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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:

第24卷

期數(shù):

2012年11期

頁碼:

3-6

欄目:

基礎(chǔ)研究

出版日期:

2012-11-20

文章信息/Info

Title:

To discuss the effects of point-through-point acupuncture with elongated needle to SCEP for spinal cord injury by animal experiment

作者:

全仁夫¹; 陳榮良¹; 許世超¹; 楊宗保²

1.浙江省杭州市蕭山區(qū)中醫(yī)院,浙江 杭州 311200;
2.江西中醫(yī)學(xué)院,江西 南昌 330004

Author(s):

QUAN Ren-fu^*; CHEN Rong-liang; XU Shi-chao; YANG Zong-bao.

^* TCM Hospital of Xiaoshan District of Hangzhou City,Hangzhou 311200,Zhejiang,China

關(guān)鍵詞:

脊髓損傷 芒針 秩邊 水道 脊髓誘發(fā)電位; 神經(jīng)傳導(dǎo)通路

Keywords:

Spinal cord Injury;  Elongated needle;  Zhibian acupoint;  Shuidao acupoint;  SCEP; nerve pathway

摘要:

目的:探討芒針透刺對脊髓損傷后脊髓誘發(fā)電位影響及其機(jī)理。方法:采用日本大耳兔以改良式ALLEN'S脊髓損傷法造模,將其分為模型組、芒針透刺組、假手術(shù)組,每組又分5小組:術(shù)后即刻組、術(shù)后3 d組、術(shù)后7 d組、術(shù)后14 d組、術(shù)后28 d組,以Tarlov評分、脊髓誘發(fā)電位之P2潛伏時和波幅為觀察指標(biāo),觀察芒針透刺秩邊-水道穴對下肢肌力感覺和脊髓誘發(fā)電位的影響。結(jié)果:兔脊髓損傷后均出現(xiàn)下肢癱瘓,經(jīng)治療5 d后芒針組較模型組tarlov評分明顯改善(P<0.01); 經(jīng)芒針治療4周后P2波幅較術(shù)后初期明顯增寬、增大,而4周后P2潛伏期較術(shù)后初期明顯縮短,基本恢復(fù)至術(shù)前水平,兩者與模型組比較均有統(tǒng)計學(xué)意義(P<0.05)。結(jié)論:芒針透刺能改善下肢癱瘓,促進(jìn)下肢肌力恢復(fù),加快脊髓誘發(fā)電位波幅和延遲時間的恢復(fù),其機(jī)理可能與修復(fù)脊髓神經(jīng)細(xì)胞及其神經(jīng)信號傳導(dǎo)通路,阻斷了神經(jīng)細(xì)胞及其神經(jīng)傳導(dǎo)通路的進(jìn)一步損傷等有關(guān)。

Abstract:

Objective:To discuss the effects of point-through-point acupuncture with elongated needle to SCEP for spinal cord injury(SPI)by animal experiment.Methods:Japanese rabbits taken as SPI model by modified ALLEN'S method were divided into 3 groups—blank group,model group,elongated needle acupuncture group.Every group was further divided into 5 groups:shortly after surgery,3 days after surgery,7 days after surgery,14 days after surgery,28 days after surgery.The indicators including the Tarlov score,incubate time of P2 and its volume in SCEP were observed.The indexes could indicate the relationship of acupuncture(acupoints:Zhibian-Shuidao)and myodynamia,SCEP as well.Results:All Japanese rabbits had lower limbs paralysis after spinal cord injury,after 5 days point-through-point acupuncture the Tarlov scores in elongated needle acupuncture group were improved compared with that in model group(P<0.01); their P2 waves after 4 weeks of treatment were wider and more magnified than that right after the surgery,the P2 incubation period reduced to the level before surgery,the differences were significant compared to model group(P<0.05).Conclusion:The point-through-point acupuncture with elongated needle is effective for the lower limb paralysis,it could accelerate the recovery of the myodynamia and increase the amplitude and incubate time of SCEP.The mechanism is properly related with helping the reparation of neurons in spinal cord and the signal transduction pathways,blocking-up of their further damage.

備注/Memo

備注/Memo:

基金項(xiàng)目:浙江省中醫(yī)藥科研計劃項(xiàng)目(2008CB067)

常用功能

更新日期/Last Update: 2012-11-20