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[1]龔江浩.股骨近端防旋髓內(nèi)釘聯(lián)合抗骨質(zhì)疏松藥物治療 不穩(wěn)定型老年股骨轉(zhuǎn)子間骨折的臨床觀察[J].中醫(yī)正骨,2015,27(04):29-32.
　GONG Jianghao.A combination therapy of proximal femoral nail antirotation and anti-osteoporotic drugs for the treatment of unstable femoral intertrochanteric fractures in the aged[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(04):29-32.
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股骨近端防旋髓內(nèi)釘聯(lián)合抗骨質(zhì)疏松藥物治療 不穩(wěn)定型老年股骨轉(zhuǎn)子間骨折的臨床觀察()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第27卷
期數(shù):
2015年04期
頁碼:
29-32
欄目:
臨床研究
出版日期:
2015-04-30

文章信息/Info

Title:
A combination therapy of proximal femoral nail antirotation and anti-osteoporotic drugs for the treatment of unstable femoral intertrochanteric fractures in the aged
作者:
龔江浩
溫州醫(yī)科大學(xué)附屬義烏醫(yī)院,浙江 義烏 322000
Author(s):
GONG Jianghao
Yiwu Hospital Affiliated to Wenzhou Medical University,Yiwu 322000,Zhejiang,China
關(guān)鍵詞:
髖骨折;  轉(zhuǎn)子間骨折;  抗骨質(zhì)疏松藥;  骨質(zhì)疏松;  老年人;  股骨近端防旋髓內(nèi)釘;  骨密度;  骨痂;  治療; 臨床研究性
Keywords:
hip fractures;  intertrochanteric fractures;  anti-osteoporotic;  osteoporosis;  aged;  proximal femoral nail antirotation;  bone density;  bony callus;  therapies; investigational
摘要:
目的:探討股骨近端防旋髓內(nèi)釘(proximal femoral nail antirotation,PFNA)聯(lián)合抗骨質(zhì)疏松藥物治療老年不穩(wěn)定型股骨轉(zhuǎn)子間骨折的臨床療效。方法:將納入研究的140例股骨轉(zhuǎn)子間骨折患者隨機(jī)分為聯(lián)合治療組和PFNA組。聯(lián)合治療組采用PFNA內(nèi)固定術(shù)聯(lián)合口服阿法骨化醇軟膠囊、強(qiáng)骨膠囊及維生素D治療,PFNA組單純采用PFNA內(nèi)固定治療。觀察住院時(shí)間、骨痂出現(xiàn)時(shí)間、骨折愈合時(shí)間及術(shù)后6個(gè)月時(shí)的Harris髖關(guān)節(jié)評(píng)分和骨密度。結(jié)果:2組患者住院時(shí)間及術(shù)后6個(gè)月Harris評(píng)分比較,組間差異均無統(tǒng)計(jì)學(xué)意義[(15.55±5.13)d,(16.04±5.44)d,t=0.805,P=0.611;(86.23±6.55)分,(85.14±6.06)分,t=1.006,P=0.239]; 與PFNA組相比,聯(lián)合治療組骨痂出現(xiàn)早,骨折愈合快,術(shù)后6個(gè)月時(shí)Ward三角、股骨頸及股骨大轉(zhuǎn)子的骨密度更高[(29.38±4.67)d,(37.55±5.32)d,t=6.126,P=0.009;(3.11±1.14)月,(3.56±1.27)月,t=5.007,P=0.013;(0.877±0.024)g·cm-2,(0.648±0.012)g·cm-2,t=9.552,P=0.001;(1.011±0.064)g·cm-2,(0.802±0.018)g·cm-2,t=11.227,P=0.000;(0.882±0.035)g·cm-2,(0.686±0.023)g·cm-2,t=8.217,P=0.002]。結(jié)論:在PFNA內(nèi)固定的基礎(chǔ)上聯(lián)合應(yīng)用抗骨質(zhì)疏松藥物,可提高老年不穩(wěn)定型股骨轉(zhuǎn)子間骨折患者的骨密度,加快骨折愈合。
Abstract:
Objective:To observe the clinical curative effects of proximal femoral nail antirotation(PFNA)combined with anti-osteoporotic drugs in the treatment of unstable femoral intertrochanteric fractures in the aged.Methods:One hundred and forty patients with femoral intertrochanteric fractures enrolled in the study were randomly divided into combination treatment group and PFNA group.The patients in combination treatment group were treated with PFNA internal fixation combined with oral application of alfacalcidol soft capsules,Qianggu(強(qiáng)骨)capsules and Vitamin D(Vit D); while the others in PFNA group were treated with the monotherapy of PFNA internal fixation.The hospital stay,bony callus and fracture healing time were observed.Harris hip scores and bone density were evaluate at six months after surgery.Results:There was no statistical difference in hospital stay and Harris scores at six months after surgery between the two groups(15.55+/-5.13 vs 16.04+/-5.44 days,t=0.805,P=0.611; 86.23+/-6.55 vs 85.14+/-6.06 points,t=1.006,P=0.239).Compared with PFNA group,combination treatment group has shorter bony callus appearing time,shorter fracture healing time and higher bone density of Ward's triangle,femoral neck and greater trochanter of femur at six months after surgery(29.38+/-4.67 vs 37.55+/-5.32 days,t=6.126,P=0.009; 3.11+/-1.14 vs 3.56+/-1.27 months,t=5.007,P=0.013; 0.877+/-0.024 vs 0.648+/-0.012 g/cm(2),t=9.552,P=0.001; 1.011+/-0.064 vs 0.802+/-0.018 g/cm(2),t=11.227,P=0.000; 0.882+/-0.035 vs 0.686+/-0.023 g/cm(2),t=8.217,P=0.002).Conclusion:Combination of anti-osteoporosis drugs with PFNA internal fixation can improve the bone density of aged patients with unstable femoral intertrochanteric fractures and accelerate fracture healing.

