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[1]陳志偉,石關(guān)桐,錢(qián)曉忠.膝骨關(guān)節(jié)炎與軟骨寡聚基質(zhì)蛋白的相關(guān)性研究進(jìn)展[J].中醫(yī)正骨,2012,24(12):33-35.
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膝骨關(guān)節(jié)炎與軟骨寡聚基質(zhì)蛋白的相關(guān)性研究進(jìn)展()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期數(shù):
2012年12期
頁(yè)碼:
33-35
欄目:
綜述
出版日期:
2012-12-20

文章信息/Info

作者:
陳志偉石關(guān)桐錢(qián)曉忠
上海中醫(yī)藥大學(xué)附屬曙光醫(yī)院寶山分院,上海 201900
關(guān)鍵詞:
骨關(guān)節(jié)炎膝 軟骨寡聚基質(zhì)蛋白 綜述
摘要:
膝骨關(guān)節(jié)炎是一種慢性、進(jìn)行性骨關(guān)節(jié)病,以關(guān)節(jié)軟骨進(jìn)行性退變與破壞、關(guān)節(jié)軟骨再修復(fù)、軟骨下骨重塑與硬化、骨贅形成及滑膜和關(guān)節(jié)腔的一系列生化及形態(tài)學(xué)改變?yōu)橹饕卣?其發(fā)病機(jī)制目前仍不清楚。軟骨寡聚基質(zhì)蛋白作為潛在的生物學(xué)標(biāo)記物應(yīng)用于膝骨關(guān)節(jié)炎的臨床診斷具有廣泛的應(yīng)用前景,但目前其特異性和敏感性還缺少相應(yīng)的循證醫(yī)學(xué)證據(jù)。本文對(duì)近年來(lái)膝骨關(guān)節(jié)炎、軟骨寡聚基質(zhì)蛋白及二者的相關(guān)性的研究進(jìn)展進(jìn)行了綜述。

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備注/Memo

備注/Memo:
通訊作者:石關(guān)桐 E-mail:[email protected]
更新日期/Last Update: 2012-12-20