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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:

第25卷

期數(shù):

2013年08期

頁碼:

10-12

欄目:

臨床研究

出版日期:

2013-08-30

文章信息/Info

Title:

Clinical analysis of comprehensive therapy on synovitis of hip secondary to ankylosing spondylitis

作者:

赫軍¹; 李麗華²; 諸葛天瑜¹; 孫捷¹; 湯志剛¹; 赫輝²

1.浙江省臺(tái)州市博愛醫(yī)院,浙江 臺(tái)州 318050;
2.河南風(fēng)濕病醫(yī)院,河南 鄭州 450045

Author(s):

Jun^*; Li Lihua; Zhuge Tianyu; Sun Jie; Tang Zhigang; He Hui.^*

Boai Hospital of Taizhou City,Taizhou 318050,Zhejiang,China

關(guān)鍵詞:

強(qiáng)直性脊柱炎 滑囊炎 髖關(guān)節(jié) 中醫(yī)藥治療 臭氧

Keywords:

Ankylosing spondylitis;  Synovitis; hip joint;  Traditional Chinese medicine therapy;  Ozone

摘要:

目的:觀察采用中醫(yī)藥辨證內(nèi)服,結(jié)合髖關(guān)節(jié)局部注射臭氧及患髖下肢牽引和關(guān)節(jié)功能鍛煉等綜合療法治療AS髖關(guān)節(jié)滑膜炎的臨床療效。方法:將60例經(jīng)臨床及影像學(xué)證實(shí)滑膜炎AS住院患者,隨機(jī)分治療組與對(duì)照組,每組30例,治療組給予中藥辨證內(nèi)服,髖關(guān)節(jié)局部注射臭氧,下肢牽引,關(guān)節(jié)功能鍛煉等綜合療法治療,對(duì)照組給予柳氮磺胺吡啶片,美樂昔康片治療,共治療6周。治療后觀察對(duì)比2組患者的Harris評(píng)分,臨床療效及不良反應(yīng)情況。結(jié)果:①Harris評(píng)分:治療前2組患者Harris評(píng)分比較,差異無統(tǒng)計(jì)學(xué)意義(t=0.936,P=0.312); 治療后2組患者Harris評(píng)分均改善,治療組高于對(duì)照組(t=5.216,P=0.001)。②臨床療效:治療后2組患者的癥狀體征均改善,治療組臨床療效優(yōu)于對(duì)照組(χ²=0.312,P=0.000)。③不良反應(yīng):治療期間2組患者均未出現(xiàn)過敏反應(yīng)。治療組4例患者出現(xiàn)便溏,大便每日2次,心率加快2例; 對(duì)照組3例患者出現(xiàn)惡心,2例患者輕度肝功能受損。經(jīng)對(duì)癥處理后,2組患者不良反應(yīng)均消失。2組患者不良反應(yīng)發(fā)生率比較,差異無統(tǒng)計(jì)學(xué)意義(χ²=0.100,P=0.725)。結(jié)論:中醫(yī)藥辨證內(nèi)服,結(jié)合髖關(guān)節(jié)局部注射臭氧及患髖下肢牽引和關(guān)節(jié)功能鍛煉等綜合療法能改善AS髖關(guān)節(jié)滑膜炎臨床癥狀體征及關(guān)節(jié)功能,且無嚴(yán)重不良反應(yīng),具有臨床應(yīng)用價(jià)值。

Abstract:

Objective:To observe the clinical efficacy of oral administration of traditional Chinese medicine(TCM)combined with local injection of ozone in hip joint,lower limb traction,functional exercise in the treatment of hip synovitis secondary to ankylosing spondylitis(AS).Method:60 hospitalized patients with synovitis secondary to AS confirmed clinically and radiographically were randomly divided into treatment group and control group with 30 cases in each group,the treatment group was given Chinese traditional medicine taken orally,local injection of ozone in hip joint,lower limb traction and joint functional exercise for six weeks.The control group was given Sulfasalazine tablets and Miller piroxicam tablets for six weeks.The harris hip scores,clinical efficacy and adverse reaction were compared between the two groups after treatment.Result:①Harris hip score:There was no significant difference in Harris hip score between the groups before treatment(t=0.936,P=0.312 ); the harris hip score of treatment group was higher than that of control group(t=5.216,P=0.001)after treatment.②The clinical efficacy:The symptoms and signs after treatment in both groups were improved,the effect in treatment group was superior to that in the control group(χ2=0.312,P=0.000).③Adverse reaction:No allergic reaction was observed during treatment in both groups.Loose stool with 2 times a day appeared in 4 cases of the treatment group,rapid heart rate appeared in 2 cases; 3 cases of the control group patients showed nausea,2 cases of patients with mild liver function damage.After proper treatment adverse reaction disappeared in the two groups.There was no significant difference in incidence of adverse reaction between the two groups(χ2=0.100,P=0.725).Conclusion:Oral administration of TCM combined with local injection of ozone in the hip,lower limb traction,joint function exercise could improve the clinical symptoms and function of joint of the AS hip synovitis,and with no serious adverse reaction,is of great value in clinical application.

備注/Memo

備注/Memo:

2013-02-22收稿 2013-07-04修回

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更新日期/Last Update: 2013-08-30