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[1]王西迅,李鈞,陳旭輝,等.木豆葉煎液外洗治療四肢創(chuàng)傷創(chuàng)面的臨床觀察[J].中醫(yī)正骨,2013,25(11):8-12.
　Wang Xixun*,Li JJun,Chen Xuhui,et al.Therapeutic effect of cajanus leaf decoction washing on the treatment of wound surfaces in the limbs[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(11):8-12.
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木豆葉煎液外洗治療四肢創(chuàng)傷創(chuàng)面的臨床觀察()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第25卷
期數(shù):
2013年11期
頁碼:
8-12
欄目:
臨床研究
出版日期:
2013-11-30

文章信息/Info

Title:
Therapeutic effect of cajanus leaf decoction washing on the treatment of wound surfaces in the limbs
作者:
王西迅1; 李鈞1; 陳旭輝2;  楊勇1; 周順3; 崔巖1; 陳波1; 金成1;  禹建春4;  胡繼超1;  舒正華1; 魏勇1; 何健1; 童哲1; 潘 躍1; 丁潮琪1
1.中國武裝警察部隊(duì)浙江省總隊(duì)醫(yī)院,浙江 嘉興 314000;
2.浙江新安國際醫(yī)院,浙江 嘉興 314000;
3.浙江省平湖市中醫(yī)院,浙江 平湖 314200;
4.浙江省臺(tái)州市博愛醫(yī)院,浙江 臺(tái)州 318050
Author(s):
Wang Xixun*; Li JJun; Chen Xuhui; Yang Yong; Zhou Shun; Cui Yan; Chen Bo; Jin Cheng; Yu Jianchun; Hu Jichao; Shu Zhenghua; Wei Yong; He Jian; Tong Zhe; Pan Yue; Ding Chaoqi.*
General Hospital in Zhejiang Province of Armed Police Forces,Jiaxing 314000,Zhejiang,China
關(guān)鍵詞:
軟組織損傷 傷口愈合 木豆 治療; 臨床研究性
Keywords:
Soft tissue injuries;  Wound healing;  Cajanus;  Therapies; investigational
摘要:
目的:觀察木豆葉煎液外洗治療四肢軟組織缺損的臨床療效。方法:將226例軟組織缺損患者隨機(jī)分為2組,每組113例。清創(chuàng)結(jié)束后,治療組用木豆葉煎液外洗處理創(chuàng)面,對照組用5%呋喃西林溶液處理創(chuàng)面。每日2次。觀察2組患者的創(chuàng)面愈合率、創(chuàng)面愈合時(shí)間、創(chuàng)面分泌物細(xì)菌培養(yǎng)結(jié)果及臨床療效。結(jié)果:①創(chuàng)面愈合率。治療后不同時(shí)間患者的創(chuàng)面愈合率的差異總體上有統(tǒng)計(jì)學(xué)意義,即存在時(shí)間效應(yīng)(F=111.562,P=0.000); 2組患者治療后不同時(shí)間創(chuàng)面愈合率的組間差異總體上有統(tǒng)計(jì)學(xué)意義,即存在分組效應(yīng)(F=1757.082,P=0.000),治療組各時(shí)間點(diǎn)創(chuàng)面愈合率均高于對照組[(54.43±24.77),(42.96±19.99),t=5.171,P=0.006;(83.74±13.79),(55.81±21.59),t=15.746,P=0.000;(94.07±9.28),(65.37±21.80),t=17.163,P=0.000;(97.49±6.16),(77.75±20.76),t=13.875,P=0.000]; 時(shí)間因素和分組因素存在交互效應(yīng)(F=188.500,P=0.003)。②創(chuàng)面愈合時(shí)間。治療組創(chuàng)面愈合時(shí)間比對照組短,差異有統(tǒng)計(jì)學(xué)意義[(33.47±7.22),(43.37±11.39),t=-11.692,P=0.008]。③創(chuàng)面分泌物細(xì)菌培養(yǎng)結(jié)果。治療前2組患者創(chuàng)面分泌物細(xì)菌培養(yǎng)陽性率比較,差異無統(tǒng)計(jì)學(xué)意義(χ2=0.398,P=0.528),治療開始后1周、2周、3周、4周治療組創(chuàng)面分泌物細(xì)菌培養(yǎng)陽性率均低于對照組,差異有統(tǒng)計(jì)學(xué)意義(χ2=33.275,P=0.000; χ2=20.884,P=0.000; χ2=11.760,P=0.001; χ2=7.706,P=0.006)。④臨床療效。治療組治愈88例、顯效23例、有效2例,對照組治愈12例、顯效45例、有效39例、無效17例。治療組療效優(yōu)于對照組(u=1 474.500,P=0.000)。結(jié)論:木豆葉煎液能提高創(chuàng)面愈合率,縮短創(chuàng)面愈合時(shí)間,抑制創(chuàng)面細(xì)菌繁殖,可有效促進(jìn)四肢軟組織創(chuàng)傷創(chuàng)面的愈合。
Abstract:
Objective:To observe the clinical effects of cajanus leaf decoction washing on the treatment of soft tissue defects in the limbs.Methods:Two hundred and twenty-six patients with soft tissue defects were randomly divided into treatment group and control group,113 cases in each group.After debridement,the patients in treatment group were treated with cajanus leaf decoction washing,while the others in control group were treated with 5% nitrofurazone solution washing,2 times a day.Then the wound healing rate,healing time,wound secretion germiculture result and clinical effects were observed between the 2 groups.Results:In general,there was statistical difference in wound healing rate among time points(F=111.562,P=0.000),in other words,there was time effect.There was statistical difference in wound healing rate between the 2 groups in general(F=1757.082,P=0.000),in other words,there was group effect.The wound healing rate of treatment group was higher than that of control group at each time points((54.43+/-24.77),(42.96+/-19.99),t=5.171,P=0.006;(83.74+/-13.79),(55.81+/-21.59),t=15.746,P=0.000;(94.07+/-9.28),(65.37+/-21.80),t=17.163,P=0.000;(97.49+/-6.16),(77.75+/-20.76),t=13.875,P=0.000).There was interaction between time factor and grouping factor(F=188.500,P=0.003).The wound healing time of treatment group was shorter than that of control group,and there was statistical difference between the 2 groups((33.47+/-7.22),(43.37+/-11.39),t=-11.692,P=0.008).There was no statistical difference in the germiculture positive rate of wound secretion between the 2 groups before treatment(χ2=0.398,P=0.528),the germiculture positive rate of wound secretion in treatment group was lower than that of control group 1 week,2 weeks,3 weeks and 4 weeks after treatment,and there were statistical differences between the 2 groups(χ2=33.275,P=0.000; χ2=20.884,P=0.000; χ2=11.760,P=0.001; χ2=7.706,P=0.006).Eighty-eight patients obtained an excellent clinical curative effects,23 good,and 2 fair in the treatment group; while 12 patients obtained an excellent clinical curative effects,45 good,39 fair,and 17 poor in the control group.The treatment group surpassed the control group in the total curative effect(u=1 474.500,P=0.000).Conclusion:The therapy of cajanus leaf decoction washing can improve wound healing rate,shorten the wound healing time,inhibit wound bacteria breeding,so it can promote the wound healing of soft tissue in the limbs effectively.

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備注/Memo

備注/Memo:
2013-05-18收稿 2013-10-09修回
基金項(xiàng)目:浙江省嘉興市科技計(jì)劃項(xiàng)目(2009AY2056)
更新日期/Last Update: 2013-11-30