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[1]袁尚鋒.當(dāng)歸拈痛湯口服配合五藤散外敷治療濕熱痹阻型類風(fēng)濕關(guān)節(jié)炎45例臨床觀察[J].中醫(yī)正骨,2011,23(11):20-23.
　YUAN Shang-feng*.*.Clinical observation of Oral Danggui Niantong Decoction and Wuteng powder for 45 patients with rheumatoid arthritis of Moist Heat Arthralgia Spasm Syndrome[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2011,23(11):20-23.
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當(dāng)歸拈痛湯口服配合五藤散外敷治療濕熱痹阻型類風(fēng)濕 關(guān)節(jié)炎45例臨床觀察()
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《中醫(yī)正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第23卷
期數(shù):
2011年11期
頁碼:
20-23
欄目:
臨床研究
出版日期:
2011-11-30

文章信息/Info

Title:
Clinical observation of Oral Danggui Niantong Decoction and Wuteng powder for 45 patients with rheumatoid arthritis of Moist Heat Arthralgia Spasm Syndrome
作者:
袁尚鋒
湖南省株洲市中醫(yī)傷科醫(yī)院,湖南 株洲 412000
Author(s):
YUAN Shang-feng*.*
Department of Joint Surgery,Zhuzhou Chinese Traumatology Hospital,Zhuzhou 412000,Hunan,China
關(guān)鍵詞:
類風(fēng)濕關(guān)節(jié)炎 當(dāng)歸拈痛湯 五藤散 臨床研究
Keywords:
Arthritis;  Rheumatoid;  Danggui Niantong Decoction;  Wuteng Powder;  Clinical Observation
摘要:
目的:觀察當(dāng)歸拈痛湯口服配合五藤散外敷治療類風(fēng)濕關(guān)節(jié)炎的臨床療效及對相關(guān)免疫炎癥指標(biāo)的影響。方法:將90例類風(fēng)濕關(guān)節(jié)炎患者隨機(jī)分為兩組,治療組予當(dāng)歸拈痛湯口服配合五藤散外敷; 對照組用小劑量甲氨蝶呤治療,治療3個月后觀察相關(guān)免疫炎癥指標(biāo)變化并進(jìn)行療效評價。結(jié)果:治療組總有效率為91.11%,對照組總有效率為73.33%。治療組在改善晨僵時間、關(guān)節(jié)疼痛度、關(guān)節(jié)活動度、關(guān)節(jié)腫脹度、握力方面明顯優(yōu)于對照組(P<0.05或P<0.01)。治療組CRP 、ESR、RF、TNF-α、IL-6改善優(yōu)于對照組(P<0.05或P<0.01)。結(jié)論:當(dāng)歸拈痛湯口服配合五藤散外敷能有效抑制致免疫炎癥細(xì)胞因子產(chǎn)生和釋放,改善類風(fēng)濕關(guān)節(jié)炎癥狀體征,且無明顯副作用,是治療類風(fēng)濕關(guān)節(jié)炎的有效方劑。
Abstract:
Objective:To observe the curative effect of Oral Danggui Niantong Decoction and Wuteng powder for rheumatoid arthritis and the effect on relative immunological and inflammatory markers.Methods:Totally 90 patients with rheumatoid arthritis were randomly and equally divided into two groups.Oral Danggui Niantong Decoction and Wuteng powder was used in treatment group,while small dose methotrexate in control group.The relative immunological and inflammatory markers were observed and the curative effect of both groups was evaluated after three-month's treatment.Results:The total effective rate of treatment group was 91.11% and it was superior to 73.33% of control group.Improvements of morning stiffness duration,joint pain and swell,range of motion and grip strength in treatment group were superior to that in control group(P<0.05 or P<0.01).After Oral Danggui Niantong Decoction and Wuteng powder treatment,improvements of c-reactive protein(CRP),erythrocyte sedimentation rate(ESR),rheumatoid factor(RF),and tumor necrosis factor alpha(TNF-α),interleukin 6(IL-6)were superior to that in control group(P<0.05 or P<0.01).Conclusion:Oral Danggui Niantong Decoction and Wuteng powder can remarkably inhibit the production and release of relative immunological and inflammatory markers and improve the symptoms and signs of rheumatoid arthritis with no conspicuous side effects.It is a useful formula for treating rheumatoid arthritis.

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更新日期/Last Update: 1900-01-01