參考文獻(xiàn)/References:

[1] 崔樹森,趙意華.老年股骨粗隆間骨折內(nèi)固定術(shù)后抗骨質(zhì)疏松藥物治療的療效分析[J].中國(guó)骨與關(guān)節(jié)損傷雜志,2014,29(2):138-140.
[2] Yeung M,Bhandari M.Uneven global distribution of randomized trials in hip fracture surgery[J].Acta Orthop,2012,83(4):328-333.
[3] 國(guó)家中醫(yī)藥管理局.中醫(yī)病證診斷療效標(biāo)準(zhǔn)[S].南京:南京大學(xué)出版社,1994:170.
[4] 中國(guó)老年學(xué)學(xué)會(huì)骨質(zhì)疏松委員會(huì)骨質(zhì)疏松診斷標(biāo)準(zhǔn)學(xué)科組.中國(guó)人原發(fā)性骨質(zhì)疏松癥診斷標(biāo)準(zhǔn)(試行)[J].中國(guó)骨質(zhì)疏松雜志,1992,5(1):1-3.
[5] 樊仕才,金大地,蘇訓(xùn)同,等.老年股骨粗隆間骨折術(shù)后再發(fā)對(duì)側(cè)粗隆間骨折的原因分析及治療策略[J].中華關(guān)節(jié)外科雜志:電子版,2010,4(4):477-481.
[6] Cheng T,Zhang GY,Zhang XL.Minimally invasive versus conventional dynamic hip screw fixation in elderly patients with intertrochanteric fractures:a systematic review and Meta-Analysis[J].Surg Innov,2011,18(2):99-105.
[7] 蔣銘,徐鋒,孫斌峰,等.股骨近端防旋髓內(nèi)釘內(nèi)固定配合中藥內(nèi)服治療老年股骨轉(zhuǎn)子間骨折[J].中醫(yī)正骨,2014,26(7):17-19.
[8] 劉國(guó)輝,陳東,楊述華,等.強(qiáng)骨膠囊治療骨質(zhì)疏松性股骨轉(zhuǎn)子間骨折的臨床觀察[J].中西醫(yī)結(jié)合研究,2010,2(1):4-6.
[9] Setiobudi T,Ng YH,Lim CT,et al.Clinical outcome following treatment of stable and unstable intertrochanteric fractures with dynamic hip screw[J].Ann Acad Med Singapore,2011,40(11):482-487.
[10] 徐偉,王志巖,師佩蘭,等.動(dòng)力髖螺釘治療老年性股骨粗隆間骨折的療效分析[J].中華全科醫(yī)學(xué),2014,12(7):1044-1046.
[11] O'Malley NT,Deeb AP,Bingham KW,et al.Outcome of the dynamic helical hip screw system for intertrochanteric hip fractures in the elderly patients[J].Geriatr Orthop Surg Rehabil,2012,3(2):68-73.
[12] 廖紅波,田野.解剖型鎖定鋼板固定治療股骨粗隆部粉碎骨折[J].實(shí)用骨科雜志,2011,17(3):250-252.
[13] Zeng C,Wang YR,Wei J,et al.Treatment of trochanteric fractures with proximal femoral nail antirotation or dynamic hip screw systems:a meta-analysis[J].J Int Med Res,2012,40(3):839-851.
[14] 錢明權(quán),朱國(guó)興,陳剛.動(dòng)力髖螺釘聯(lián)合防旋阻擋釘與股骨近端髓內(nèi)釘治療不穩(wěn)定型股骨粗隆間骨折的對(duì)比研究[J].中國(guó)矯形外科雜志,2013,21(10):957-962.
[15] 屈波,伍紅樺,鄧少林,等.老年股骨粗隆間骨折的手術(shù)治療:應(yīng)用DHS與PFNA的療效比較[J].軍事醫(yī)學(xué),2014,38(1):67-69.
[16] Van Ness PH,Peduzzi PN,Quagliarello VJ.Efficacy and effectiveness as aspects of cluster randomized trials with nursing home residents:Methodological insights from a pneumonia prevention trial[J].Contemp Clin Trials,2012,33(6):1124-1131.
[17] 黃宏杰,范海泉,黃海訊,等.PFNA與DHS治療老年股骨粗隆間骨折臨床療效比較[J].四川醫(yī)學(xué),2012,33(8):1403-1405.
[18] 米寧,高仕長(zhǎng).PFNA與DHS治療高齡股骨轉(zhuǎn)子間骨折臨床療效對(duì)比研究[J].重慶醫(yī)學(xué),2013,42(28):3353-3354.
[19] 楊國(guó)志,李振武,尹銳峰,等.強(qiáng)骨膠囊聯(lián)合鮭魚降鈣素針劑輔助治療老年骨質(zhì)疏松性壓縮骨折臨床觀察[J].中國(guó)骨質(zhì)疏松雜志,2014,20(2):196-199.

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備注/Memo

備注/Memo:
2014-12-09收稿 2015-01-16修回
更新日期/Last Update: 2015-04-30