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[1]黃建華,黃建武,阮利云,等.活動(dòng)期強(qiáng)直性脊柱炎血小板參數(shù)的表達(dá)及臨床價(jià)值[J].中醫(yī)正骨,2012,24(05):13-14.
　HUANG Jian-hua*,HUANG Jian-wu,RUAN Li-yun,et al.Expression and clinical value of platelet in activity ankylosing spondylitis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2012,24(05):13-14.
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活動(dòng)期強(qiáng)直性脊柱炎血小板參數(shù)的表達(dá)及臨床價(jià)值()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期數(shù):
2012年05期
頁碼:
13-14
欄目:
臨床研究
出版日期:
2012-05-20

文章信息/Info

Title:
Expression and clinical value of platelet in activity ankylosing spondylitis
作者:
黃建華; 黃建武; 阮利云; 李慧輝; 李強(qiáng)
溫州醫(yī)學(xué)院附屬第三醫(yī)院,浙江 瑞安 325200
Author(s):
HUANG Jian-hua*; HUANG Jian-wu; RUAN Li-yun; LI Hui-hui; Li Qiang.
*The third subsidiary Hospital of Zhejiang Wenzhou Medical College,Ruian 325200,Zhejiang,China
關(guān)鍵詞:
血小板 強(qiáng)直性脊柱炎 C反應(yīng)蛋白 臨床價(jià)值
Keywords:
Blood platrlets;  ankylosing spondylitis;  CRP;  Clinical value
摘要:
目的:研究血小板參數(shù)在活動(dòng)期強(qiáng)直性脊柱炎發(fā)病中的作用,探討其可能的機(jī)制及臨床價(jià)值。方法:采用全血細(xì)胞分析儀及免疫學(xué)檢測(cè)方法,檢測(cè)53名活動(dòng)期強(qiáng)直性脊柱炎患者和39名健康對(duì)照者靜脈血中血小板參數(shù)及C反應(yīng)蛋白,進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:活動(dòng)期強(qiáng)直性脊柱炎患者中靜脈血中血小板計(jì)數(shù)與C反應(yīng)蛋白水平均顯著高于健康對(duì)照組,血小板平均體積明顯低于健康對(duì)照組(P<0.05),且血小板計(jì)數(shù)與C反應(yīng)蛋白水平存在正相關(guān)(r=0.421,P<0.05),血小板平均體積與C反應(yīng)蛋白存在負(fù)相關(guān)(r=-0.325,P<0.05)。結(jié)論:血小板參數(shù)變化與活動(dòng)期強(qiáng)直性脊柱炎病情活動(dòng)有關(guān),可以作為監(jiān)控病情的反應(yīng)指標(biāo),與C反應(yīng)蛋白有同等的重要作用。
Abstract:
Objective:To explore the role of Platelet parameters(PLT、MPV)in activity ankylosing spondylitis,Discusses the mechanism and clinical value.Methods:by the whole blood cells analyser and immunology detection methods,detected the Venous blood platelets parameter(PLT、MPV)and CRP of 53 cases activity ankylosing spondylitis and 39 cases Health group,And do statistical analysis.Results:the CRP and PLT of activity ankylosing spondylitis are Significantly higher than health group,MPV significantly smaller than healthy group(P =0.000,P<0.05),there is positively correlated between PLT and CRP(r=0.421,P<0.05),MPV and CRP(r=-0.325,P<0.05),negative correlation exists.Conclusion:Platelet parameters(PLT,MPV)have relations with the activity ankylosing spondylitis disease,Can be used as a reaction index condition monitoring.And as the same important role of CRP.

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備注/Memo

備注/Memo:
基金項(xiàng)目:溫州衛(wèi)生局科研項(xiàng)目(2008002)
更新日期/Last Update: 2012-05-20