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[1]胡勁濤,許超,韓耀靜,等.抑郁與絕經(jīng)后女性骨密度的相關(guān)性研究[J].中醫(yī)正骨,2013,25(02):22-24.
　HU Jin-tao*,XU Chao,HAN Yao-jing,et al.Correlation between depression and bone mineral density in postmenopausal women[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(02):22-24.
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抑郁與絕經(jīng)后女性骨密度的相關(guān)性研究()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第25卷
期數(shù):
2013年02期
頁碼:
22-24
欄目:
臨床研究
出版日期:
2013-02-20

文章信息/Info

Title:
Correlation between depression and bone mineral density in postmenopausal women
作者:
胡勁濤1; 許超2; 韓耀靜2; 孫國麗2
1.浙江中醫(yī)藥大學(xué)第二臨床醫(yī)學(xué)院,浙江 杭州 310005;
2.浙江中醫(yī)藥大學(xué)附屬第二醫(yī)院,浙江 杭州 310005
Author(s):
HU Jin-tao*; XU Chao; HAN Yao-jing; SUN Guo-li.
*No.2 Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310005,Zhejiang,China
關(guān)鍵詞:
絕經(jīng)后 女性 骨密度 抑郁
Keywords:
Post-menopause; Female; Bone mineral density; Depression
摘要:
目的:探討抑郁情志與絕經(jīng)后女性腰椎骨密度的相關(guān)性。方法:收集70名受訪者,采用Medilink雙能X線骨密度儀測量骨密度及漢密爾頓抑郁調(diào)查量表評估抑郁值,將受訪者分為骨質(zhì)疏松組與非骨質(zhì)疏松組進(jìn)行比較分析,同時(shí)分別對兩組受訪者抑郁和骨密度進(jìn)行相關(guān)性分析。結(jié)果:骨質(zhì)疏松組與非骨質(zhì)疏松組抑郁值之間存在顯著差異(13.2±7.6 VS 5.2±7.1,F=-4.055,P=0.000),且骨質(zhì)疏松組L1、L2、L3、L4和總體腰椎骨密度值與抑郁呈負(fù)相關(guān),相關(guān)系數(shù)分別為-0.653(P=0.000)、-0.425(P=0.010)、-0.447(P=0.006)、-0.376(P=0.024)、-0.618(P=0.000),非骨質(zhì)疏松組它們兩者之間無相關(guān)性。結(jié)論:抑郁與骨密度之間存在關(guān)聯(lián)性,抑郁越嚴(yán)重骨密度值越低,抑郁是骨質(zhì)疏松癥加劇的因素之一。
Abstract:
Objective:To investigate the correlation between depressive emotion and lumbar bone mineral density of the postmenopausal women.Methods:To collect 70 respondents,using Medilink dual energy X-ray absorptiometry measurements in subjects for bone mineral density and the Hamilton depression inventory to assess depression value,the respondents were divided into osteoporosis group and non-osteoporosis group to compare.Meanwhile,correlation of depression value and bone mineral density of two groups were analysised respectively.Results:The osteoporosis group and non-osteoporosis group differences in depression value(13.2±7.6 VS 5.2±7.1,F=-4.055,P=0.000),L1,L2,L3,L4 and total lumbar bone density were negative correlative with depression scores,the correlation coefficients were -0.653(P=0.000),-0.425(P=0.010),-0.447(P=0.006),-0.376(P=0.024),-0.618(P=0.000),but there was no correlation between them in osteoporosis group.Conclusion:Depression and bone mineral density have certain relationship.The more depressed people have a lower bone mineral density.Depression is one of the factors can aggravate osteoporosis.

參考文獻(xiàn)/References:

[1] 許超,肖魯偉,童培建,等.骨質(zhì)疏松癥的中醫(yī)辯證分型客觀化研究[J].中醫(yī)正骨,2010,22(2):27-30.
[2] 許超,肖魯偉,吳承亮.絕經(jīng)后女性骨質(zhì)疏松癥辨證分型與抑郁焦慮的關(guān)系研究[J].中醫(yī)正骨,2011,23(12):3-5.
[3] Cizza G,Primma S,Csako G.Depression as a risk factor for osteoporosis[J]. Trends Endocrinol Metab, 2009, 20: 367-373.
[4] Williams LJ,Bjerkeset O,Langhammer A,et al.The association between depressive and anxiety symptoms and bone mineral density in the general population:The HUNT Study[J].Journal of Affective Disord,2011,131(1-3):164-171.
[5] Oh SM,Kim HC,Ahn SV,et al.Association between depression and bone mineral density in community-dwelling older men and women in Korea[J].Maturitas,2012,71(2):142-146.
[6] Whooley MA,Kip KE,Cauley JA,et al.Depressive symptoms and bone mineral density in older men[J].J Geriatry Psychiatry Neurol,2004,17:88-92.

備注/Memo

備注/Memo:
基金項(xiàng)目:浙江省自然科學(xué)基金項(xiàng)目(Y2111258)
通訊作者:許超 E-mail:[email protected]
更新日期/Last Update: 2013-02-20