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[1]阮朝陽,曾強華,朱群威.丹參注射液預防全髖關節(jié)置換術后靜脈血栓栓塞[J].中醫(yī)正骨,2013,25(01):30-32.
　RUAN Zhao-yang*,ZENG Qiang-hua,ZHU Qun-wei..Clinical study on the curative effect and safety of DANSHEN injection in the prevention of venous thromboembolism after total hip arthroplasty[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(01):30-32.
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丹參注射液預防全髖關節(jié)置換術后靜脈血栓栓塞()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第25卷
期數:
2013年01期
頁碼:
30-32
欄目:
關節(jié)置換
出版日期:
2013-01-20

文章信息/Info

Title:
Clinical study on the curative effect and safety of DANSHEN injection in the prevention of venous thromboembolism after total hip arthroplasty
作者:
阮朝陽; 曾強華; 朱群威
浙江省海寧市人民醫(yī)院,浙江 海寧 314400
Author(s):
RUAN Zhao-yang*; ZENG Qiang-hua; ZHU Qun-wei.
*The People's Hospital of Haining City,Haining 314400,Zhejiang,China
關鍵詞:
靜脈血栓形成 肺栓塞 丹參注射液 關節(jié)成形術; 置換; 髖 治療; 臨床研究性
Keywords:
Venous thrombosis;  Pulmonary embolism;  DANSHEN injection;  Arthroplasty; replacement; hip;  Therapies; investigational
摘要:
目的:觀察丹參注射液預防全髖關節(jié)置換術后靜脈血栓栓塞的臨床療效和安全性。方法:將納入研究的132例需要進行全髖關節(jié)置換的患者分為2組,A組67例,B組65例。所有患者術前1 d停用促凝血藥物。采用硬膜外麻醉; 術中處理股骨前,靜脈注射肝素鈉注射液15 U·kg-1,并徹底吸出股骨髓腔內容物; 處理股骨時,盡量縮短下肢保持在同一位置的時間; 術后立即開始使用周期性充氣加壓裝置14 d,患肢穿彈力襪,同時鼓勵患者盡早開始踝關節(jié)跖屈和背伸鍛煉。A組患者從術后第1天開始靜脈滴注丹參注射液(20 mL丹參注射液加入250 mL生理鹽水),每天1次,連用14 d; B組患者從術后第1天開始皮下注射低分子肝素鈣,每次0.4 mL,每天1次,連用14 d。觀察比較2組患者術后靜脈血栓栓塞的發(fā)生率,比較2組患者圍手術期的出血量和血紅蛋白下降值及術后血腫和胃腸道出血的發(fā)生率。結果:①臨床療效。A組1例患者發(fā)生非致命性肺血栓栓塞癥,6例患者發(fā)生深靜脈血栓形成; B組2例患者發(fā)生深靜脈血栓形成。2組患者肺血栓栓塞癥和深靜脈血栓形成發(fā)生率組間比較,差異均無統(tǒng)計學意義(P=1.000; χ2=1.103,P=0.294)。②安全性。A組患者的圍手術期出血量[(529.60±386.80)mL]和血紅蛋白下降值[(33.04±17.03)g·L-1]與B組[(548.75±403.46)mL,(35.01±21.04)g·L-1]比較,差異均無統(tǒng)計學意義(t=0.783,P=0.474; t=1.292,P=0.193)。A組1例患者發(fā)生胃腸道出血; B組1例患者出現(xiàn)血腫,1例患者發(fā)生胃腸道出血。2組患者血腫及胃腸道出血發(fā)生率組間比較,差異均無統(tǒng)計學意義(P=0.492; P=1.000)。結論:丹參注射液預防全髖關節(jié)置換術后靜脈血栓栓塞的療效和安全性與低分子肝素相當。
Abstract:
Objective:To observe the clinical curative effect and safety of DANSHEN injection in the prevention of venous thromboembolism(VTE)after total hip arthroplasty(THA).Methods:One hundred and thirty-two patients considering THA were divided into 2 groups,67 cases in group A,while the others in group B.All the patients stopped using blood coagulant 1 day before the operation and epidural anesthesia was used during the operation.Heparin sodium injection(15 U/kg iv)was used before management of femur and the contents of femoral bone marrow cavity were sucked out completely.The time of keeping lower limbs in the same position was shortened as much as possible.The intermittent pneumatic compression device was immediately used after operation for 14 days,and the stretch socks were used for the affected limbs,and the patients were also encouraged to do ankle plantar flexion and dorsiflexion exercise as early as possible.Patients in group A were administrated with intravenous drip of DANSHEN injection(20 ml DANSHEN injection combined with 250 ml normal saline)from the 1st day after operation,once per day for 14 days,while the patients in group B were administrated with hypodermic injection of 0.4 ml low molecular weight heparin calcium injection from the 1st day after operation,once per day for 14 days.Such parameters were observed and compared between the 2 groups after the operation as the incidence rate of VTE,hematoma and gastrointestinal bleeding,the blood loss and hemoglobin loss during perioperative period.Results:One patient with non-lethal pulmonary thromboembolism(PTE)and 6 patient s with deep venous thrombosis(DVT)were found in group A,while 2 patients with DVT were found in group B.There were no statistical differences in the incidence rate of PTE and DVT between the 2 groups(P=1.000; χ2=1.103,P=0.294).There were no statistical differences in blood loss and hemoglobin loss between group A((529.60±386.80)ml,(33.04±17.03)g/l)and group B((548.75±403.46)ml,(35.01±21.04)g/l)respectively(t=0.783,P=0.474; t=1.292,P=0.193).One patient with gastrointestinal bleeding was found in group A,while 1 patient with hematoma and 1 patient with gastrointestinal bleeding were found in group B.There were no statistical differences in the incidence rate of hematoma and gastrointestinal bleeding between the 2 groups(P=0.492; P=1.000).Conclusion:DANSHEN injection is similar to low molecular weight heparin calcium in the curative effect and safety for prevention of venous thromboembolism after total hip arthroplasty.

