Pharmacol,2016,7:151.
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