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[1]羅明星,劉丙根,羅文禮,等.保肢與截肢治療后骨肉瘤患者肢體功能及生活質量的Meta分析[J].中醫(yī)正骨,2017,29(07):41-45.
　LUO Mingxing,LIU Binggen,LUO Wenli,et al.Comparison of limb salvage and amputation on limb function and life quality of patients with osteosarcoma:a meta analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(07):41-45.
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保肢與截肢治療后骨肉瘤患者肢體功能及生活質量的Meta分析()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第29卷
期數(shù):
2017年07期
頁碼:
41-45
欄目:
文獻研究
出版日期:
2017-07-20

文章信息/Info

Title:
Comparison of limb salvage and amputation on limb function and life quality of patients with osteosarcoma:a meta analysis
作者:
羅明星1; 劉丙根1; 羅文禮1; 付有偉2; 龐清江2
1.浙江省寧波市杭州灣醫(yī)院,浙江 寧波 315010; 2.浙江省寧波市第二醫(yī)院,浙江 寧波 315010
Author(s):
LUO Mingxing1; LIU Binggen1; LUO Wenli1; FU Youwei2; PANG Qingjiang2
1.Hangzhou Bay Hospital of Ningbo City,Ningbo 315010,Zhejiang,China 2.The Second Hospital of Ningbo City,Ningbo 315010,Zhejiang,China
關鍵詞:
骨肉瘤;  截肢術;  保肢治療;  功能恢復;  生活質量;  Meta分析;  系統(tǒng)評價
Keywords:
Key words osteosarcoma;  amputation;  limb salvage;  recovery of function;  quality of life;  Meta-Analysis;  systematic review
摘要:
目的:系統(tǒng)評價保肢與截肢治療后骨肉瘤患者的肢體功能及生活質量。方法:以計算機檢索The Cochrane Library(2016年第12期)、PubMed、Ovid、Spinger Link、Elsevier、CNKI、WanFang Data 1970年1月1日至2016年12月31日所有有關比較保肢與截肢治療后骨肉瘤患者肢體功能及生活質量的中、英文獻,同時手工檢索納入文獻的 參考文獻。由2位研究人員獨立進行文獻檢索、篩選,采用Cochrane協(xié)作網提供的Revman5.0軟件進行Meta分析。結果:共檢出文獻1301篇,經篩選后最終納入10篇文獻,均為英文文獻。總樣本量614例,保肢治療組350例、截肢治療組264例。Meta分析結果顯示,2組患者治療后的多倫多保肢評分系統(tǒng)評分比較,差異無統(tǒng)計學意義[WMD=-0.23,95%CI(-0.82,0.36)]; 保肢組的簡明健康狀況調查表評分高于截肢組[WMD=-0.26,95%CI(-0.46,-0.06)]。結論:與截肢治療相比,采用保肢治療后骨肉瘤患者的生活質量更高,但肢體功能與前者相當。
Abstract:
ABSTRACT Objective:To systematically review limb function and life quality of patients with osteosarcoma after limb salvage and amputation.Methods:All the Chinese and English articles about limb function and life quality of patients with osteosarcoma after limb salvage and amputation included from January 1,1970 to December 31,2016 were retrieved from the Cochrane Library(2016,No.12),PubMed,Ovid,Spinger Link,Elsevier,China national knowledge internet and WanFang Data through computer.Meanwhile,all the references in the included articles were manual retrieved.The articles were searched and screened independently by two researchers.The articles were evaluated by using Cochrane system and a Meta-analysis was conducted by using Revman 5.0 software.Results:One thousand three hundred and one articles were searched out.After screening,10 English articles(614 patients)were included in the final analysis,350 patients in limb salvage group and 264 patients in amputation group.The result of Meta-analysis demonstrated that there was no statistical difference in posttreatment Toronto extremity salvage scores between the 2 groups(WMD=-0.23,95%CI(-0.82,0.36))and the short form 36 health survey questionnaire(SF-36)scores were higher in limb salvage group compared to amputation group(WMD=-0.26,95%CI(-0.46,-0.06)).Conclusion:The patients with osteosarcoma can obtain better life quality after limb salvage compared to amputation,while the two treatments are similar to each other in limb function.

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備注/Memo

備注/Memo:
通訊作者:龐清江 E-mail:[email protected]
更新日期/Last Update: 2017-12-29