參考文獻/References:

[1] Heit JA,O'Fallon WM,Petterson TM,et al.Relative impact of risk factors for deep vein thrombosis and pulmonary embolism:a population-based study[J].Arch Intern Med,2002,162(11):1245-1248.
[2] Anderson FA Jr,Spencer FA.Risk factors for venous thromboembolism[J].Circulation,2003,107(23 Suppl 1):9-16.
[3] 林勝文,汪煌.彩色多普勒超聲檢查在下肢深靜脈血栓形成診斷中的應用[J].中醫(yī)正骨,2011,23(6):32-33.
[4] 邱貴興,戴尅戎,楊慶銘,等.預防骨科大手術后深靜脈血栓形成的專家建議[J].中華骨科雜志,2005,25(10):636-640.
[5] Dickson BC.Venous Thrombosis:On the History of Virchow's Triad[J].University of Toronto Medical Journal,2004,81(3):166-171.
[6] 邱貴興,楊慶銘,余楠生,等.低分子肝素預防髖、膝關節(jié)手術后下肢深靜脈血栓形成的多中心研究[J].中華骨科雜志,2006,26(12):819-822.
[7] Lotke PA.The role of aspirin for thromboembolic disease in total joint arthroplasty[J].Am J Knee Surg,1999,12(1):61-63.
[8] 章建華,童培建,袁臨益,等.丹參注射液防治下肢深靜脈血栓形成的實驗研究[J].中醫(yī)正骨,2005,17(9):3-4.
[9] Gomes MP,Deitcher SR.Risk of venous thromboembolic disease associated with hormonal contraceptives and hormone replacement therapy:a clinical review[J].Arch Intern Med,2004,164(18):1965-1976.
[10] Rosendaal FR,Helmerhorst FM,Vandenbroucke JP.Female hormones and thrombosis[J].Arterioscler Thromb Vasc Biol,2002,22(2):201-210.
[11] Sharrock NE,Ranawat CS,Urquhart B,et al.Factors influencing deep vein thrombosis following total hip arthroplasty under epidural anesthesia[J].Anesth Analg,1993,76(4):765-771.
[12] Sharrock NE,Salvati EA.Hypotensive epidural anesthesia for total hip arthroplasty:a review[J].Acta Orthop Scand,1996,67(1):91-107.

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更新日期/Last Update: 2013-01-20