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[1]王戰(zhàn)朝,杜志謙,閆永昌,等.通經(jīng)活利湯治療膝關(guān)節(jié)滑膜炎的臨床研究[J].中醫(yī)正骨,2012,24(04):26-29.
　WANG Zhan-chao*,DU Zhi-qian,YAN Yong-chang,et al.Clinical study on the curative effect and safety of TONGJING HUOLI decoction in knee synovitis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2012,24(04):26-29.
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通經(jīng)活利湯治療膝關(guān)節(jié)滑膜炎的臨床研究()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期數(shù):
2012年04期
頁碼:
26-29
欄目:
臨床研究
出版日期:
2012-04-30

文章信息/Info

Title:
Clinical study on the curative effect and safety of TONGJING HUOLI decoction in knee synovitis
作者:
王戰(zhàn)朝1; 杜志謙1; 閆永昌2; 張曉強1; 尚延春1; 孟慶陽1
1.河南省洛陽正骨醫(yī)院,河南 洛陽 471002;
2.鄭州大學醫(yī)學院,河南 鄭州 450001
Author(s):
WANG Zhan-chao*; DU Zhi-qian; YAN Yong-chang; ZHANG Xiao-qiang; SHANG Yan-chun; MENG Qing-yang.*
Luoyang Orthopedic-Traumatological Hospital,Luoyang 471002,Henan,China
關(guān)鍵詞:
滑膜炎 膝關(guān)節(jié) 通經(jīng)活利湯 消炎藥; 非甾類 治療; 臨床研究性
Keywords:
Synovitis;  Knee joint;  TONGJING HUOLI DECOCTION;  Anti-inflammatory agents; non-steroidal;  Therapies; investigational
摘要:
目的:觀察通經(jīng)活利湯治療膝關(guān)節(jié)滑膜炎的臨床療效和安全性。方法:采用隨機數(shù)字表將符合要求的220例膝關(guān)節(jié)滑膜炎患者隨機分為2組,實驗組120例,對照組100例。實驗組患者采用通經(jīng)活利湯治療,對照組患者口服萘丁美酮膠囊,治療28 d后按照自擬的癥狀體征分級量化評分表對2組患者進行療效評定,同時觀察記錄2組患者治療期間發(fā)生胃腸道反應的情況。結(jié)果:①臨床療效。實驗組臨床療效優(yōu)于對照組(Z=-8.992,P=0.000)。②安全性。在治療期間實驗組1例出現(xiàn)胃腸道反應,對照組16例出現(xiàn)胃腸道反應,實驗組不良反應發(fā)生率低于對照組(χ2=17.597,P=0.000)。結(jié)論:通經(jīng)活利湯能明顯減輕膝關(guān)節(jié)滑膜炎患者膝的臨床癥狀,改善膝關(guān)節(jié)功能,其療效優(yōu)于萘丁美酮膠囊,而且不良反應也較非甾體類抗炎藥少。
Abstract:
Objective:To observe the curative effect and safety of TONGJING HUOLI decoction in knee synovitis.Methods:Two hundred and twenty patients with knee synovitis were randomly divided into 2 groups,120 cases in the experimental group,while the others in the control group.Patients in the experimental group were administrated with TONGJING HUOLI decoction,while the others in the control group were administrated with Nabumetone capsules.After 28 days treatment,the curative effects were evaluated according to the self-designed scoring scale of signs and symptoms.Meantime,the gastrointestinal reactions of patients occurred during the treatment period were observed and recorded.Results:The clinical curative effect of experimental group was better than that of control group(Z=-8.992,P=0.000).During the treatment period,1 case with gastrointestinal reaction was found in experimental group,while 16 cases with gastrointestinal reactions were found in control group.Incidence of adverse reactions of experimental group was lower than that of control group(χ2=17.597,P=0.000).Conclusion:TONGJING HUOLI decoction can significantly relieve knee clinical symptoms for the patients with knee synovitis and enhance knee function.Furthermore,its curative effect is better than that of Nabumetone capsules,and its adverse reactions are less than that of non-steroidal anti-inflammatory drugs.

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備注/Memo

備注/Memo:
2011-11-24收稿 2012-01-31修回
基金項目:河南省重點科技攻關(guān)項目(0623033300)
更新日期/Last Update: 2012-04-30